Plasma lipidome is dysregulated in Alzheimer’s disease and is associated with disease risk genes
出版年份 2021 全文链接
标题
Plasma lipidome is dysregulated in Alzheimer’s disease and is associated with disease risk genes
作者
关键词
-
出版物
Translational Psychiatry
Volume 11, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2021-06-07
DOI
10.1038/s41398-021-01362-2
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Converging and Differential Brain Phospholipid Dysregulation in the Pathogenesis of Repetitive Mild Traumatic Brain Injury and Alzheimer’s Disease
- (2019) Joseph O. Ojo et al. Frontiers in Neuroscience
- Plasma lipidome variation during the second half of the human lifespan is associated with age and sex but minimally with BMI
- (2019) Matthew Wai Kin Wong et al. PLoS One
- ApoE and clusterin CSF levels influence associations between APOE genotype and changes in CSF tau, but not CSF Aß42, levels in non-demented elderly
- (2019) Rosalinde E.R. Slot et al. NEUROBIOLOGY OF AGING
- Role of cholesterol and sphingolipids in brain development and neurological diseases
- (2019) Ghulam Hussain et al. Lipids in Health and Disease
- Astrocyte alterations in neurodegenerative pathologies and their modeling in human induced pluripotent stem cell platforms
- (2019) Minna Oksanen et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Association between increased levels of amyloid-β oligomers in plasma and episodic memory loss in Alzheimer’s disease
- (2019) Xue Meng et al. Alzheimers Research & Therapy
- Brain and blood metabolite signatures of pathology and progression in Alzheimer disease: A targeted metabolomics study
- (2018) Vijay R. Varma et al. PLOS MEDICINE
- Associations of the Top 20 Alzheimer Disease Risk Variants With Brain Amyloidosis
- (2018) Liana G. Apostolova et al. JAMA Neurology
- Cholesterol is Inefficiently Converted to Cholesteryl Esters in the Blood of Cardiovascular Disease Patients
- (2018) Mathias J. Gerl et al. Scientific Reports
- Altered bile acid profile associates with cognitive impairment in Alzheimer's disease—An emerging role for gut microbiome
- (2018) Siamak MahmoudianDehkordi et al. Alzheimers & Dementia
- Inverse Phosphatidylcholine/Phosphatidylinositol Levels as Peripheral Biomarkers and Phosphatidylcholine/Lysophosphatidylethanolamine-Phosphatidylserine as Hippocampal Indicator of Postischemic Cognitive Impairment in Rats
- (2018) Angelica Maria Sabogal-Guáqueta et al. Frontiers in Neuroscience
- Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
- (2017) Rebecca Sims et al. NATURE GENETICS
- Oligomeric forms of amyloid-β protein in plasma as a potential blood-based biomarker for Alzheimer’s disease
- (2017) Min Jeong Wang et al. Alzheimers Research & Therapy
- Studies on Colony Stimulating Factor Receptor-1 and Ligands Colony Stimulating Factor-1 and Interleukin-34 in Alzheimer's Disease Brains and Human Microglia
- (2017) Douglas G. Walker et al. Frontiers in Aging Neuroscience
- Sphingolipids: membrane microdomains in brain development, function and neurological diseases
- (2017) Anne S. B. Olsen et al. Open Biology
- Genome-wide, high-content siRNA screening identifies the Alzheimer’s genetic risk factor FERMT2 as a major modulator of APP metabolism
- (2016) Julien Chapuis et al. ACTA NEUROPATHOLOGICA
- Blood metabolite markers of preclinical Alzheimer's disease in two longitudinally followed cohorts of older individuals
- (2016) Ramon Casanova et al. Alzheimers & Dementia
- Graded perturbations of metabolism in multiple regions of human brain in Alzheimer's disease: Snapshot of a pervasive metabolic disorder
- (2016) Jingshu Xu et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Functional diversity of astrocytes in neural circuit regulation
- (2016) Lucile Ben Haim et al. NATURE REVIEWS NEUROSCIENCE
- Common variants in ABCA7 and MS4A6A are associated with cortical and hippocampal atrophy
- (2016) Leslie M. Ramirez et al. NEUROBIOLOGY OF AGING
- Genome-wide significant results identified for plasma apolipoprotein H levels in middle-aged and older adults
- (2016) Karen A. Mather et al. Scientific Reports
- Kindlin 3 (FERMT3) is associated with unstable atherosclerotic plaques, anti-inflammatory type II macrophages and upregulation of beta-2 integrins in all major arterial beds
- (2015) Niku Oksala et al. ATHEROSCLEROSIS
- The genetic landscape of Alzheimer disease: clinical implications and perspectives
- (2015) Caroline Van Cauwenberghe et al. GENETICS IN MEDICINE
- Immune attack: the role of inflammation in Alzheimer disease
- (2015) Frank L. Heppner et al. NATURE REVIEWS NEUROSCIENCE
- Investigating the Genetics of Hippocampal Volume in Older Adults without Dementia
- (2015) Karen A. Mather et al. PLoS One
- Cholesterol metabolism and homeostasis in the brain
- (2015) Juan Zhang et al. Protein & Cell
- Plasma lipidomics analysis finds long chain cholesteryl esters to be associated with Alzheimer’s disease
- (2015) P Proitsi et al. Translational Psychiatry
- Regularization Paths for Generalized Linear Models via Coordinate Descent
- (2015) Jerome Friedman et al. Journal of Statistical Software
- Lipidomics: Analysis of the Lipid Composition of Cells and Subcellular Organelles by Electrospray Ionization Mass Spectrometry
- (2014) Britta Brügger Annual Review of Biochemistry
- Is Alzheimer's disease a systemic disease?
- (2014) Jill K. Morris et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- PRSice: Polygenic Risk Score software
- (2014) Jack Euesden et al. BIOINFORMATICS
- Plasma phospholipids identify antecedent memory impairment in older adults
- (2014) Mark Mapstone et al. NATURE MEDICINE
- Functional screening in Drosophila identifies Alzheimer's disease susceptibility genes and implicates Tau-mediated mechanisms
- (2013) J. M. Shulman et al. HUMAN MOLECULAR GENETICS
- SORL1genetic variants modulate risk of amnestic mild cognitive impairment in northern Han Chinese
- (2013) Xin Gao et al. INTERNATIONAL JOURNAL OF NEUROSCIENCE
- Lipidomic analysis of brain tissues and plasma in a mouse model expressing mutated human amyloid precursor protein/tau for Alzheimer’s disease
- (2013) Yoko Tajima et al. Lipids in Health and Disease
- Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
- (2013) Jean-Charles Lambert et al. NATURE GENETICS
- Evidence of altered phosphatidylcholine metabolism in Alzheimer's disease
- (2013) Luke Whiley et al. NEUROBIOLOGY OF AGING
- Amyloid Precursor Protein Is an Autonomous Growth Cone Adhesion Molecule Engaged in Contact Guidance
- (2013) Lucas J. Sosa et al. PLoS One
- MicroRNA-34a Enhances T Cell Activation by Targeting Diacylglycerol Kinase ζ
- (2013) Jinwook Shin et al. PLoS One
- Mass and relative elution time profiling: two-dimensional analysis of sphingolipids in Alzheimer's disease brains
- (2011) Leila Hejazi et al. BIOCHEMICAL JOURNAL
- pROC: an open-source package for R and S+ to analyze and compare ROC curves
- (2011) Xavier Robin et al. BMC BIOINFORMATICS
- Reducing Plasma Membrane Sphingomyelin Increases Insulin Sensitivity
- (2011) Z. Li et al. MOLECULAR AND CELLULAR BIOLOGY
- Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
- (2011) Paul Hollingworth et al. NATURE GENETICS
- Epidemiology of Alzheimer disease
- (2011) Christiane Reitz et al. Nature Reviews Neurology
- Metabolomics in Early Alzheimer's Disease: Identification of Altered Plasma Sphingolipidome Using Shotgun Lipidomics
- (2011) Xianlin Han et al. PLoS One
- Plasma ceramides are altered in mild cognitive impairment and predict cognitive decline and hippocampal volume loss
- (2010) Michelle M. Mielke et al. Alzheimers & Dementia
- The Sydney Memory and Ageing Study (MAS): methodology and baseline medical and neuropsychiatric characteristics of an elderly epidemiological non-demented cohort of Australians aged 70–90 years
- (2010) Perminder S. Sachdev et al. INTERNATIONAL PSYCHOGERIATRICS
- SYMPOSIUM REVIEW: Lipid microdomains and the regulation of ion channel function
- (2010) Caroline Dart JOURNAL OF PHYSIOLOGY-LONDON
- Alterations of the Sphingolipid Pathway in Alzheimer’s Disease: New Biomarkers and Treatment Targets?
- (2010) Michelle M. Mielke et al. NEUROMOLECULAR MEDICINE
- Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
- (2009) Jean-Charles Lambert et al. NATURE GENETICS
- A Genome-Wide Association Study of Hypertension and Blood Pressure in African Americans
- (2009) Adebowale Adeyemo et al. PLoS Genetics
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started