β-Thalassemia

Non-invasive prenatal diagnosis of β-thalassemia by detection of the cell-free fetal DNA in maternal circulation: a systematic review and meta-analysis

(2016) Mandana Zafari et al.   ANNALS OF HEMATOLOGY

New strategies to target iron metabolism for the treatment of beta thalassemia

(2016) Paraskevi Rea Oikonomidou et al.   Annals of the New York Academy of Sciences

A randomized trial of amlodipine in addition to standard chelation therapy in patients with thalassemia major

(2016) J. L. Fernandes et al.   BLOOD

Hemopoietic stem cell transplantation in thalassemia: a report from the European Society for Blood and Bone Marrow Transplantation Hemoglobinopathy Registry, 2000–2010

(2016) D Baronciani et al.   BONE MARROW TRANSPLANTATION

Gene Therapy of the β-Hemoglobinopathies by Lentiviral Transfer of the βA(T87Q)-GlobinGene

(2016) Olivier Negre et al.   HUMAN GENE THERAPY

Treating hemoglobinopathies using gene-correction approaches: promises and challenges

(2016) Renee N. Cottle et al.   HUMAN GENETICS

The mutual control of iron and erythropoiesis

(2016) C. Camaschella et al.   International Journal of Laboratory Hematology

Thalassemia 2016: Modern medicine battles an ancient disease

(2015) Deborah Rund   AMERICAN JOURNAL OF HEMATOLOGY

Effects of deferasirox-deferoxamine on myocardial and liver iron in patients with severe transfusional iron overload

(2015) Yesim Aydinok et al.   BLOOD

Thalassemia major between liver and heart: Where we are now

(2015) Carlo Dessì et al.   BLOOD CELLS MOLECULES AND DISEASES

Prevalence and distribution of iron overload in patients with transfusion-dependent anemias differs across geographic regions: results from the CORDELIA study

(2015) Yesim Aydinok et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Efficacy and safety of a novel combination of two oral chelators deferasirox/deferiprone over deferoxamine/deferiprone in severely iron overloaded young beta thalassemia major patients

(2015) Mohsen S. Elalfy et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Differences in the erythropoiesis-hepcidin-iron store axis between hemoglobin H disease and  -thalassemia intermedia

(2015) R. Origa et al.   HAEMATOLOGICA

Differences in the erythropoiesis-hepcidin-iron store axis between hemoglobin H disease and  -thalassemia intermedia

(2015) R. Origa et al.   HAEMATOLOGICA

Modified activin receptor IIB ligand trap mitigates ineffective erythropoiesis and disease complications in murine  -thalassemia

(2014) R. N. V. S. Suragani et al.   BLOOD

KLF1 mutations are relatively more common in a thalassemia endemic region and ameliorate the severity of  -thalassemia

(2014) D. Liu et al.   BLOOD

Hepatocellular carcinoma in thalassaemia: an update of the Italian Registry

(2014) Caterina Borgna-Pignatti et al.   BRITISH JOURNAL OF HAEMATOLOGY

Modulators of Erythropoiesis

(2014) Laura Breda et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Deferasirox demonstrates a dose-dependent reduction in liver iron concentration and consistent efficacy across subgroups of non-transfusion-dependent thalassemia patients

(2013) Ali T. Taher et al.   AMERICAN JOURNAL OF HEMATOLOGY

Bone marrow transplantation for thalassemia from alternative related donors: improved outcomes with a new approach

(2013) J. Gaziev et al.   BLOOD

Outcome of patients with hemoglobinopathies given either cord blood or bone marrow transplantation from an HLA-identical sibling

(2013) F. Locatelli et al.   BLOOD

Clinical experience with fetal hemoglobin induction therapy in patients with  -thalassemia

(2013) K. M. Musallam et al.   BLOOD

Thalassemic erythrocytes release microparticles loaded with hemichromes by redox activation of p72Syk kinase

(2013) E. Ferru et al.   HAEMATOLOGICA

Updates of the HbVar database of human hemoglobin variants and thalassemia mutations

(2013) Belinda Giardine et al.   NUCLEIC ACIDS RESEARCH

A national registry of haemoglobinopathies in Greece: Deducted demographics, trends in mortality and affected births

(2012) Ersi Voskaridou et al.   ANNALS OF HEMATOLOGY

Oral chelators in transfusion-dependent thalassemia major patients may prevent or reverse iron overload complications

(2011) Kallistheni Farmaki et al.   BLOOD CELLS MOLECULES AND DISEASES

Optimal management of β thalassaemia intermedia

(2011) Ali T. Taher et al.   BRITISH JOURNAL OF HAEMATOLOGY

On T2* Magnetic Resonance and Cardiac Iron

(2011) John-Paul Carpenter et al.   CIRCULATION

Elevated liver iron concentration is a marker of increased morbidity in patients with   thalassemia intermedia

(2011) K. M. Musallam et al.   HAEMATOLOGICA

Beta-thalassemia: from genotype to phenotype

(2011) F. Danjou et al.   HAEMATOLOGICA

Combined iron chelation therapy

(2010) Renzo Galanello et al.   Annals of the New York Academy of Sciences

Progress in hematopoietic stem cell transplantation as allogeneic cellular gene therapy in thalassemia

(2010) Antonella Isgrò et al.   Annals of the New York Academy of Sciences

Studies in haemoglobin E beta-thalassaemia

(2010) Nancy F. Olivieri et al.   BRITISH JOURNAL OF HAEMATOLOGY

The Population Genetics and Dynamics of the Thalassemias

(2010) D.J. Weatherall et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Splenectomy and thrombosis: the case of thalassemia intermedia

(2010) A. T. TAHER et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia

(2010) Marina Cavazzana-Calvo et al.   NATURE

Beta-thalassemia

(2010) Renzo Galanello et al.   Orphanet Journal of Rare Diseases

Deferiprone Chelation Therapy for Thalassemia Major

(2009) R. Galanello et al.   ACTA HAEMATOLOGICA

Overview on practices in thalassemia intermedia management aiming for lowering complication rates across a region of endemicity: the OPTIMAL CARE study

(2009) A. T. Taher et al.   BLOOD

Cardiac T2* Magnetic Resonance for Prediction of Cardiac Complications in Thalassemia Major

(2009) P. Kirk et al.   CIRCULATION

Pregnancy and  -thalassemia: an Italian multicenter experience

(2009) R. Origa et al.   HAEMATOLOGICA

Heart Disease in Thalassemia Intermedia

(2009) A. Aessopos et al.   HEMOGLOBIN

Glutathione S-transferase gene polymorphism and cardiac iron overload in thalassaemia major

(2008) R. Origa et al.   BRITISH JOURNAL OF HAEMATOLOGY

Global epidemiology of haemoglobin disorders and derived service indicators

(2008) Bernadette Modell   BULLETIN OF THE WORLD HEALTH ORGANIZATION

Cholelithiasis in thalassemia major

(2008) Raffaella Origa et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

No evidence of cardiac iron in 20 never- or minimally-transfused patients with thalassemia intermedia

(2008) R. Origa et al.   HAEMATOLOGICA

Once-daily oral deferasirox for the treatment of transfusional iron overload

(2008) Renzo Galanello et al.   Expert Review of Clinical Pharmacology