Clinical experience with fetal hemoglobin induction therapy in patients with  -thalassemia

 -Thalassemia Intermedia: A Clinical Perspective

(2013) K. M. Musallam et al.   Cold Spring Harbor Perspectives in Medicine

A phase 1/2 trial of HQK-1001, an oral fetal globin inducer, in sickle cell disease

(2012) Abdullah Kutlar et al.   AMERICAN JOURNAL OF HEMATOLOGY

Stroke With Transfusions Changing to Hydroxyurea (SWiTCH)

(2012) R. E. Ware et al.   BLOOD

Genetic modifiers of  -thalassemia and clinical severity as assessed by age at first transfusion

(2012) F. Danjou et al.   HAEMATOLOGICA

Comparative study of hypogonadism in beta-thalassemia intermedia patients with and without hydroxyurea

(2012) Mehran Karimi et al.   Hematology

The XmnI andBCL11ASingle Nucleotide Polymorphisms May Help Predict Hydroxyurea Response in Iranian β-Thalassemia Patients

(2012) Mehdi Banan et al.   HEMOGLOBIN

Cerebral infarction in β-thalassemia intermedia: Breaking the silence

(2012) Khaled M. Musallam et al.   THROMBOSIS RESEARCH

Pomalidomide augments fetal hemoglobin production without the myelosuppressive effects of hydroxyurea in transgenic sickle cell mice

(2011) S. E. Meiler et al.   BLOOD

Fetal hemoglobin levels and morbidity in untransfused patients with  -thalassemia intermedia

(2011) K. M. Musallam et al.   BLOOD

A pilot study of subcutaneous decitabine in  -thalassemia intermedia

(2011) N. F. Olivieri et al.   BLOOD

Darbepoetin alfa for the treatment of anaemia in alpha- or beta- thalassaemia intermedia syndromes

(2011) Sylvia T. Singer et al.   BRITISH JOURNAL OF HAEMATOLOGY

Hydroxyurea for sickle cell anemia: what have we learned and what questions still remain?

(2011) Patrick T McGann et al.   CURRENT OPINION IN HEMATOLOGY

Comparative study of pulmonary circulation and myocardial function in patients with β-thalassemia intermedia with and without hydroxyurea, a case-control study

(2011) Hamid Amoozgar et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Variants in genetic modifiers of  -thalassemia can help to predict the major or intermedia type of the disease

(2011) C. Badens et al.   HAEMATOLOGICA

Interactions Of Hydroxycarbamide (Hydroxyurea) With Iron And Copper: Implications On Toxicity and Therapeutic Strategies

(2011) Eleni Konstantinou et al.   HEMOGLOBIN

Thrombosis in Thalassemia: Why are we so Concerned?

(2011) Khaled M. Musallam et al.   HEMOGLOBIN

Genotype–phenotype relationship of patients with β-thalassemia taking hydroxyurea: a 13-year experience in Iran

(2011) Mehran Karimi et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Efficacy of Hydroxyurea in Providing Transfusion Independence in β-Thalassemia

(2011) Saqib H. Ansari et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

MicroRNA-15a and -16-1 act via MYB to elevate fetal hemoglobin expression in human trisomy 13

(2011) V. G. Sankaran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adaptation to anemia in hemoglobin E-  thalassemia

(2010) A. Allen et al.   BLOOD

How I use hydroxyurea to treat young patients with sickle cell anemia

(2010) R. E. Ware   BLOOD

Desensitization to hydroxycarbamide following long-term treatment of thalassaemia intermedia as observed in vivo and in primary erythroid cultures from treated patients

(2010) Paolo Rigano et al.   BRITISH JOURNAL OF HAEMATOLOGY

Administration of high doses of recombinant human erythropoietin to patients with β-thalassemia intermedia: a preliminary trial

(2010) K. Bourantas et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Paraspinal extramedullary hematopoiesis in patients with thalassemia intermedia

(2010) Rachid Haidar et al.   EUROPEAN SPINE JOURNAL

Thalassemia: An Overview of 50 Years of Clinical Research

(2010) Vijay G. Sankaran et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Effect of hydroxyurea on the transfusion requirements in patients with severe HbE- -thalassaemia: a genotypic and phenotypic study

(2010) K. Y. Italia et al.   JOURNAL OF CLINICAL PATHOLOGY

Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin

(2010) Joseph Borg et al.   NATURE GENETICS

KLF1 regulates BCL11A expression and γ- to β-globin gene switching

(2010) Dewang Zhou et al.   NATURE GENETICS

ADVERSE EFFECTS OF HYDROXYUREA IN β-THALASSEMIA INTERMEDIA PATIENTS: 10 Years’ Experience

(2010) Mehran Karimi et al.   PEDIATRIC HEMATOLOGY AND ONCOLOGY

Chemical genetic strategy identifies histone deacetylase 1 (HDAC1) and HDAC2 as therapeutic targets in sickle cell disease

(2010) James E. Bradner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amelioration of Sardinian  0 thalassemia by genetic modifiers

(2009) R. Galanello et al.   BLOOD

Overview on practices in thalassemia intermedia management aiming for lowering complication rates across a region of endemicity: the OPTIMAL CARE study

(2009) A. T. Taher et al.   BLOOD

Differences in response to fetal hemoglobin induction therapy in β-thalassemia and sickle cell disease

(2009) Hassana Fathallah et al.   BLOOD CELLS MOLECULES AND DISEASES

Response to hydroxyurea in β thalassemia major and intermedia: Experience in western India

(2009) Khushnooma Y. Italia et al.   CLINICA CHIMICA ACTA

Effect of combination therapy of hydroxyurea with l-carnitine and magnesium chloride on hematologic parameters and cardiac function of patients with β-thalassemia intermedia

(2009) Mehran Karimi et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

A genome-wide association identified the common genetic variants influence disease severity in β0-thalassemia/hemoglobin E

(2009) Manit Nuinoon et al.   HUMAN GENETICS

HYDROXYUREA-INDUCED HEMATOLOGICAL RESPONSE IN TRANSFUSION-INDEPENDENT BETA-THALASSEMIA INTERMEDIA: Case Series and Review of Literature

(2009) Mohammad Ali Ehsani et al.   PEDIATRIC HEMATOLOGY AND ONCOLOGY

A scoring system for the classification of β-thalassemia/Hb E disease severity

(2008) Orapan Sripichai et al.   AMERICAN JOURNAL OF HEMATOLOGY

Response to hydroxyurea therapy in β-thalassemia

(2008) Ariel Koren et al.   AMERICAN JOURNAL OF HEMATOLOGY

Hydroxycarbamide-induced changes in E/beta thalassemia red blood cells

(2008) Sylvia T. Singer et al.   AMERICAN JOURNAL OF HEMATOLOGY

Thalidomide therapy in a patient with thalassemia major

(2008) Lilia Beatriz Aguilar-Lopez et al.   BLOOD CELLS MOLECULES AND DISEASES

Induction of gamma-globin gene transcription by hydroxycarbamide in primary erythroid cell cultures from Lepore patients

(2008) Roberta Calzolari et al.   BRITISH JOURNAL OF HAEMATOLOGY

Clinical effectiveness of decitabine in severe sickle cell disease

(2008) Yogen Saunthararajah et al.   BRITISH JOURNAL OF HAEMATOLOGY

Echocardiographic finding in beta-thalassemia intermedia and major: absence of pulmonary hypertension following hydroxyurea treatment in beta-thalassemia intermedia

(2008) Mehran Karimi et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

A cell stress signaling model of fetal hemoglobin induction: what doesn't kill red blood cells may make them stronger

(2008) Rodwell Mabaera et al.   EXPERIMENTAL HEMATOLOGY

Pomalidomide and lenalidomide regulate erythropoiesis and fetal hemoglobin production in human CD34+ cells

(2008) Laure A. Moutouh-de Parseval et al.   JOURNAL OF CLINICAL INVESTIGATION

Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of  -thalassemia

(2008) M. Uda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Fetal Hemoglobin Expression Is Regulated by the Developmental Stage-Specific RepressorBCL11A

(2008) Vijay G. Sankaran et al.   SCIENCE