KSHV-encoded vCyclin can modulate HIF1α levels to promote DNA replication in hypoxia

KSHV-encoded LANA protects the cellular replication machinery from hypoxia induced degradation

(2019) Rajnish Kumar Singh et al.   PLoS Pathogens

Metabolic reprogramming of Kaposi’s sarcoma associated herpes virus infected B-cells in hypoxia

(2018) Rajnish Kumar Singh et al.   PLoS Pathogens

Shugoshin 1 is dislocated by KSHV-encoded LANA inducing aneuploidy

(2018) Fengchao Lang et al.   PLoS Pathogens

Kaposi sarcoma herpesvirus-associated cancers and related diseases

(2017) Priscila H. Goncalves et al.   Current Opinion in HIV and AIDS

Hypoxia-inducible factor-1 alpha as a therapeutic target for primary effusion lymphoma

(2017) Prabha Shrestha et al.   PLoS Pathogens

Reactivation and Lytic Replication of Kaposi’s Sarcoma-Associated Herpesvirus: An Update

(2017) Kawalpreet K. Aneja et al.   Frontiers in Microbiology

Experience with Kaposi Sarcoma Herpesvirus Inflammatory Cytokine Syndrome in a Large Urban HIV Clinic in the United States: Case Series and Literature Review

(2017) Valeria D Cantos et al.   Open Forum Infectious Diseases

Primary B Lymphocytes Infected with Kaposi's Sarcoma-Associated Herpesvirus Can Be ExpandedIn Vitroand Are Recognized by LANA-Specific CD4+T Cells

(2016) Samantha M. Nicol et al.   JOURNAL OF VIROLOGY

KSHV-Mediated Regulation of Par3 and SNAIL Contributes to B-Cell Proliferation

(2016) Hem C. Jha et al.   PLoS Pathogens

Cell Cycle Regulatory Functions of the KSHV Oncoprotein LANA

(2016) Fang Wei et al.   Frontiers in Microbiology

KSHV induces aerobic glycolysis and angiogenesis through HIF-1-dependent upregulation of pyruvate kinase 2 in Kaposi’s sarcoma

(2015) Tao Ma et al.   ANGIOGENESIS

Recent advances on viral manipulation of NF-κB signaling pathway

(2015) Jun Zhao et al.   Current Opinion in Virology

Chromatinization of the KSHV Genome During the KSHV Life Cycle

(2015) Timsy Uppal et al.   Cancers

Viral Cyclin promotes KSHV-induced cellular transformation and tumorigenesis by overriding contact inhibition

(2014) Tiffany Jones et al.   CELL CYCLE

Human Viral Oncogenesis: A Cancer Hallmarks Analysis

(2014) Enrique A. Mesri et al.   Cell Host & Microbe

Herpesvirus-encoded GPCRs: neglected players in inflammatory and proliferative diseases?

(2014) Henry F. Vischer et al.   NATURE REVIEWS DRUG DISCOVERY

Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1  to promote cell-cycle progression

(2014) M. E. Hubbi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxia-inducible factor 1 and its role in viral carcinogenesis

(2014) Sean Cuninghame et al.   VIROLOGY

KSHV LANA—The Master Regulator of KSHV Latency

(2014) Timsy Uppal et al.   Viruses-Basel

Severe hypoxia induces complete antifolate resistance in carcinoma cells due to cell cycle arrest

(2014) S Raz et al.   Cell Death & Disease

KSHV 2.0: A Comprehensive Annotation of the Kaposi's Sarcoma-Associated Herpesvirus Genome Using Next-Generation Sequencing Reveals Novel Genomic and Functional Features

(2014) Carolina Arias et al.   PLoS Pathogens

Transcriptional regulation by hypoxia inducible factors

(2013) Veronica L. Dengler et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

A Nontranscriptional Role for HIF-1  as a Direct Inhibitor of DNA Replication

(2013) M. E. Hubbi et al.   Science Signaling

Kaposi Sarcoma Herpesvirus Promotes Endothelial-to-Mesenchymal Transition through Notch-Dependent Signaling

(2012) P. Gasperini et al.   CANCER RESEARCH

Oncogenic Viruses and Tumor Glucose Metabolism: Like Kids in a Candy Store

(2012) E. Noch et al.   MOLECULAR CANCER THERAPEUTICS

Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy

(2012) Gregg L. Semenza   TRENDS IN PHARMACOLOGICAL SCIENCES

Human Herpesvirus 8 Interferon Regulatory Factor-Mediated BH3-Only Protein Inhibition via Bid BH3-B Mimicry

(2012) Young Bong Choi et al.   PLoS Pathogens

Clinical Manifestations of Kaposi Sarcoma Herpesvirus Lytic Activation: Multicentric Castleman Disease (KSHV–MCD) and the KSHV Inflammatory Cytokine Syndrome

(2012) Mark N. Polizzotto et al.   Frontiers in Microbiology

Molecular Mechanisms Deployed by Virally Encoded G Protein–Coupled Receptors in Human Diseases

(2011) Silvia Montaner et al.   Annual Review of Pharmacology and Toxicology

Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen Induction by Hypoxia and Hypoxia-Inducible Factors

(2011) R. P. Veeranna et al.   JOURNAL OF VIROLOGY

Modulation of NF-κB signalling by microbial pathogens

(2011) Masmudur M. Rahman et al.   NATURE REVIEWS MICROBIOLOGY

Hypoxic activation of ATR and the suppression of the initiation of DNA replication through cdc6 degradation

(2011) L Martin et al.   ONCOGENE

Amplification of the Angiogenic Signal through the Activation of the TSC/mTOR/HIF Axis by the KSHV vGPCR in Kaposi's Sarcoma

(2011) Bruno C. Jham et al.   PLoS One

Single Molecule Analysis of Replicated DNA Reveals the Usage of Multiple KSHV Genome Regions for Latent Replication

(2011) Subhash C. Verma et al.   PLoS Pathogens

Reactive Oxygen Species Hydrogen Peroxide Mediates Kaposi's Sarcoma-Associated Herpesvirus Reactivation from Latency

(2011) Fengchun Ye et al.   PLoS Pathogens

Cell metabolism: An essential link between cell growth and apoptosis

(2010) Emily F. Mason et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor: Lessons on dysregulated angiogenesis from a viral oncogene

(2010) Bruno C. Jham et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Hypoxia-Inducible Factors and the Response to Hypoxic Stress

(2010) Amar J. Majmundar et al.   MOLECULAR CELL

Genome-wide identification of hypoxia-inducible factor binding sites and target genes by a probabilistic model integrating transcription-profiling data and in silico binding site prediction

(2010) Amaya Ortiz-Barahona et al.   NUCLEIC ACIDS RESEARCH

Cancer as a metabolic disease

(2010) Thomas N Seyfried et al.   Nutrition & Metabolism

Induction of the Warburg effect by Kaposi's sarcoma herpesvirus is required for the maintenance of latently infected endothelial cells

(2010) T. Delgado et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic Analysis of KSHV Latent and Lytic Genomes

(2010) Zsolt Toth et al.   PLoS Pathogens

HIF-1: upstream and downstream of cancer metabolism

(2009) Gregg L Semenza   CURRENT OPINION IN GENETICS & DEVELOPMENT

Early Events in Kaposi's Sarcoma-Associated Herpesvirus Infection of Target Cells

(2009) B. Chandran   JOURNAL OF VIROLOGY