In vitro selection of Remdesivir resistance suggests evolutionary predictability of SARS-CoV-2

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Mechanism of SARS-CoV-2 polymerase stalling by remdesivir

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Transmission of SARS-CoV-2 in domestic cats imposes a narrow bottleneck

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Molnupiravir promotes SARS-CoV-2 mutagenesis via the RNA template

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The furin cleavage site in the SARS-CoV-2 spike protein is required for transmission in ferrets

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Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection

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Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potency

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Compassionate Use of Remdesivir for Patients with Severe Covid-19

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An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice

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Persistent COVID-19 in an Immunocompromised Patient Temporarily Responsive to Two Courses of Remdesivir Therapy

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Mutations Strengthened SARS-CoV-2 Infectivity

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Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice

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Characterisation of the transcriptome and proteome of SARS-CoV-2 reveals a cell passage induced in-frame deletion of the furin-like cleavage site from the spike glycoprotein

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Analytical sensitivity and efficiency comparisons of SARS-CoV-2 RT–qPCR primer–probe sets

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TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells

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Effect of Remdesivir vs Standard Care on Clinical Status at 11 Days in Patients With Moderate COVID-19

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Template-dependent inhibition of coronavirus RNA-dependent RNA polymerase by remdesivir reveals a second mechanism of action

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SARS-CoV-2 growth, furin-cleavage-site adaptation and neutralization using serum from acutely infected hospitalized COVID-19 patients

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Remdesivir targets a structurally analogous region of the Ebola virus and SARS-CoV-2 polymerases

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Treatment of COVID-19 with remdesivir in the absence of humoral immunity: a case report

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Dexamethasone in hospitalised patients with COVID-19: addressing uncertainties

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Genomic epidemiology reveals multiple introductions of SARS-CoV-2 from mainland Europe into Scotland

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Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease

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Fundamental properties of the mammalian innate immune system revealed by multispecies comparison of type I interferon responses

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Coronavirus NSP6 restricts autophagosome expansion

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Coronaviruses Lacking Exoribonuclease Activity Are Susceptible to Lethal Mutagenesis: Evidence for Proofreading and Potential Therapeutics

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Mechanisms of Host Receptor Adaptation by Severe Acute Respiratory Syndrome Coronavirus

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Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

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Fast and accurate short read alignment with Burrows-Wheeler transform

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Protease-Mediated Entry via the Endosome of Human Coronavirus 229E

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