Live-cell measurements of kinase activity in single cells using translocation reporters

Multiplexed Fluorescence Imaging of ERK and Akt Activities and Cell-cycle Progression

(2016) Gembu Maryu et al.   CELL STRUCTURE AND FUNCTION

Mapping growth-factor-modulated Akt signaling dynamics

(2016) Sean M. Gross et al.   DEVELOPMENT

Reversible cryo-arrest for imaging molecules in living cells at high spatial resolution

(2016) Martin E Masip et al.   NATURE METHODS

Deep Learning Automates the Quantitative Analysis of Individual Cells in Live-Cell Imaging Experiments

(2016) David A. Van Valen et al.   PLoS Computational Biology

Akt signaling dynamics in individual cells

(2015) Sean M. Gross et al.   JOURNAL OF CELL SCIENCE

An optogenetic system for interrogating the temporal dynamics of Akt

(2015) Yoshihiro Katsura et al.   Scientific Reports

Compartmentalized AMPK Signaling Illuminated by Genetically Encoded Molecular Sensors and Actuators

(2015) Takafumi Miyamoto et al.   Cell Reports

High-Sensitivity Measurements of Multiple Kinase Activities in Live Single Cells

(2014) Sergi Regot et al.   CELL

Genetically Encoded Fluorescent Biosensors for Live-Cell Visualization of Protein Phosphorylation

(2014) Laurel Oldach et al.   CHEMISTRY & BIOLOGY

A time- and matrix-dependent TGFBR3–JUND–KRT5 regulatory circuit in single breast epithelial cells and basal-like premalignancies

(2014) Chun-Chao Wang et al.   NATURE CELL BIOLOGY

PhosphoSitePlus, 2014: mutations, PTMs and recalibrations

(2014) Peter V. Hornbeck et al.   NUCLEIC ACIDS RESEARCH

A p38 Substrate-Specific MK2-EGFP Translocation Assay for Identification and Validation of New p38 Inhibitors in Living Cells: A Comprising Alternative for Acquisition of Cellular p38 Inhibition Data

(2014) Roman Anton et al.   PLoS One

Accurate information transmission through dynamic biochemical signaling networks

(2014) J. Selimkhanov et al.   SCIENCE

Encoding and Decoding Cellular Information through Signaling Dynamics

(2013) Jeremy E. Purvis et al.   CELL

The Proliferation-Quiescence Decision Is Controlled by a Bifurcation in CDK2 Activity at Mitotic Exit

(2013) Sabrina L. Spencer et al.   CELL

Development of a FRET Biosensor with High Specificity for Akt

(2013) Haruko Miura et al.   CELL STRUCTURE AND FUNCTION

Tagging of Genomic STAT3 and STAT1 with Fluorescent Proteins and Insertion of a Luciferase Reporter in the Cyclin D1 Gene Provides a Modified A549 Cell Line to Screen for Selective STAT3 Inhibitors

(2013) Andrey Samsonov et al.   PLoS One

Phosphorylation meets nuclear import: a review

(2012) Jonathan D Nardozzi et al.   Cell Communication and Signaling

Dynamic Response Diversity of NFAT Isoforms in Individual Living Cells

(2012) Nissan Yissachar et al.   MOLECULAR CELL

Frequency-Modulated Pulses of ERK Activity Transmit Quantitative Proliferation Signals

(2012) John G. Albeck et al.   MOLECULAR CELL

Improving FRET dynamic range with bright green and red fluorescent proteins

(2012) Amy J Lam et al.   NATURE METHODS

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Quantitative analysis of cell cycle phase durations and PC12 differentiation using fluorescent biosensors

(2011) Angela T. Hahn et al.   CELL CYCLE

Detection of focal adhesion kinase activation at membrane microdomains by fluorescence resonance energy transfer

(2011) Jihye Seong et al.   Nature Communications

DNA Damage Activates a Spatially Distinct Late Cytoplasmic Cell-Cycle Checkpoint Network Controlled by MK2-Mediated RNA Stabilization

(2010) H. Christian Reinhardt et al.   MOLECULAR CELL

Single-cell NF-κB dynamics reveal digital activation and analogue information processing

(2010) Savaş Tay et al.   NATURE

Akt-RSK-S6 Kinase Signaling Networks Activated by Oncogenic Receptor Tyrosine Kinases

(2010) A. Moritz et al.   Science Signaling

Dynamics and Variability of ERK2 Response to EGF in Individual Living Cells

(2009) Cellina Cohen-Saidon et al.   MOLECULAR CELL

Making a firm decision: multifaceted regulation of cell fate in the early mouse embryo

(2009) Magdalena Zernicka-Goetz et al.   NATURE REVIEWS GENETICS

The nuts and bolts of AGC protein kinases

(2009) Laura R. Pearce et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Systematic identification of cell cycle-dependent yeast nucleocytoplasmic shuttling proteins by prediction of composite motifs

(2009) S. Kosugi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Control of cell fate by the formation of an architecturally complex bacterial community

(2008) H. Vlamakis et al.   GENES & DEVELOPMENT

Nuclear Export Signal Consensus Sequences Defined Using a Localization-Based Yeast Selection System

(2008) Shunichi Kosugi et al.   TRAFFIC

Quantitative imaging assay for NF-κB nuclear translocation in primary human macrophages

(2007) Mahdad Noursadeghi et al.   JOURNAL OF IMMUNOLOGICAL METHODS