Microglial morphology in Alzheimer’s disease and after Aβ immunotherapy

Invite Review – Understanding cause and effect in Alzheimer's pathophysiology: Implications for clinical trials

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Iba-1-/CD68+ microglia are a prominent feature of age-associated deep subcortical white matter lesions

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The relationship between the morphological subtypes of microglia and Alzheimer’s disease neuropathology

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Loss of IBA1-Expression in brains from individuals with obesity and hepatic dysfunction

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MIC‐MAC: An automated pipeline for high‐throughput characterization and classification of three‐dimensional microglia morphologies in mouse and human postmortem brain samples

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Priming Microglia for Innate Immune Memory in the Brain

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Persistent neuropathological effects 14 years following amyloid-β immunization in Alzheimer’s disease

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Molecular Mechanisms of Microglial Motility: Changes in Ageing and Alzheimer’s Disease

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Microglial motility in Alzheimer’s disease and after Aβ42 immunotherapy: a human post-mortem study

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Plaque-dependent morphological and electrophysiological heterogeneity of microglia in an Alzheimer's disease mouse model

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Systemic infection modifies the neuroinflammatory response in late stage Alzheimer’s disease

(2018) Sonja Rakic et al.   Acta Neuropathologica Communications

Microglia turnover with aging and in an Alzheimer's model via long-term in vivo single-cell imaging

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The Lifespan and Turnover of Microglia in the Human Brain

(2017) Pedro Réu et al.   Cell Reports

Coupled Proliferation and Apoptosis Maintain the Rapid Turnover of Microglia in the Adult Brain

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Pharmacological targeting of CSF1R inhibits microglial proliferation and prevents the progression of Alzheimer’s-like pathology

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Eliminating microglia in Alzheimer’s mice prevents neuronal loss without modulating amyloid-β pathology

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Microglia show altered morphology and reduced arborization in human brain during aging and Alzheimer's disease

(2016) Danielle S. Davies et al.   BRAIN PATHOLOGY

Microglial immunophenotype in dementia with Alzheimer’s pathology

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Receptors, Ion Channels, and Signaling Mechanisms Underlying Microglial Dynamics

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Colony-stimulating factor 1 receptor inhibition prevents microglial plaque association and improves cognition in 3xTg-AD mice

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Morphometric characterization of microglial phenotypes in human cerebral cortex

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Inflammatory components in human Alzheimer’s disease and after active amyloid-β42 immunization

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National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease

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Review: Activation patterns of microglia and their identification in the human brain

(2012) D. Boche et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Macrophages in Alzheimer’s disease: the blood-borne identity

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Microglial alterations in human Alzheimer's disease following Aβ42 immunization

(2010) E. Zotova et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

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