Systemic injection of AAV9 carrying a periostin promoter targets gene expression to a myofibroblast-like lineage in mouse hearts after reperfused myocardial infarction

Interacting Resident Epicardium-Derived Fibroblasts and Recruited Bone Marrow Cells Form Myocardial Infarction Scar

(2015) Adrián Ruiz-Villalba et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Cardiogenic Genes Expressed in Cardiac Fibroblasts Contribute to Heart Development and Repair

(2014) Milena B. Furtado et al.   CIRCULATION RESEARCH

Cardiac-Selective Expression of Extracellular Superoxide Dismutase After Systemic Injection of Adeno-Associated Virus 9 Protects the Heart Against Post–Myocardial Infarction Left Ventricular Remodeling

(2013) Prasad R. Konkalmatt et al.   Circulation-Cardiovascular Imaging

Induction of Cardiomyocyte-Like Cells in Infarct Hearts by Gene Transfer of Gata4, Mef2c, and Tbx5

(2012) Kohei Inagawa et al.   CIRCULATION RESEARCH

MicroRNA-Mediated In Vitro and In Vivo Direct Reprogramming of Cardiac Fibroblasts to Cardiomyocytes

(2012) Tilanthi M. Jayawardena et al.   CIRCULATION RESEARCH

Adeno-associated virus serotype 9 administered systemically after reperfusion preferentially targets cardiomyocytes in the infarct border zone with pharmacodynamics suitable for the attenuation of left ventricular remodeling

(2012) Prasad R. Konkalmatt et al.   JOURNAL OF GENE MEDICINE

Terminal Differentiation of Cardiac and Skeletal Myocytes Induces Permissivity to AAV Transduction by Relieving Inhibition Imposed by DNA Damage Response Proteins

(2012) Jasmina Lovric et al.   MOLECULAR THERAPY

In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes

(2012) Li Qian et al.   NATURE

Cardiac Regeneration from Activated Epicardium

(2012) Bram van Wijk et al.   PLoS One

A single direct injection into the left ventricular wall of an adeno-associated virus 9 (AAV9) vector expressing extracellular superoxide dismutase from the cardiac troponin-T promoter protects mice against myocardial infarction

(2011) Konkal-Matt R. Prasad et al.   JOURNAL OF GENE MEDICINE

Direct Reprogramming of Fibroblasts into Functional Cardiomyocytes by Defined Factors

(2010) Masaki Ieda et al.   CELL

Cardiac fibroblast to myofibroblast differentiation in vivo and in vitro: Expression of focal adhesion components in neonatal and adult rat ventricular myofibroblasts

(2010) Jon-Jon Santiago et al.   DEVELOPMENTAL DYNAMICS

Robust cardiomyocyte-specific gene expression following systemic injection of AAV: in vivo gene delivery follows a Poisson distribution

(2010) K-M R Prasad et al.   GENE THERAPY

microRNA122-regulated transgene expression increases specificity of cardiac gene transfer upon intravenous delivery of AAV9 vectors

(2010) A Geisler et al.   GENE THERAPY

Liver-specific microRNA-122 target sequences incorporated in AAV vectors efficiently inhibits transgene expression in the liver

(2010) C Qiao et al.   GENE THERAPY

Transduction efficiency of AAV 2/6, 2/8 and 2/9 vectors for delivering genes in human corneal fibroblasts

(2009) Ajay Sharma et al.   BRAIN RESEARCH BULLETIN

Cardiac Fibroblast

(2009) Colby A. Souders et al.   CIRCULATION RESEARCH

Origin of Cardiac Fibroblasts and the Role of Periostin

(2009) Paige Snider et al.   CIRCULATION RESEARCH

Cardiac fibroblasts are essential for the adaptive response of the murine heart to pressure overload

(2009) Norifumi Takeda et al.   JOURNAL OF CLINICAL INVESTIGATION

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Neonatal and Adult Cardiovascular Pathophysiological Remodeling and Repair

(2008) Russell A. Norris et al.   Annals of the New York Academy of Sciences

Processing of recombinant AAV genomes occurs in specific nuclear structures that overlap with foci of DNA-damage-response proteins

(2008) T. Cervelli et al.   JOURNAL OF CELL SCIENCE

Periostin is essential for cardiac healingafter acute myocardial infarction

(2008) Masashi Shimazaki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Analysis of AAV Serotypes 1–9 Mediated Gene Expression and Tropism in Mice After Systemic Injection

(2008) Carmela Zincarelli et al.   MOLECULAR THERAPY