Xenotransplantation of tannic acid‐encapsulated neonatal porcine islets decreases proinflammatory innate immune responses

Co‐transplantation of human adipose‐derived mesenchymal stem cells with neonatal porcine islets within a prevascularized subcutaneous space augments the xenograft function

(2020) Purushothaman Kuppan et al.   XENOTRANSPLANTATION

Localized Immunosuppression with Tannic Acid Encapsulation Delays Islet Allograft and Autoimmune-Mediated Rejection

(2020) Jessie M. Barra et al.   DIABETES

Potential pathological role of pro-inflammatory cytokines (IL-6, TNF-α, and IL-17) in xenotransplantation

(2019) Yanli Zhao et al.   XENOTRANSPLANTATION

The Immunoreactive Platform of the Pancreatic Islets Influences the Development of Autoreactivity

(2019) Emil R. Unanue et al.   DIABETES

Scavenging reactive oxygen species selectively inhibits M2 macrophage polarization and their pro-tumorigenic function in part, via Stat3 suppression

(2019) Brandon Griess et al.   FREE RADICAL BIOLOGY AND MEDICINE

Clinical islet transplantation

(2018) Andrew R. Pepper et al.   Current Opinion in Organ Transplantation

Functional maturation and in vitro differentiation of neonatal porcine islet grafts

(2018) Tarek Hassouna et al.   TRANSPLANTATION

Report of the Key Opinion Leaders Meeting on Stem Cell-Derived Beta Cells

(2018) Jon Odorico et al.   TRANSPLANTATION

Redox-Dependent Inflammation in Islet Transplantation Rejection

(2018) Jessie M. Barra et al.   Frontiers in Endocrinology

Alginate encapsulation as long-term immune protection of allogeneic pancreatic islet cells transplanted into the omental bursa of macaques

(2018) Matthew A. Bochenek et al.   Nature Biomedical Engineering

Reactive oxygen species (ROS) in macrophage activation and function in diabetes

(2018) Erika Rendra et al.   IMMUNOBIOLOGY

Bio-based materials with novel characteristics for tissue engineering applications – A review

(2017) Luis Bedian et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Pancreatic islet inflammation: an emerging role for chemokines

(2017) J Jason Collier et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9

(2017) Dong Niu et al.   SCIENCE

Redox-Sensitive Innate Immune Pathways During Macrophage Activation in Type 1 Diabetes

(2017) Ashley R. Burg et al.   ANTIOXIDANTS & REDOX SIGNALING

Modifying the sugar icing on the transplantation cake

(2016) David K C Cooper   GLYCOBIOLOGY

Clinical pancreatic islet transplantation

(2016) A. M. James Shapiro et al.   Nature Reviews Endocrinology

The Reactive Oxygen Species in Macrophage Polarization: Reflecting Its Dual Role in Progression and Treatment of Human Diseases

(2016) Hor-Yue Tan et al.   Oxidative Medicine and Cellular Longevity

The pathobiology of pig-to-primate xenotransplantation: a historical review

(2016) David K.C. Cooper et al.   XENOTRANSPLANTATION

Antiaging Glycopeptide Protects Human Islets Against Tacrolimus-Related Injury and Facilitates Engraftment in Mice

(2015) Boris L. Gala-Lopez et al.   DIABETES

Heme Oxygenase-1 Induction Prevents Autoimmune Diabetes in Association With Pancreatic Recruitment of M2-Like Macrophages, Mesenchymal Cells, and Fibrocytes

(2015) Mahmoud Husseini et al.   ENDOCRINOLOGY

Role of transcription factors in the transdifferentiation of pancreatic islet cells

(2015) T. van der Meulen et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Treatment of diabetes with encapsulated pig islets: an update on current developments

(2015) Hai-tao Zhu et al.   Journal of Zhejiang University-SCIENCE B

A prevascularized subcutaneous device-less site for islet and cellular transplantation

(2015) Andrew R Pepper et al.   NATURE BIOTECHNOLOGY

Novel Markers to Delineate Murine M1 and M2 Macrophages

(2015) Kyle A. Jablonski et al.   PLoS One

Pig-to-Monkey Islet Xenotransplantation Using Multi-Transgenic Pigs

(2014) R. Bottino et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Loss of NADPH Oxidase–Derived Superoxide Skews Macrophage Phenotypes to Delay Type 1 Diabetes

(2014) Lindsey E. Padgett et al.   DIABETES

Oxidative stress and susceptibility to mitochondrial permeability transition precedes the onset of diabetes in autoimmune non-obese diabetic mice

(2014) C. Malaguti et al.   FREE RADICAL RESEARCH

Hydrogen-Bonded Multilayers of Tannic Acid as Mediators of T-Cell Immunity

(2014) Veronika Kozlovskaya et al.   Advanced Healthcare Materials

Pure curcumin increases the expression of SOCS1 and SOCS3 in myeloproliferative neoplasms through suppressing class Ι histone deacetylases

(2013) Chi-qi Chen et al.   CARCINOGENESIS

Inactivation of specific β cell transcription factors in type 2 diabetes

(2013) Shuangli Guo et al.   JOURNAL OF CLINICAL INVESTIGATION

Ultrathin Polymeric Coatings Based on Hydrogen-Bonded Polyphenol for Protection of Pancreatic Islet Cells

(2012) Veronika Kozlovskaya et al.   ADVANCED FUNCTIONAL MATERIALS

Adoptive Transfer of Immunomodulatory M2 Macrophages Prevents Type 1 Diabetes in NOD Mice

(2012) R. Parsa et al.   DIABETES

Trends in childhood type 1 diabetes incidence in Europe during 1989–2008: evidence of non-uniformity over time in rates of increase

(2012) C. C. Patterson et al.   DIABETOLOGIA

Dysregulated TLR3-dependent signaling and innate immune activation in superoxide-deficient macrophages from nonobese diabetic mice

(2012) Maria C. Seleme et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondria-targeted Antioxidants Protect Pancreatic β-cells against Oxidative Stress and Improve Insulin Secretion in Glucotoxicity and Glucolipotoxicity

(2011) Sangbin Lim et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Expression and Regulation of Chemokines in Murine and Human Type 1 Diabetes

(2011) S. A. Sarkar et al.   DIABETES

Redox Modulation Protects Islets From Transplant-Related Injury

(2010) M. M. Sklavos et al.   DIABETES

NOX2 Deficiency Protects Against Streptozotocin-Induced  -Cell Destruction and Development of Diabetes in Mice

(2010) F.-L. Xiang et al.   DIABETES

Islet amyloid deposition limits the viability of human islet grafts but not porcine islet grafts

(2010) K. J. Potter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Redox Regulation of Tumor Necrosis Factor Signaling

(2009) Derick Han et al.   ANTIOXIDANTS & REDOX SIGNALING