Hepatotoxic potentials of methotrexate: Understanding the possible toxicological molecular mechanisms
出版年份 2021 全文链接
标题
Hepatotoxic potentials of methotrexate: Understanding the possible toxicological molecular mechanisms
作者
关键词
Methotrexate, Drug induced liver injury, Psoriasis, Rheumatoid arthritis
出版物
TOXICOLOGY
Volume 458, Issue -, Pages 152840
出版商
Elsevier BV
发表日期
2021-06-25
DOI
10.1016/j.tox.2021.152840
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Boldine treatment protects acetaminophen‐induced liver inflammation and acute hepatic necrosis in mice
- (2021) Devaraj Ezhilarasan et al. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
- Nrf2: a main responsive element in cells to mycotoxin-induced toxicity
- (2021) Marta Justyna Kozieł et al. ARCHIVES OF TOXICOLOGY
- Drug-induced liver injury: Asia Pacific Association of Study of Liver consensus guidelines
- (2021) Harshad Devarbhavi et al. Hepatology International
- Methotrexate and its mechanisms of action in inflammatory arthritis
- (2020) Bruce N. Cronstein et al. Nature Reviews Rheumatology
- β-Sitosterol attenuates carbon tetrachloride–induced oxidative stress and chronic liver injury in rats
- (2020) Ezhilarasan Devaraj et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Naringin alleviates methotrexate-induced liver injury in male albino rats and enhances its antitumor efficacy in HepG2 cells
- (2020) Hany Elsawy et al. BIOSCIENCE REPORTS
- Chicoric acid prevents methotrexate hepatotoxicity via attenuation of oxidative stress and inflammation and up-regulation of PPARγ and Nrf2/HO-1 signaling
- (2020) Omnia E. Hussein et al. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
- Overview of Dual-Acting Drug Methotrexate in Different Neurological Diseases, Autoimmune Pathologies and Cancers
- (2020) Przemysław Koźmiński et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- STAT3: A key regulator in liver fibrosis
- (2020) Jie Zhao et al. Annals of Hepatology
- Ginkgo biloba Extract Protects against Methotrexate-Induced Hepatotoxicity: A Computational and Pharmacological Approach
- (2020) Lina Tariq Al Kury et al. MOLECULES
- MicroRNA interplay between hepatic stellate cell quiescence and activation
- (2020) Devaraj Ezhilarasan EUROPEAN JOURNAL OF PHARMACOLOGY
- Endothelin-1 in portal hypertension: The intricate role of hepatic stellate cells
- (2020) Devaraj Ezhilarasan EXPERIMENTAL BIOLOGY AND MEDICINE
- Protective effects of apigenin on altered lipid peroxidation, inflammation, and antioxidant factors in methotrexate-induced hepatotoxicity
- (2020) Mehdi Goudarzi et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Hepatoprotective effect of Ginkgo biloba extract against methotrexate-induced hepatotoxicity via targeting STAT3/miRNA-21 axis
- (2020) Iman O. Sherif et al. DRUG AND CHEMICAL TOXICOLOGY
- Protective effects of Glycyrrhiza glabra supplementation against methotrexate-induced hepato-renal damage in rats: An experimental approach
- (2020) Prerna Chauhan et al. JOURNAL OF ETHNOPHARMACOLOGY
- An Overview of Nrf2 Signaling Pathway and Its Role in Inflammation
- (2020) Sarmistha Saha et al. MOLECULES
- Acetaminophen Hepatotoxicity
- (2019) Anup Ramachandran et al. SEMINARS IN LIVER DISEASE
- Drug-Induced Acute-on-Chronic Liver Failure in Asian Patients
- (2019) Harshad Devarbhavi et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Low-dose methotrexate toxicity
- (2019) Kevin Pivovarov et al. CANADIAN MEDICAL ASSOCIATION JOURNAL
- Methotrexate treatment in rheumatoid arthritis and elevated liver enzymes: A long‐term follow‐up of predictors, surveillance, and outcome in clinical practice
- (2019) Johanna Karlsson Sundbaum et al. International Journal of Rheumatic Diseases
- Drug-induced liver injury
- (2019) Raul J. Andrade et al. Nature Reviews Disease Primers
- Dapsone-induced hepatic complications: it’s time to think beyond methemoglobinemia
- (2019) Devaraj Ezhilarasan DRUG AND CHEMICAL TOXICOLOGY
- Liver Abnormalities in Patients with Psoriatic Arthritis
- (2019) Rattapol Pakchotanon et al. JOURNAL OF RHEUMATOLOGY
- Ellagic acid reduces methotrexate-induced apoptosis and mitochondrial dysfunction via up-regulating Nrf2 expression and inhibiting the IĸBα/NFĸB in rats
- (2019) Reihaneh Ebrahimi et al. DARU-Journal of Pharmaceutical Sciences
- Ferulic acid prevents oxidative stress, inflammation, and liver injury via upregulation of Nrf2/HO-1 signaling in methotrexate-induced rats
- (2019) Ayman M. Mahmoud et al. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
- Concomitant febuxostat enhances methotrexate-induced hepatotoxicity by inhibiting breast cancer resistance protein
- (2019) Kenji Ikemura et al. Scientific Reports
- Accuracy of the Enhanced Liver Fibrosis Test vs FibroTest, Elastography, and Indirect Markers in Detection of Advanced Fibrosis in Patients With Alcoholic Liver Disease
- (2018) Maja Thiele et al. GASTROENTEROLOGY
- Hepatic fibrosis: It is time to go with hepatic stellate cell-specific therapeutic targets
- (2018) Devaraj Ezhilarasan et al. Hepatobiliary & Pancreatic Diseases International
- Psoriatic patients with chronic viral hepatitis do not have an increased risk of liver cirrhosis despite long-term methotrexate use: real-world data from a nationwide cohort study in Taiwan.
- (2018) Kuo-Tung Tang et al. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
- Risk factors for abnormal hepatic enzyme elevation by methotrexate treatment in patients with rheumatoid arthritis: A hospital based-cohort study
- (2018) Jun Hakamata et al. Modern Rheumatology
- Antioxidant response elements: Discovery, classes, regulation and potential applications
- (2018) Azhwar Raghunath et al. Redox Biology
- Oxidative stress is bane in chronic liver diseases: Clinical and experimental perspective
- (2018) Devaraj Ezhilarasan Arab Journal of Gastroenterology
- Methotrexate mechanism in treatment of rheumatoid arthritis
- (2018) Benjamin Friedman et al. JOINT BONE SPINE
- Burden of Liver Diseases in the World
- (2018) Sumeet K. Asrani et al. JOURNAL OF HEPATOLOGY
- Non-alcoholic steatohepatitis-like pattern in liver biopsy of rheumatoid arthritis patients with persistent transaminitis during low-dose methotrexate treatment
- (2018) Shunsuke Mori et al. PLoS One
- Roles of the immune system in cancer: from tumor initiation to metastatic progression
- (2018) Hugo Gonzalez et al. GENES & DEVELOPMENT
- Association between cumulative methotrexate dose, non-invasive scoring system and hepatic fibrosis detected by Fibroscan in rheumatoid arthritis patients receiving methotrexate
- (2018) Ratchaya Lertnawapan et al. International Journal of Rheumatic Diseases
- Validation of the Fibrosis-4 (FIB-4) index in the diagnosis of liver disease of rheumatoid arthritis patients treated with methotrexate
- (2018) Masayuki Miyata et al. Modern Rheumatology
- Drug-induced liver injury: recent advances in diagnosis and risk assessment
- (2017) Gerd A Kullak-Ublick et al. GUT
- Drug-induced acute liver failure in children and adults: Results of a single-centre study of 128 patients
- (2017) Harshad Devarbhavi et al. LIVER INTERNATIONAL
- Hepatoprotective effect of sitagliptin against methotrexate induced liver toxicity
- (2017) Hany M. Abo-Haded et al. PLoS One
- The Australasian Psoriasis Collaboration view on methotrexate for psoriasis in the Australasian setting
- (2016) Marius Rademaker et al. AUSTRALASIAN JOURNAL OF DERMATOLOGY
- Mechanism of action of methotrexate in rheumatoid arthritis and the search for biomarkers
- (2016) Philip M. Brown et al. Nature Reviews Rheumatology
- Effect of captopril and telmisartan on methotrexate-induced hepatotoxicity in rats: impact of oxidative stress, inflammation and apoptosis
- (2016) Mina T Kelleni et al. TOXICOLOGY MECHANISMS AND METHODS
- Methotrexate is not associated with increased liver cirrhosis in a population-based cohort of rheumatoid arthritis patients with chronic hepatitis B
- (2016) Kuo-Tung Tang et al. Scientific Reports
- Folylpolyglutamate synthase is a major determinant of intracellular methotrexate polyglutamates in patients with rheumatoid arthritis
- (2016) Tatsuhiro Yamamoto et al. Scientific Reports
- Effect of captopril and telmisartan on methotrexate-induced hepatotoxicity in rats: impact of oxidative stress, inflammation and apoptosis
- (2016) Mina T Kelleni et al. TOXICOLOGY MECHANISMS AND METHODS
- Methotrexate-related Primary Hepatic Lymphoma in a Patient with Rheumatoid Arthritis
- (2015) Koichiro Miyagawa et al. INTERNAL MEDICINE
- Protective effect of infliximab on methotrexate-induced liver injury in rats: Unexpected drug interaction
- (2015) Erkan Cure et al. Journal of Cancer Research and Therapeutics
- Methotrexate polyglutamates as a potential marker of adherence to long-term therapy in children with juvenile idiopathic arthritis and juvenile dermatomyositis: an observational, cross-sectional study
- (2015) Ahmed F. Hawwa et al. ARTHRITIS RESEARCH & THERAPY
- Validity of noninvasive markers of methotrexate-induced hepatotoxicity: a retrospective cohort study
- (2014) C.L. Martyn-Simmons et al. BRITISH JOURNAL OF DERMATOLOGY
- Autoimmune hepatitis as an adverse effect of long-term methotrexate therapy
- (2014) Kamilia Ksouda et al. INDIAN JOURNAL OF PHARMACOLOGY
- Drug-Induced Liver Injury
- (2014) Michael D. Leise et al. MAYO CLINIC PROCEEDINGS
- Biomarkers for methotrexate-induced liver injury: Urinary protein profiling of psoriasis patients
- (2013) Rachel P.L. van Swelm et al. TOXICOLOGY LETTERS
- Genetic risk factors for drug-induced liver injury in rheumatoid arthritis patients using low-dose methotrexate
- (2012) Cristina Lucía Dávila-Fajardo et al. PHARMACOGENOMICS
- Increased sensitivity to apoptosis induced by methotrexate is mediated by JNK
- (2011) Charles F. Spurlock et al. ARTHRITIS AND RHEUMATISM
- Protective role of taurine against genotoxic damage in mice treated with methotrexate and tamoxfine
- (2010) Sally S. Alam et al. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
- Multinational evidence-based recommendations for the use of methotrexate in rheumatic disorders with a focus on rheumatoid arthritis: integrating systematic literature research and expert opinion of a broad international panel of rheumatologists in the 3E Initiative
- (2008) K Visser et al. ANNALS OF THE RHEUMATIC DISEASES
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