Perturbation of ribosomal subunit dynamics by inhibitors of tRNA translocation

The structural basis for inhibition of ribosomal translocation by viomycin

(2020) Ling Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the bacterial ribosome at 2 Å resolution

(2020) Zoe L Watson et al.   eLife

Converting GTP hydrolysis into motion: versatile translational elongation factor G

(2019) Marina V. Rodnina et al.   BIOLOGICAL CHEMISTRY

Active role of elongation factor G in maintaining the mRNA reading frame during translation

(2019) Bee-Zen Peng et al.   Science Advances

Roles of specific aminoglycoside–ribosome interactions in the inhibition of translation

(2018) Lanqing Ying et al.   RNA

The ribosome moves: RNA mechanics and translocation

(2017) Harry F Noller et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ribosome structural dynamics in translocation: yet another functional role for ribosomal RNA

(2017) Harry F. Noller et al.   QUARTERLY REVIEWS OF BIOPHYSICS

The ribosome moves: RNA mechanics and translocation

(2017) Harry F Noller et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Effect of Fusidic Acid on the Kinetics of Molecular Motions During EF-G-Induced Translocation on the Ribosome

(2017) Riccardo Belardinelli et al.   Scientific Reports

Multiperspective smFRET reveals rate-determining late intermediates of ribosomal translocation

(2016) Michael R Wasserman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Choreography of molecular movements during ribosome progression along mRNA

(2016) Riccardo Belardinelli et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Translocation as continuous movement through the ribosome

(2016) Riccardo Belardinelli et al.   RNA Biology

Multiperspective smFRET reveals rate-determining late intermediates of ribosomal translocation

(2016) Michael R Wasserman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Choreography of molecular movements during ribosome progression along mRNA

(2016) Riccardo Belardinelli et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Kinetics of Spontaneous and EF-G-Accelerated Rotation of Ribosomal Subunits

(2016) Heena Sharma et al.   Cell Reports

Chemically related 4,5-linked aminoglycoside antibiotics drive subunit rotation in opposite directions

(2015) Michael R. Wasserman et al.   Nature Communications

GTP hydrolysis by EF-G synchronizes tRNA movement on small and large ribosomal subunits

(2014) W. Holtkamp et al.   EMBO JOURNAL

Fusidic Acid Targets Elongation Factor G in Several Stages of Translocation on the Bacterial Ribosome

(2014) Anneli Borg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Following movement of domain IV of elongation factor G during ribosomal translocation

(2014) Enea Salsi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular mechanics of 30S subunit head rotation

(2014) Srividya Mohan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How the ribosome hands the A-site tRNA to the P site during EF-G-catalyzed translocation

(2014) J. Zhou et al.   SCIENCE

Ribosome-targeting antibiotics and mechanisms of bacterial resistance

(2013) Daniel N. Wilson   NATURE REVIEWS MICROBIOLOGY

Visualization of two transfer RNAs trapped in transit during elongation factor G-mediated translocation

(2013) D. J. F. Ramrath et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A structural basis for streptomycin-induced misreading of the genetic code

(2013) Hasan Demirci et al.   Nature Communications

The Impact of Aminoglycosides on the Dynamics of Translation Elongation

(2013) Albert Tsai et al.   Cell Reports

Unraveling the dynamics of ribosome translocation

(2012) Jin Chen et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

The Antibiotic Thermorubin Inhibits Protein Synthesis by Binding to Inter-Subunit Bridge B2a of the Ribosome

(2012) David Bulkley et al.   JOURNAL OF MOLECULAR BIOLOGY

Allosteric control of the ribosome by small-molecule antibiotics

(2012) Leyi Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Following the intersubunit conformation of the ribosome during translation in real time

(2010) Colin Echeverría Aitken et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome

(2010) Robin E Stanley et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The A–Z of bacterial translation inhibitors

(2009) Daniel N. Wilson   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Aminoglycoside activity observed on single pre-translocation ribosome complexes

(2009) Michael B Feldman et al.   Nature Chemical Biology

Spontaneous Intersubunit Rotation in Single Ribosomes

(2008) Peter V. Cornish et al.   MOLECULAR CELL

Structural basis for hygromycin B inhibition of protein biosynthesis

(2008) M. A. Borovinskaya et al.   RNA