Inactivation of the tumor suppressor p53 by long noncoding RNA RMRP

Inactivating p53 is essential for nerve growth factor receptor to promote melanoma-initiating cell-stemmed tumorigenesis

(2020) Leiwei Jiang et al.   Cell Death & Disease

Lnc‐ RMRP is involved in the progression of cholangiocarcinoma by regulating miR‐217

(2019) Lingyu Tang et al.   CANCER SCIENCE

A decade of clinical development of PARP inhibitors in perspective

(2019) J Mateo et al.   ANNALS OF ONCOLOGY

Ubiquitin ligase TRIM71 suppresses ovarian tumorigenesis by degrading mutant p53

(2019) Yajie Chen et al.   Cell Death & Disease

Synthetic Lethality of PARP Inhibition and Ionizing Radiation is p53-dependent

(2018) Steven T. Sizemore et al.   MOLECULAR CANCER RESEARCH

GUARDIN is a p53-responsive long non-coding RNA that is essential for genomic stability

(2018) Wang Lai Hu et al.   NATURE CELL BIOLOGY

The coming of age of chaperone-mediated autophagy

(2018) Susmita Kaushik et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Metabolic regulation of transcription through compartmentalized NAD+biosynthesis

(2018) Keun Woo Ryu et al.   SCIENCE

c-Myc, RMRP, and miR-34a-5p form a positive-feedback loop to regulate cell proliferation and apoptosis in multiple myeloma

(2018) Xichun Xiao et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Targeted CRISPR disruption reveals a role for RNase MRP RNA in human preribosomal RNA processing

(2017) Katherine C. Goldfarb et al.   GENES & DEVELOPMENT

PARP-1 Controls the Adipogenic Transcriptional Program by PARylating C/EBPβ and Modulating Its Transcriptional Activity

(2017) Xin Luo et al.   MOLECULAR CELL

Recurrent and functional regulatory mutations in breast cancer

(2017) Esther Rheinbay et al.   NATURE

The C-terminal domain of p53 orchestrates the interplay between non-covalent and covalent poly(ADP-ribosyl)ation of p53 by PARP1

(2017) Arthur Fischbach et al.   NUCLEIC ACIDS RESEARCH

The unique spliceosome signature of human pluripotent stem cells is mediated by SNRPA1, SNRPD1, and PNN

(2017) Young-Dae Kim et al.   Stem Cell Research

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Long Noncoding RNAs in Cancer Pathways

(2016) Adam M. Schmitt et al.   CANCER CELL

p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity

(2016) Carmen Adriaens et al.   NATURE MEDICINE

Major spliceosome defects cause male infertility and are associated with nonobstructive azoospermia in humans

(2016) Hao Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pleckstrin homology domain-containing protein PHLDB3 supports cancer growth via a negative feedback loop involving p53

(2016) Tengfei Chao et al.   Nature Communications

LncRNA-RMRP promotes carcinogenesis by acting as a miR-206 sponge and is used as a novel biomarker for gastric cancer

(2016) Yongfu Shao et al.   Oncotarget

Nerve growth factor receptor negates the tumor suppressor p53 as a feedback regulator

(2016) Xiang Zhou et al.   eLife

Small PARP inhibitor PJ-34 induces cell cycle arrest and apoptosis of adult T-cell leukemia cells

(2015) Xue Tao Bai et al.   Journal of Hematology & Oncology

Ribosomal proteins: functions beyond the ribosome

(2015) Xiang Zhou et al.   Journal of Molecular Cell Biology

New Insights into PARP Inhibitors' Effect on Cell Cycle and Homology-Directed DNA Damage Repair

(2014) P. Jelinic et al.   MOLECULAR CANCER THERAPEUTICS

Role of the lncRNA-p53 regulatory network in cancer

(2014) A. Zhang et al.   Journal of Molecular Cell Biology

Mutant p53: one name, many proteins

(2012) W. A. Freed-Pastor et al.   GENES & DEVELOPMENT

Signaling to p53: Ribosomal Proteins Find Their Way

(2009) Yanping Zhang et al.   CANCER CELL

Mdm2 Regulates p53 mRNA Translation through Inhibitory Interactions with Ribosomal Protein L26

(2008) Yaara Ofir-Rosenfeld et al.   MOLECULAR CELL