标题
Honokiol: A review of its pharmacological potential and therapeutic insights
作者
关键词
Honokiol, Magnolol, Anti-inflammatory, Antioxidant, Meuroprotective
出版物
PHYTOMEDICINE
Volume 90, Issue -, Pages 153647
出版商
Elsevier BV
发表日期
2021-07-16
DOI
10.1016/j.phymed.2021.153647
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Honokiol induces endoplasmic reticulum stress-mediated apoptosis in human lung cancer cells
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- Honokiol alleviates sepsis-induced acute kidney injury in mice by targeting the miR-218-5p/heme oxygenase-1 signaling pathway
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- Formylated honokiol analogs showed antitumor activity against lung carcinoma
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- Honokiol Alleviates Oxidative Stress-Induced Neurotoxicity via Activation of Nrf2
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- Honokiol protects pancreatic β cell against high glucose and intermittent hypoxia-induced injury by activating Nrf2/ARE pathway in vitro and in vivo
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- Honokiol protects hepatocytes from oxidative injury through mitochondrial deacetylase SIRT3
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- Honokiol attenuates diet-induced non-alcoholic steatohepatitis by regulating macrophage polarization through activating peroxisome proliferator-activated receptor γ
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- Honokiol Improves Liver Steatosis in Ovariectomized Mice
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- Exploiting Honokiol-induced ER stress CHOP activation inhibits the growth and metastasis of melanoma by suppressing the MITF and β-catenin pathways
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- Honokiol, a potential therapeutic agent, induces cell cycle arrest and program cell death in vitro and in vivo in human thyroid cancer cells
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- Honokiol, an activator of Sirtuin-3 (SIRT3) preserves mitochondria and protects the heart from doxorubicin-induced cardiomyopathy in mice
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- Honokiol inhibits c-Met-HO-1 tumor-promoting pathway and its cross-talk with calcineurin inhibitor-mediated renal cancer growth
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- Honokiol suppresses formyl peptide-induced human neutrophil activation by blocking formyl peptide receptor 1
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- Honokiol inhibits ultraviolet radiation-induced immunosuppression through inhibition of ultraviolet-induced inflammation and DNA hypermethylation in mouse skin
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- Chemopreventive Activity of Honokiol against 7, 12 - Dimethylbenz[a]anthracene-Induced Mammary Cancer in Female Sprague Dawley Rats
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- Honokiol Induces Apoptosis, G1 Arrest, and Autophagy in KRAS Mutant Lung Cancer Cells
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- Honokiol protects against doxorubicin cardiotoxicity via improving mitochondrial function in mouse hearts
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- Honokiol inhibits EMT-mediated motility and migration of human non-small cell lung cancer cells in vitro by targeting c-FLIP
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- Honokiol suppresses pancreatic tumor growth, metastasis and desmoplasia by interfering with tumor–stromal cross-talk
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- Regulation of Mucin 1 and multidrug resistance protein 1 by honokiol enhances the efficacy of doxorubicin-mediated growth suppression in mammary carcinoma cells
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- Honokiol inhibits migration of renal cell carcinoma through activation of RhoA/ROCK/MLC signaling pathway
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- In vitroantimicrobial activity of honokiol againstStaphylococcus aureusin biofilm mode
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- Evidences of Herbal Medicine-Derived Natural Products Effects in Inflammatory Lung Diseases
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- Anti-biofilm and bactericidal effects of magnolia bark-derived magnolol and honokiol on Streptococcus mutans
- (2016) Yuuki Sakaue et al. MICROBIOLOGY AND IMMUNOLOGY
- Pro-Apoptotic Activity of New Honokiol/Triphenylmethane Analogues in B-Cell Lymphoid Malignancies
- (2016) Aleksandra Mędra et al. MOLECULES
- Honokiol induces autophagic cell death in malignant glioma through reactive oxygen species-mediated regulation of the p53/PI3K/Akt/mTOR signaling pathway
- (2016) Chien-Ju Lin et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Honokiol suppresses lung tumorigenesis by targeting EGFR and its downstream effectors
- (2016) Jung Min Song et al. Oncotarget
- Honokiol suppresses TNF-α-induced neutrophil adhesion on cerebral endothelial cells by disrupting polyubiquitination and degradation of IκBα
- (2016) Po-Jen Chen et al. Scientific Reports
- Multifunctional effects of honokiol as an anti-inflammatory and anti-cancer drug in human oral squamous cancer cells and xenograft
- (2015) Jin Hyoung Cho et al. BIOMATERIALS
- In vitro synergism of magnolol and honokiol in combination with antibacterial agents against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA)
- (2015) Guo-Ying Zuo et al. BMC Complementary and Alternative Medicine
- Magnolol and honokiol regulate the calcium-activated potassium channels signaling pathway in Enterotoxigenic Escherichia coli-induced diarrhea mice
- (2015) Yanli Deng et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Effect of honokiol on exotoxin proteins listeriolysin O and p60 secreted by Listeria monocytogenes
- (2015) Rizeng Meng et al. JOURNAL OF MEDICAL MICROBIOLOGY
- Honokiol protects against renal ischemia/reperfusion injury via the suppression of oxidative stress, iNOS, inflammation and STAT3 in rats
- (2015) YONGWU YU et al. Molecular Medicine Reports
- Beneficial effect of honokiol on lipopolysaccharide induced anxiety-like behavior and liver damage in mice
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- Honokiol Downregulates Kruppel-Like Factor 4 Expression, Attenuates Inflammation, and Reduces Histopathology After Spinal Cord Injury in Rats
- (2015) Jia Liu et al. SPINE
- Honokiol activates the LKB1–AMPK signaling pathway and attenuates the lipid accumulation in hepatocytes
- (2015) Min Suk Seo et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Honokiol, a Lignan Biphenol Derived from the Magnolia Tree, Inhibits Dengue Virus Type 2 Infection
- (2015) Chih-Yeu Fang et al. Viruses-Basel
- Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3
- (2015) Vinodkumar B. Pillai et al. Nature Communications
- Antimicrobial Effects and Resistant Regulation of Magnolol and Honokiol on Methicillin-ResistantStaphylococcus aureus
- (2015) Su Young Kim et al. Biomed Research International
- Honokiol abrogates lipopolysaccharide-induced depressive like behavior by impeding neuroinflammation and oxido-nitrosative stress in mice
- (2014) Kunjbihari Sulakhiya et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Recent Progress on Liver Kinase B1 (LKB1): Expression, Regulation, Downstream Signaling and Cancer Suppressive Function
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- Honokiol trimers and dimers via biotransformation catalyzed by Momordica charantia peroxidase: Novel and potent α-glucosidase inhibitors
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- Mitochondrial Localized Stat3 Promotes Breast Cancer Growth via Phosphorylation of Serine 727
- (2013) Qifang Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Honokiol, a low molecular weight natural product, prevents inflammatory response and cartilage matrix degradation in human osteoarthritis chondrocytes
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- Long-term supplementation of honokiol and magnolol ameliorates body fat accumulation, insulin resistance, and adipose inflammation in high-fat fed mice
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- Honokiol and magnolol stimulate glucose uptake by activating PI3K-dependent Akt in L6 myotubes
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- Honokiol suppresses the development of post-ischemic glucose intolerance and neuronal damage in mice
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- Honokiol inhibits the inflammatory reaction during cerebral ischemia reperfusion by suppressing NF-κB activation and cytokine production of glial cells
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- Ethanol Extract ofMagnolia officinalisPrevents Lipopolysaccharide-Induced Memory Deficiency via Its Antineuroinflammatory and Antiamyloidogenic Effects
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- Honokiol Attenuates Torsion/Detorsion-induced Testicular Injury in Rat Testis by Way of Suppressing Endoplasmic Reticulum Stress-related Apoptosis
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- Honokiol protects rat hearts against myocardial ischemia reperfusion injury by reducing oxidative stress and inflammation
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- Honokiol ameliorates renal fibrosis by inhibiting extracellular matrix and pro-inflammatory factors in vivo and in vitro
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- Honokiol rescues sepsis-associated acute lung injury and lethality via the inhibition of oxidative stress and inflammation
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- Honokiol enhances adipocyte differentiation by potentiating insulin signaling in 3T3-L1 preadipocytes
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- Magnolia dealbata Zucc and its active principles honokiol and magnolol stimulate glucose uptake in murine and human adipocytes using the insulin-signaling pathway
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- Honokiol, a phytochemical from the Magnolia plant, inhibits photocarcinogenesis by targeting UVB-induced inflammatory mediators and cell cycle regulators: development of topical formulation
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- Honokiol inhibits H2O2-induced apoptosis in human lens epithelial cells via inhibition of the mitogen-activated protein kinase and Akt pathways
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- Anti-Inflammatory Bioactivities of Honokiol through Inhibition of Protein Kinase C, Mitogen-Activated Protein Kinase, and the NF-κB Pathway To Reduce LPS-Induced TNFα and NO Expression
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- Honokiol inhibits LPS-induced maturation and inflammatory response of human monocyte-derived dendritic cells
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- Anti-Inflammatory Effects of the Neurotransmitter Agonist Honokiol in a Mouse Model of Allergic Asthma
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- Honokiol Inhibits the Progression of Collagen-Induced Arthritis by Reducing Levels of Pro-inflammatory Cytokines and Matrix Metalloproteinases and Blocking Oxidative Tissue Damage
- (2010) Ki Rim Kim et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- Combined administration of the mixture of honokiol and magnolol and ginger oil evokes antidepressant-like synergism in rats
- (2009) Li-Qin Qiang et al. ARCHIVES OF PHARMACAL RESEARCH
- Oxidative Stress and Neurodegenerative Diseases: A Review of Upstream and Downstream Antioxidant Therapeutic Options
- (2009) Bayani Uttara et al. Current Neuropharmacology
- Honokiol protects rats against eccentric exercise-induced skeletal muscle damage by inhibiting NF-κB induced oxidative stress and inflammation
- (2009) Jasson Chiang et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Honokiol reverses alcoholic fatty liver by inhibiting the maturation of sterol regulatory element binding protein-1c and the expression of its downstream lipogenesis genes
- (2009) Hu-Quan Yin et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Inhibition of NADPH oxidase-related oxidative stress-triggered signaling by honokiol suppresses high glucose-induced human endothelial cell apoptosis
- (2008) Meei Ling Sheu et al. FREE RADICAL BIOLOGY AND MEDICINE
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