The folding space of protein β2-microglobulin is modulated by a single disulfide bridge

The role of the IT-state in D76N β2-microglobulin amyloid assembly: a crucial intermediate or an innocuous bystander?

(2020) Hugh I Smith et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Early Phase of β2-Microglobulin Aggregation: Perspectives From Molecular Simulations

(2020) Rui J. S. Loureiro et al.   Frontiers in Molecular Biosciences

Visualizing and trapping transient oligomers in amyloid assembly pathways

(2020) Emma E. Cawood et al.   BIOPHYSICAL CHEMISTRY

The Early Phase of β2m Aggregation: An Integrative Computational Study Framed on the D76N Mutant and the ΔN6 Variant

(2019) Rui J. S. Loureiro et al.   Biomolecules

Successes and challenges in simulating the folding of large proteins

(2019) Anne Gershenson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity

(2018) Tanguy Le Marchand et al.   Nature Communications

A tale of two tails: The importance of unstructured termini in the aggregation pathway of β2-microglobulin

(2017) Rui J. S. Loureiro et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Coarse-Grained Protein Models and Their Applications

(2016) Sebastian Kmiecik et al.   CHEMICAL REVIEWS

Systemic Amyloidosis: Lessons from β2-Microglobulin

(2015) Monica Stoppini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein folding guides disulfide bond formation

(2015) Meng Qin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Simulated Intermediate State for Folding and Aggregation Provides Insights into ΔN6 β2-Microglobulin Amyloidogenic Behavior

(2014) Sílvia G. Estácio et al.   PLoS Computational Biology

Assessing the Effect of Loop Mutations in the Folding Space of β2-Microglobulin with Molecular Dynamics Simulations

(2013) Sílvia Estácio et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Structure, Folding Dynamics, and Amyloidogenesis of D76N β2-Microglobulin

(2013) P. Patrizia Mangione et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Robustness of atomistic Gō models in predicting native-like folding intermediates

(2012) S. G. Estácio et al.   JOURNAL OF CHEMICAL PHYSICS

Identification of a Conserved Aggregation-Prone Intermediate State in the Folding Pathways of Spc-SH3 Amyloidogenic Variants

(2012) H. Krobath et al.   JOURNAL OF MOLECULAR BIOLOGY

Discrete Molecular Dynamics: An Efficient And Versatile Simulation Method For Fine Protein Characterization

(2012) David Shirvanyants et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Hereditary Systemic Amyloidosis Due to Asp76Asn Variant β2-Microglobulin

(2012) Sophie Valleix et al.   NEW ENGLAND JOURNAL OF MEDICINE

Understanding the complex mechanisms of β2-microglobulin amyloid assembly

(2011) Timo Eichner et al.   FEBS Journal

Conformational Conversion during Amyloid Formation at Atomic Resolution

(2011) Timo Eichner et al.   MOLECULAR CELL

A Generic Mechanism of β2-Microglobulin Amyloid Assembly at Neutral pH Involving a Specific Proline Switch

(2009) Timo Eichner et al.   JOURNAL OF MOLECULAR BIOLOGY

Simulations of the protein folding process using topology-based models depend on the experimental structure

(2008) Lidia Prieto et al.   JOURNAL OF CHEMICAL PHYSICS

Topology-based models and NMR structures in protein folding simulations

(2008) M. Fernanda Rey-Stolle et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Thiol Compounds Inhibit the Formation of Amyloid Fibrils by β2-Microglobulin at Neutral pH

(2007) Kaori Yamamoto et al.   JOURNAL OF MOLECULAR BIOLOGY