Naringin and naringenin as anticancer agents and adjuvants in cancer combination therapy: Efficacy and molecular mechanisms of action, a comprehensive narrative review
出版年份 2020 全文链接
标题
Naringin and naringenin as anticancer agents and adjuvants in cancer combination therapy: Efficacy and molecular mechanisms of action, a comprehensive narrative review
作者
关键词
Cancer, Citrus, Flavonoid, Naringin, Naringenin, Signal pathways
出版物
PHARMACOLOGICAL RESEARCH
Volume 171, Issue -, Pages 105264
出版商
Elsevier BV
发表日期
2020-11-07
DOI
10.1016/j.phrs.2020.105264
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Alleviation of Multidrug Resistance by Flavonoid and Non-Flavonoid Compounds in Breast, Lung, Colorectal and Prostate Cancer
- (2020) Teodora Costea et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Curcumin Delivery Mediated by Bio-Based Nanoparticles: A Review
- (2020) Mahshid Moballegh Nasery et al. MOLECULES
- Toxicological evaluation of naringin: Acute, subchronic, and chronic toxicity in Beagle dogs
- (2020) Peibo Li et al. REGULATORY TOXICOLOGY AND PHARMACOLOGY
- A Review of Resveratrol as a Potent Chemoprotective and Synergistic Agent in Cancer Chemotherapy
- (2019) Qicai Xiao et al. Frontiers in Pharmacology
- Pharmacokinetics, Tissue Distribution, Metabolism, and Excretion of Naringin in Aged Rats
- (2019) Xuan Zeng et al. Frontiers in Pharmacology
- Naringenin Cocrystals Prepared by Solution Crystallization Method for Improving Bioavailability and Anti-hyperlipidemia Effects
- (2019) Wenxia Cui et al. AAPS PHARMSCITECH
- Naringenin-loaded nano-structured lipid carrier fortifies oxaliplatin-dependent apoptosis in HT-29 cell line
- (2019) Sina Raeisi et al. PROCESS BIOCHEMISTRY
- Potential anticancer applications of the novel naringin-based ruthenium (II) complex
- (2019) John Phillip Garcia et al. 3 Biotech
- Harmful (cyanogenic glycoside) and beneficial (phenolic) compounds in different Sambucus species
- (2019) Mateja Senica* et al. Journal of Berry Research
- Reversal of Multidrug Resistance in Cancer by Multi-Functional Flavonoids
- (2019) Qingmei Ye et al. Frontiers in Oncology
- Safety and pharmacokinetics of naringenin: A randomized, controlled, single‐ascending‐dose clinical trial
- (2019) Candida J. Rebello et al. DIABETES OBESITY & METABOLISM
- 6-C-(E-Phenylethenyl)Naringenin Attenuates the Stemness of Hepatocellular Carcinoma Cells by Suppressing Wnt/β-Catenin Signaling
- (2019) Qingzheng Kang et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Tissue distribution of naringin and derived metabolites in rats after a single oral administration
- (2019) Xuan Zeng et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Naringin suppresses the growth and motility of hypertrophic scar fibroblasts by inhibiting the kinase activity of Akt
- (2018) Yingli Song et al. BIOMEDICINE & PHARMACOTHERAPY
- Targeting the Wnt/beta-catenin pathway in cancer: Update on effectors and inhibitors
- (2018) Nithya Krishnamurthy et al. CANCER TREATMENT REVIEWS
- Effect of dietary fiber (inulin) addition on phenolics and in vitro bioaccessibility of tomato sauce
- (2018) Merve Tomas et al. FOOD RESEARCH INTERNATIONAL
- Overexpression of the Anthocyanidin Synthase Gene in Strawberry Enhances Antioxidant Capacity and Cytotoxic Effects on Human Hepatic Cancer Cells
- (2018) Francesca Giampieri et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Combination of Asiatic Acid and Naringenin Modulates NK Cell Anti-cancer Immunity by Rebalancing Smad3/Smad7 Signaling
- (2018) Guang-Yu Lian et al. MOLECULAR THERAPY
- UFLC-Q-TOF-MS/MS-Based Screening and Identification of Flavonoids and Derived Metabolites in Human Urine after Oral Administration of Exocarpium Citri Grandis Extract
- (2018) Xuan Zeng et al. MOLECULES
- Targeting activator protein 1 signaling pathway by bioactive natural agents: Possible therapeutic strategy for cancer prevention and intervention
- (2018) Devesh Tewari et al. PHARMACOLOGICAL RESEARCH
- An immunological perspective for preventing cancer with berries
- (2018) Pan Pan et al. Journal of Berry Research
- Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2018) Freddie Bray et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Manuka honey synergistically enhances the chemopreventive effect of 5-fluorouracil on human colon cancer cells by inducing oxidative stress and apoptosis, altering metabolic phenotypes and suppressing metastasis ability
- (2018) Sadia Afrin et al. FREE RADICAL BIOLOGY AND MEDICINE
- Combinatorial anti-proliferative effects of tamoxifen and naringenin: The role of four estrogen receptor subtypes
- (2018) Zhixiang Xu et al. TOXICOLOGY
- Design and development of Nrf2 modulators for cancer chemoprevention and therapy: a review
- (2018) Matej Sova et al. Drug Design Development and Therapy
- Naringenin Attenuated Prostate Cancer Invasion via Reversal of Epithelial–to–Mesenchymal Transition and Inhibited uPA Activity
- (2018) KUEI-YANG HAN et al. ANTICANCER RESEARCH
- Design and synthesis of mixed micellar system for enhanced anticancer efficacy of Paclitaxel through its co-delivery with Naringin
- (2018) Tooba Jabri et al. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
- Naringenin inhibited migration and invasion of glioblastoma cells through multiple mechanisms
- (2018) Yen-Yu Chen et al. ENVIRONMENTAL TOXICOLOGY
- Cyclooxygenase-2 in cancer: A review
- (2018) Nasser Hashemi Goradel et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Pharmacokinetic, pharmacodynamic and formulations aspects of Naringenin: An update
- (2018) Ruthvika Joshi et al. LIFE SCIENCES
- Combined administration of naringenin and hesperetin with optimal ratio maximizes the anti-cancer effect in human pancreatic cancer via down regulation of FAK and p38 signaling pathway
- (2018) Jungwhoi Lee et al. PHYTOMEDICINE
- Naringenin causes ASK1-induced apoptosis via reactive oxygen species in human pancreatic cancer cells
- (2017) Hyun Jin Park et al. FOOD AND CHEMICAL TOXICOLOGY
- Naringenin-Induced Apoptotic Cell Death in Prostate Cancer Cells Is Mediated via the PI3K/AKT and MAPK Signaling Pathways
- (2017) Whasun Lim et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Urinary metabolite profiling of flavonoids in Chinese volunteers after consumption of orange juice by UFLC-Q-TOF-MS/MS
- (2017) Xuan Zeng et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Characterisation of the antiproliferative constituents and activity of Ficus exasperata (Vahl) on ovarian cancer cells –a preliminary investigation
- (2017) Enitome E. Bafor et al. NATURAL PRODUCT RESEARCH
- The Nrf2-ARE signaling pathway: An update on its regulation and possible role in cancer prevention and treatment
- (2017) Violetta Krajka-Kuźniak et al. Pharmacological Reports
- Naringenin suppresses growth of human placental choriocarcinoma via reactive oxygen species-mediated P38 and JNK MAPK pathways
- (2017) Sunwoo Park et al. PHYTOMEDICINE
- Apigenin potentiates the antitumor activity of 5-FU on solid Ehrlich carcinoma: Crosstalk between apoptotic and JNK-mediated autophagic cell death platforms
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- Enantioselective Modulatory Effects of Naringenin Enantiomers on the Expression Levels of miR‐17‐3p Involved in Endogenous Antioxidant Defenses
- (2017) Valeria Curti et al. Nutrients
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- (2017) Irene Pafumi et al. Scientific Reports
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- (2016) Yuanwen Wang et al. AAPS PHARMSCITECH
- Nrf2 transcriptional derepression from Keap1 by dietary polyphenols
- (2016) Henry K. Bayele et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Flavanone-rich citrus beverages counteract the transient decline in postprandial endothelial function in humans: a randomised, controlled, double-masked, cross-over intervention study
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- (2016) Sonia Aroui et al. CHEMICO-BIOLOGICAL INTERACTIONS
- An Updated Review of Natural Products Intended to Prevent or Treat Oral Mucositis in Patients Undergoing Radio-Chemotherapy
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- JAK-STAT signaling in cancer: From cytokines to non-coding genome
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- 6-C-(E-phenylethenyl)naringenin induces cell growth inhibition and cytoprotective autophagy in colon cancer cells
- (2016) Yueliang Zhao et al. EUROPEAN JOURNAL OF CANCER
- Identification of Naringin Metabolites in Human Urine and Feces
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- NEU3 inhibitory effect of naringin suppresses cancer cell growth by attenuation of EGFR signaling through GM3 ganglioside accumulation
- (2016) Ayana Yoshinaga et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Naringin suppresses the development of glioblastoma by inhibiting FAK activity
- (2016) Jinjiang Li et al. JOURNAL OF DRUG TARGETING
- STAT5 in Cancer and Immunity
- (2016) Aradhana Rani et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- Bioavailability of tomato polyphenols is enhanced by processing and fat addition: Evidence from a randomized feeding trial
- (2016) Miriam Martínez-Huélamo et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Wnt signaling in cancer
- (2016) T Zhan et al. ONCOGENE
- Naringenin inhibits proliferation, migration, and invasion as well as induces apoptosis of gastric cancer SGC7901 cell line by downregulation of AKT pathway
- (2016) Lei Bao et al. TUMOR BIOLOGY
- Naringenin inhibits migration of lung cancer cells via the inhibition of matrix metalloproteinases-2 and −9
- (2016) Huai-Lu Chang et al. Experimental and Therapeutic Medicine
- Dietary Natural Products for Prevention and Treatment of Liver Cancer
- (2016) Yue Zhou et al. Nutrients
- Chemopreventive Agents and Inhibitors of Cancer Hallmarks: May Citrus Offer New Perspectives?
- (2016) Santa Cirmi et al. Nutrients
- Bergamot Reduces Plasma Lipids, Atherogenic Small Dense LDL, and Subclinical Atherosclerosis in Subjects with Moderate Hypercholesterolemia: A 6 Months Prospective Study
- (2016) Peter P. Toth et al. Frontiers in Pharmacology
- Mutational Profiles Reveal an Aberrant TGF-β-CEA Regulated Pathway in Colon Adenomas
- (2016) Jian Chen et al. PLoS One
- Flavanones protect from arterial stiffness in postmenopausal women consuming grapefruit juice for 6 mo: a randomized, controlled, crossover trial
- (2015) Véronique Habauzit et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Anti-Proliferative Effect of Naringenin through p38-Dependent Downregulation of Cyclin D1 in Human Colorectal Cancer Cells
- (2015) Hun Min Song et al. Biomolecules & Therapeutics
- High gastrointestinal permeability and local metabolism of naringenin: influence of antibiotic treatment on absorption and metabolism
- (2015) Naiara Orrego-Lagarón et al. BRITISH JOURNAL OF NUTRITION
- Global Cancer Incidence and Mortality Rates and Trends--An Update
- (2015) L. A. Torre et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Notch signaling: An emerging therapeutic target for cancer treatment
- (2015) Xun Yuan et al. CANCER LETTERS
- Naringenin suppresses TPA-induced tumor invasion by suppressing multiple signal transduction pathways in human hepatocellular carcinoma cells
- (2015) Hung-Rong Yen et al. CHEMICO-BIOLOGICAL INTERACTIONS
- 5-Fluorouracil combined with apigenin enhances anticancer activity through mitochondrial membrane potential (ΔΨm)-mediated apoptosis in hepatocellular carcinoma
- (2015) Xiao-Yun Hu et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- Marked antioxidant effect of orange juice intake and its phytomicronutrients in a preliminary randomized cross-over trial on mild hypercholesterolemic men
- (2015) Joël Constans et al. CLINICAL NUTRITION
- The Role of Hesperidin in Cell Signal Transduction Pathway for the Prevention or Treatment of Cancer
- (2015) A. Ahmadi et al. CURRENT MEDICINAL CHEMISTRY
- High-dose short-term administration of naringin did not alter talinolol pharmacokinetics in humans
- (2015) M.A. Nguyen et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Significance of Antioxidant Potential of Plants and its Relevance to Therapeutic Applications
- (2015) Deepak M. Kasote et al. International Journal of Biological Sciences
- Naringin induces autophagy-mediated growth inhibition by downregulating the PI3K/Akt/mTOR cascade via activation of MAPK pathways in AGS cancer cells
- (2015) SUCHISMITA RAHA et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Naringin, a natural dietary compound, prevents intestinal tumorigenesis in Apc Min/+ mouse model
- (2015) Yu-Sheng Zhang et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Oxidative stress and cancer; the role of hesperidin, a citrus natural bioflavonoid, as a cancer chemoprotective agent
- (2015) Amirhossein Ahmadi et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- Naringin suppresses the metabolism of A375 cells by inhibiting the phosphorylation of c-Src
- (2015) Bingyu Guo et al. TUMOR BIOLOGY
- Naringin inhibits the invasion and migration of human glioblastoma cell via downregulation of MMP-2 and MMP-9 expression and inactivation of p38 signaling pathway
- (2015) Sonia Aroui et al. TUMOR BIOLOGY
- Impact of food matrix and processing on the in vitro bioaccessibility of vitamin C, phenolic compounds, and hydrophilic antioxidant activity from fruit juice-based beverages
- (2015) María Janeth Rodríguez-Roque et al. Journal of Functional Foods
- Naringenin suppresses K562 human leukemia cell proliferation and ameliorates Adriamycin-induced oxidative damage in polymorphonuclear leukocytes
- (2015) RUI-FANG LI et al. Experimental and Therapeutic Medicine
- Enhanced anticancer effect of ABT-737 in combination with naringenin on gastric cancer cells
- (2015) HAIYANG ZHANG et al. Experimental and Therapeutic Medicine
- Enhanced action of apigenin and naringenin combination on estrogen receptor activation in non-malignant colonocytes: implications on sorghum-derived phytoestrogens
- (2015) Liyi Yang et al. Food & Function
- JAK Kinase Inhibition Abrogates STAT3 Activation and Head and Neck Squamous Cell Carcinoma Tumor Growth
- (2015) Malabika Sen et al. NEOPLASIA
- Modulation of Anticancer Drug-Induced P-Glycoprotein Expression by Naringin
- (2015) Mamdouh M. Ali et al. ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES
- Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-κB regulated gene products in multiple myeloma xenograft mouse model
- (2015) Kodappully Sivaraman Siveen et al. Oncotarget
- γ-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model
- (2015) Kodappully Sivaraman Siveen et al. Oncotarget
- Notch signaling: switching an oncogene to a tumor suppressor
- (2014) C. Lobry et al. BLOOD
- Cancer treatment and survivorship statistics, 2014
- (2014) Carol E. DeSantis et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Dietary phytochemicals alter epigenetic events and signaling pathways for inhibition of metastasis cascade
- (2014) B. N. Singh et al. CANCER AND METASTASIS REVIEWS
- Novel oxime based flavanone, naringin-oxime: Synthesis, characterization and screening for antioxidant activity
- (2014) Mustafa Özyürek et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Molecular Pathways: Translational and Therapeutic Implications of the Notch Signaling Pathway in Cancer
- (2014) R. A. Previs et al. CLINICAL CANCER RESEARCH
- Safety evaluation of naringenin upon experimental exposure on rat gastrointestinal epithelium for novel optimal drug delivery
- (2014) Gurunath Surampalli et al. DRUG DELIVERY
- Human intestinal microbial metabolism of naringin
- (2014) Wei Zou et al. EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS
- A naringenin–tamoxifen combination impairs cell proliferation and survival of MCF-7 breast cancer cells
- (2014) Talia Hatkevich et al. EXPERIMENTAL CELL RESEARCH
- Naringin suppress chondrosarcoma migration through inhibition vascular adhesion molecule-1 expression by modulating miR-126
- (2014) Tzu-Wei Tan et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012
- (2014) Jacques Ferlay et al. INTERNATIONAL JOURNAL OF CANCER
- Mitigating the Effects of Xuebijing Injection on Hematopoietic Cell Injury Induced by Total Body Irradiation with γ rays by Decreasing Reactive Oxygen Species Levels
- (2014) Deguan Li et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Naringin inhibits growth and induces apoptosis by a mechanism dependent on reduced activation of NF-κB/COX-2-caspase-1 pathway in HeLa cervical cancer cells
- (2014) LAN ZENG et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Naringenin inhibits migration of bladder cancer cells through downregulation of AKT and MMP-2
- (2014) ALEX CHIEN HWA LIAO et al. Molecular Medicine Reports
- Genoprotective effects ofOriganum vulgareethanolic extract against cyclophosphamide-induced genotoxicity in mouse bone marrow cells
- (2014) Emran Habibi et al. PHARMACEUTICAL BIOLOGY
- Preclinical Evidence for the Pharmacological Actions of Naringin: A Review
- (2014) Saurabh Bharti et al. PLANTA MEDICA
- Induction of Apoptosis and Antiproliferative Activity of Naringenin in Human Epidermoid Carcinoma Cell through ROS Generation and Cell Cycle Arrest
- (2014) Md Sultan Ahamad et al. PLoS One
- Focal Adhesion Kinase Functions as an Akt Downstream Target in Migration of Colorectal Cancer Cells
- (2014) Jolana Turečková et al. Translational Oncology
- Effect of Citrus Flavonoids, Naringin and Naringenin, on Metabolic Syndrome and Their Mechanisms of Action
- (2014) M. Ashraful Alam et al. Advances in Nutrition
- Preparation of Naringenin/β-Cyclodextrin Complex and Its More Potent Alleviative Effect on Choroidal Neovascularization in Rats
- (2014) Xin-rong Xu et al. Biomed Research International
- STAT3 in Cancer—Friend or Foe?
- (2014) Hai-Feng Zhang et al. Cancers
- Targeting PI3K/Akt/mTOR Signaling in Cancer
- (2014) Camillo Porta et al. Frontiers in Oncology
- An Eco-Friendly Enantioselective Access to (R)-Naringenin as Inhibitor of Proinflammatory Cytokine Release
- (2013) Raffaella Gaggeri et al. CHEMISTRY & BIODIVERSITY
- Acute and 13weeks subchronic toxicological evaluation of naringin in Sprague-Dawley rats
- (2013) Peibo Li et al. FOOD AND CHEMICAL TOXICOLOGY
- Effects of naringenin and its phase II metabolites onin vitrohuman macrophage gene expression
- (2013) Margherita Dall’Asta et al. INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION
- Role of Notch signalling pathway in cancer and its association with DNA methylation
- (2013) MADHURI G. S. AITHAL et al. JOURNAL OF GENETICS
- Naringenin (Citrus Flavonone) Induces Growth Inhibition, Cell Cycle Arrest and Apoptosis in Human Hepatocellular Carcinoma Cells
- (2013) Duraikannu Arul et al. PATHOLOGY & ONCOLOGY RESEARCH
- Clinical Study to Assess the Efficacy and Safety of a Citrus Polyphenolic Extract of Red Orange, Grapefruit, and Orange (Sinetrol-XPur) on Weight Management and Metabolic Parameters in Healthy Overweight Individuals
- (2013) Constantin Dallas et al. PHYTOTHERAPY RESEARCH
- Targeting the PI3-Kinase/Akt/mTOR Signaling Pathway
- (2013) Burhan Hassan et al. Surgical Oncology Clinics of North America
- The Mitigating Effect ofCitrullus colocynthis(L.) Fruit Extract against Genotoxicity Induced by Cyclophosphamide in Mice Bone Marrow Cells
- (2013) Mohammad Shokrzadeh et al. TheScientificWorldJOURNAL
- Chemistry and Biological Activities of Flavonoids: An Overview
- (2013) Shashank Kumar et al. TheScientificWorldJOURNAL
- Naringin inhibits growth potential of human triple-negative breast cancer cells by targeting β-catenin signaling pathway
- (2013) Hongzhong Li et al. TOXICOLOGY LETTERS
- Caspase Functions in Cell Death and Disease
- (2013) D. R. McIlwain et al. Cold Spring Harbor Perspectives in Biology
- Cellular Mechanisms Controlling Caspase Activation and Function
- (2013) A. B. Parrish et al. Cold Spring Harbor Perspectives in Biology
- Tissue Distribution Study of Naringin in Rats by Liquid Chromatography-Tandem Mass Spectrometry
- (2012) W. Zou et al. ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH
- Key cell signaling pathways modulated by zerumbone: Role in the prevention and treatment of cancer
- (2012) Remya Prasannan et al. BIOCHEMICAL PHARMACOLOGY
- Metabolism and excretion studies of oral administered naringin, a putative antitussive, in rats and dogs
- (2012) Menghua Liu et al. BIOPHARMACEUTICS & DRUG DISPOSITION
- Effects of p-Synephrine alone and in Combination with Selected Bioflavonoids on Resting Metabolism, Blood Pressure, Heart Rate and Self-Reported Mood Changes
- (2012) Sidney J. Stohs et al. International Journal of Medical Sciences
- Targeting the Interleukin-6/Jak/Stat Pathway in Human Malignancies
- (2012) Pasquale Sansone et al. JOURNAL OF CLINICAL ONCOLOGY
- Naringenin Decreases Invasiveness and Metastasis by Inhibiting TGF-β-Induced Epithelial to Mesenchymal Transition in Pancreatic Cancer Cells
- (2012) Changjie Lou et al. PLoS One
- PI3K-PKB/Akt Pathway
- (2012) B. A. Hemmings et al. Cold Spring Harbor Perspectives in Biology
- Enantiomers of naringenin as pleiotropic, stereoselective inhibitors of cytochrome P450 isoforms
- (2011) Wenjie Jessie Lu et al. CHIRALITY
- Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases
- (2011) M. Cargnello et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
- (2011) Gina M. DeNicola et al. NATURE
- Polyphenols and Human Health: Prevention of Disease and Mechanisms of Action
- (2011) David Vauzour et al. Nutrients
- Naringenin reduces lung metastasis in a breast cancer resection model
- (2011) Lei Qin et al. Protein & Cell
- Synergic effect of α-tocopherol and naringenin in transglutaminase-induced differentiation of human prostate cancer cells
- (2010) Piera Torricelli et al. AMINO ACIDS
- Fruit juice inhibition of uptake transport: a new type of food-drug interaction
- (2010) David G. Bailey BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Carcinoembryonic Antigen Interacts with TGF- Receptor and Inhibits TGF- Signaling in Colorectal Cancers
- (2010) Y. Li et al. CANCER RESEARCH
- How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer?
- (2010) Yohannes Mebratu et al. CELL CYCLE
- Oxidative stress, inflammation, and cancer: How are they linked?
- (2010) Simone Reuter et al. FREE RADICAL BIOLOGY AND MEDICINE
- c-Jun Induces Mammary Epithelial Cellular Invasion and Breast Cancer Stem Cell Expansion
- (2010) Xuanmao Jiao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Citrus Flavonoids Hesperidin and Naringin Do Not Affect Serum Cholesterol in Moderately Hypercholesterolemic Men and Women
- (2010) Isabelle Demonty et al. JOURNAL OF NUTRITION
- The dynamic roles of TGF-β in cancer
- (2010) Erik Meulmeester et al. JOURNAL OF PATHOLOGY
- Signal transduction therapy of cancer
- (2010) Alexander Levitzki et al. MOLECULAR ASPECTS OF MEDICINE
- Potent and Selective Inhibition of Polycythemia by the Quinoxaline JAK2 Inhibitor NVP-BSK805
- (2010) F. Baffert et al. MOLECULAR CANCER THERAPEUTICS
- Safety and Efficacy of INCB018424, a JAK1 and JAK2 Inhibitor, in Myelofibrosis
- (2010) Srdan Verstovsek et al. NEW ENGLAND JOURNAL OF MEDICINE
- Wnt signal transduction pathways
- (2010) Yuko Komiya et al. Organogenesis
- Naringenin: A Potential Immunomodulator for Inhibiting Lung Fibrosis and Metastasis
- (2009) G. Du et al. CANCER RESEARCH
- Naringin inhibits matrix metalloproteinase-9 expression and AKT phosphorylation in tumor necrosis factor-α-induced vascular smooth muscle cells
- (2009) Eo-Jin Lee et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Targeting the phosphoinositide 3-kinase pathway in cancer
- (2009) Pixu Liu et al. NATURE REVIEWS DRUG DISCOVERY
- Cranberry proanthocyanidins are cytotoxic to human cancer cells and sensitize platinum-resistant ovarian cancer cells to paraplatin
- (2009) Ajay P. Singh et al. PHYTOTHERAPY RESEARCH
- Bcl-2 inhibitors: small molecules with a big impact on cancer therapy
- (2008) M Vogler et al. CELL DEATH AND DIFFERENTIATION
- Signaling cross-talk between TGF-β/BMP and other pathways
- (2008) Xing Guo et al. CELL RESEARCH
- Natural products and colon cancer: current status and future prospects
- (2008) Subapriya Rajamanickam et al. DRUG DEVELOPMENT RESEARCH
- Protein tyrosine phosphatases in the JAK/STAT pathway
- (2008) Dan Xu Frontiers in Bioscience-Landmark
- Src family kinases promote AML cell survival through activation of signal transducers and activators of transcription (STAT)
- (2008) Yukiyasu Ozawa et al. LEUKEMIA RESEARCH
- Naringenin Enhances the Anti-Tumor Effect of Doxorubicin Through Selectively Inhibiting the Activity of Multidrug Resistance-Associated Proteins but not P-glycoprotein
- (2008) Fa Yun Zhang et al. PHARMACEUTICAL RESEARCH
- Pharmacokinetics of selected chiral flavonoids: hesperetin, naringenin and eriodictyol in rats and their content in fruit juices
- (2007) Jaime A. Yáñez et al. BIOPHARMACEUTICS & DRUG DISPOSITION
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