Discovery of bicyclic inhibitors against menaquinone biosynthesis

MRSA Infections: From Classical Treatment to Suicide Drugs

(2014) Julia Drebes et al.   CURRENT MEDICINAL CHEMISTRY

Structure of a Membrane-Embedded Prenyltransferase Homologous to UBIAD1

(2014) Hua Huang et al.   PLOS BIOLOGY

Synthesis of azide derivative and discovery of glyoxalase pathway inhibitor against pathogenic bacteria

(2013) Benson Edagwa et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Identification of a Hotdog Fold Thioesterase Involved in the Biosynthesis of Menaquinone in Escherichia coli

(2013) M. Chen et al.   JOURNAL OF BACTERIOLOGY

Cytotoxicity and modes of action of four naturally occuring benzophenones: 2,2′,5,6′-Tetrahydroxybenzophenone, guttiferone E, isogarcinol and isoxanthochymol

(2013) Victor Kuete et al.   PHYTOMEDICINE

Discovery of Selective Menaquinone Biosynthesis Inhibitors against Mycobacterium tuberculosis

(2012) Joy Debnath et al.   JOURNAL OF MEDICINAL CHEMISTRY

Stable Analogues of OSB-AMP: Potent Inhibitors of MenE, the o-Succinylbenzoate-CoA Synthetase from Bacterial Menaquinone Biosynthesis

(2011) Xuequan Lu et al.   CHEMBIOCHEM

CoA Adducts of 4-Oxo-4-phenylbut-2-enoates: Inhibitors of MenB from the M. tuberculosis Menaquinone Biosynthesis Pathway

(2011) Xiaokai Li et al.   ACS Medicinal Chemistry Letters

Menaquinone synthesis is critical for maintaining mycobacterial viability during exponential growth and recovery from non-replicating persistence

(2009) Rakesh K. Dhiman et al.   MOLECULAR MICROBIOLOGY

An Alternative Menaquinone Biosynthetic Pathway Operating in Microorganisms

(2008) T. Hiratsuka et al.   SCIENCE