Dexamethasone suppresses immune evasion by inducing GR/STAT3 mediated downregulation of PD-L1 and IDO1 pathways
出版年份 2021 全文链接
标题
Dexamethasone suppresses immune evasion by inducing GR/STAT3 mediated downregulation of PD-L1 and IDO1 pathways
作者
关键词
-
出版物
ONCOGENE
Volume 40, Issue 31, Pages 5002-5012
出版商
Springer Science and Business Media LLC
发表日期
2021-06-27
DOI
10.1038/s41388-021-01897-0
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Response to: ‘Correspondence on ‘Historically controlled comparison of glucocorticoids with or without tocilizumab versus supportive care only in patients with COVID-19-associated cytokine storm syndrome: results of the CHIC study’’ by Charles
- (2021) Josef S Smolen ANNALS OF THE RHEUMATIC DISEASES
- Correspondence on ‘Historically controlled comparison of glucocorticoids with or without tocilizumab versus supportive care only in patients with COVID-19-associated cytokine storm syndrome: results of the CHIC study’
- (2021) Maria De Santis et al. ANNALS OF THE RHEUMATIC DISEASES
- Response to: ‘Correspondence on ‘Historically controlled comparison of glucocorticoids with or without tocilizumab versus supportive care only in patients with COVID-19-associated cytokine storm syndrome: results of the CHIC study’’ by De Santis et al
- (2021) Sofia Ramiro et al. ANNALS OF THE RHEUMATIC DISEASES
- Response to: ’Correspondence on ‘Historically controlled comparison of glucocorticoids with or without tocilizumab versus supportive care only in patients with COVID-19-associated cytokine storm syndrome: results of the CHIC study’’ by Charles
- (2021) Sofia Ramiro et al. ANNALS OF THE RHEUMATIC DISEASES
- Correspondence on ‘Historically controlled comparison of glucocorticoids with or without tocilizumab versus supportive care only in patients with COVID-19-associated cytokine storm syndrome: results of the CHIC study’
- (2021) Pierre Charles ANNALS OF THE RHEUMATIC DISEASES
- Efficacy of early anti-inflammatory treatment with high doses of intravenous anakinra with or without glucocorticoids in patients with severe COVID-19 pneumonia
- (2021) Emanuele Pontali et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Historically controlled comparison of glucocorticoids with or without tocilizumab versus supportive care only in patients with COVID-19-associated cytokine storm syndrome: results of the CHIC study
- (2020) Sofia Ramiro et al. ANNALS OF THE RHEUMATIC DISEASES
- Effect of Systemic Glucocorticoids on Mortality or Mechanical Ventilation in Patients With COVID-19
- (2020) Marla J Keller et al. Journal of Hospital Medicine
- Inpatient use of glucocorticoids may mediate the detrimental effect of new-onset hyperglycemia on COVID-19 severity
- (2020) Gerui Li DIABETES RESEARCH AND CLINICAL PRACTICE
- Screening responsive or resistant biomarkers of immune checkpoint inhibitors based on online databases
- (2019) Zhen Xiang et al. Frontiers of Medicine
- An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics
- (2018) Jianfang Liu et al. CELL
- Computational drug repositioning for rare diseases in the era of precision medicine
- (2018) Brian Delavan et al. DRUG DISCOVERY TODAY
- Regulation and Function of the PD-L1 Checkpoint
- (2018) Chong Sun et al. IMMUNITY
- Divergent Routes toward Wnt and R-spondin Niche Independency during Human Gastric Carcinogenesis
- (2018) Kosaku Nanki et al. CELL
- Impact of Baseline Steroids on Efficacy of Programmed Cell Death-1 and Programmed Death-Ligand 1 Blockade in Patients With Non–Small-Cell Lung Cancer
- (2018) Kathryn C. Arbour et al. JOURNAL OF CLINICAL ONCOLOGY
- Inhibiting IDO pathways to treat cancer: lessons from the ECHO-301 trial and beyond
- (2018) Alexander J. Muller et al. Seminars in Immunopathology
- Cross-Database Analysis Reveals Sensitive Biomarkers for Combined Therapy for ERBB2+ Gastric Cancer
- (2018) Zhen Xiang et al. Frontiers in Pharmacology
- Organoid Modeling of the Tumor Immune Microenvironment
- (2018) James T. Neal et al. CELL
- Fibrinogen-like Protein 1 Is a Major Immune Inhibitory Ligand of LAG-3
- (2018) Jun Wang et al. CELL
- Updates in the Clinical Development of Epacadostat and Other Indoleamine 2,3-Dioxygenase 1 Inhibitors (IDO1) for Human Cancers
- (2018) Takefumi Komiya et al. Frontiers in Oncology
- A positive crosstalk between CXCR4 and CXCR2 promotes gastric cancer metastasis
- (2017) Z Xiang et al. ONCOGENE
- PSMA-targeted polyinosine/polycytosine vector induces prostate tumor regression and invokes an antitumor immune response in mice
- (2017) Yael Langut et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tumour and host cell PD-L1 is required to mediate suppression of anti-tumour immunity in mice
- (2017) Janet Lau et al. Nature Communications
- Epacadostat Shows Value in Two SCCHN Trials
- (2017) Cancer Discovery
- Resistance Mechanisms to Immune-Checkpoint Blockade in Cancer: Tumor-Intrinsic and -Extrinsic Factors
- (2016) Jonathan M. Pitt et al. IMMUNITY
- Monocyte-macrophage differentiation of acute myeloid leukemia cell lines by small molecules identified through interrogation of the Connectivity Map database
- (2015) Gloria Manzotti et al. CELL CYCLE
- A Randomised Phase 2 Trial of Dexamethasone Versus Prednisolone in Castration-resistant Prostate Cancer
- (2015) Ramachandran Venkitaraman et al. EUROPEAN UROLOGY
- Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma
- (2015) James Larkin et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Review: Phytochemicals Targeting JAK/STAT Signaling and IDO Expression in Cancer
- (2015) Niroshaathevi Arumuggam et al. PHYTOTHERAPY RESEARCH
- The future of immune checkpoint therapy
- (2015) P. Sharma et al. SCIENCE
- Suppression of TDO-mediated tryptophan catabolism in glioblastoma cells by a steroid-responsive FKBP52-dependent pathway
- (2014) Martina Ott et al. GLIA
- Tissue-Specific Actions of Glucocorticoids on Apoptosis: A Double-Edged Sword
- (2013) Amanda Gruver-Yates et al. Cells
- Chronic exposure to stress predisposes to higher autoimmune susceptibility in C57BL/6 mice: Glucocorticoids as a double-edged sword
- (2012) Idan Harpaz et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The Stat3/GR Interaction Code: Predictive Value of Direct/Indirect DNA Recruitment for Transcription Outcome
- (2012) David Langlais et al. MOLECULAR CELL
- The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
- (2012) Jordi Barretina et al. NATURE
- Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer
- (2012) Julie R. Brahmer et al. NEW ENGLAND JOURNAL OF MEDICINE
- The Indoleamine-2,3-Dioxygenase (IDO) Inhibitor 1-Methyl-D-tryptophan Upregulates IDO1 in Human Cancer Cells
- (2011) Christiane A. Opitz et al. PLoS One
- Dexamethasone reduces tumor recurrence and metastasis after pancreatic tumor resection in SCID mice
- (2010) Jan-Hendrik Egberts et al. CANCER BIOLOGY & THERAPY
- Cutting Edge: Negative Regulation of Dendritic Cells through Acetylation of the Nonhistone Protein STAT-3
- (2009) Yaping Sun et al. JOURNAL OF IMMUNOLOGY
- Cancer-related inflammation
- (2008) Alberto Mantovani et al. NATURE
- Oncogenic kinase NPM/ALK induces through STAT3 expression of immunosuppressive protein CD274 (PD-L1, B7-H1)
- (2008) M. Marzec et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started