High-affinity five/six-letter DNA aptamers with superior specificity enabling the detection of dengue NS1 protein variants beyond the serotype identification

Beyond small molecules: targeting G-quadruplex structures with oligonucleotides and their analogues

(2021) Enrico Cadoni et al.   NUCLEIC ACIDS RESEARCH

Serotype-specific detection of dengue viruses in a nonstructural protein 1-based enzyme-linked immunosorbent assay validated with a multi-national cohort

(2020) Irene Bosch et al.   PLoS Neglected Tropical Diseases

Recent Progress in Plasmonic Biosensing Schemes for Virus Detection

(2020) Elba Mauriz   SENSORS

Development of Dengue-type NS1 ELISA for Rapid Detection and Differentiation of Dengue Serotypes during Early Infection

(2019) Szu-Chia Lai et al.   JOURNAL OF CLINICAL MICROBIOLOGY

DNA Sequencing Method Including Unnatural Bases for DNA Aptamer Generation by Genetic Alphabet Expansion

(2019) Kiyofumi Hamashima et al.   ACS Synthetic Biology

Molecular affinity rulers: systematic evaluation of DNA aptamers for their applicabilities in ELISA

(2019) Michiko Kimoto et al.   NUCLEIC ACIDS RESEARCH

Aptamer chemistry

(2018) Pascal Röthlisberger et al.   ADVANCED DRUG DELIVERY REVIEWS

DNA aptamer generation by ExSELEX using genetic alphabet expansion with a mini-hairpin DNA stabilization method

(2018) Ichiro Hirao et al.   BIOCHIMIE

Development of Dengue Virus Serotype–Specific NS1 Capture Assays for the Rapid and Highly Sensitive Identification of the Infecting Serotype in Human Sera

(2018) Katharina Röltgen et al.   JOURNAL OF IMMUNOLOGY

Identification and characterization of nucleobase-modified aptamers by click-SELEX

(2018) Franziska Pfeiffer et al.   Nature Protocols

Creation of unnatural base pairs for genetic alphabet expansion toward synthetic xenobiology

(2018) Kiyofumi Hamashima et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Genetic Alphabet Expansion Provides Versatile Specificities and Activities of Unnatural-Base DNA Aptamers Targeting Cancer Cells

(2018) Kazunobu Futami et al.   Molecular Therapy-Nucleic Acids

Clinical and Laboratory Diagnosis of Dengue Virus Infection

(2017) David A. Muller et al.   JOURNAL OF INFECTIOUS DISEASES

Selection of 2′-Fluoro-Modified Aptamers with Optimized Properties

(2017) Deepak Thirunavukarasu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multiplex PCR method for MinION and Illumina sequencing of Zika and other virus genomes directly from clinical samples

(2017) Joshua Quick et al.   Nature Protocols

RNA–protein interactions govern antiviral specificity and encapsidation of broad spectrum anti-HIV reverse transcriptase aptamers

(2017) Margaret J. Lange et al.   NUCLEIC ACIDS RESEARCH

Selection of DNA aptamers with two modified bases

(2017) Bharat N. Gawande et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid antigen tests for dengue virus serotypes and Zika virus in patient serum

(2017) Irene Bosch et al.   Science Translational Medicine

Isolation of serotype-specific antibodies against dengue virus non-structural protein 1 using phage display and application in a multiplexed serotyping assay

(2017) Kebaneilwe Lebani et al.   PLoS One

High-Affinity DNA Aptamer Generation Targeting von Willebrand Factor A1-Domain by Genetic Alphabet Expansion for Systematic Evolution of Ligands by Exponential Enrichment Using Two Types of Libraries Composed of Five Different Bases

(2016) Ken-ichiro Matsunaga et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enhancing aptamer function and stability via in vitro selection using modified nucleic acids

(2016) Kirsten N. Meek et al.   METHODS

Aptamers as targeted therapeutics: current potential and challenges

(2016) Jiehua Zhou et al.   NATURE REVIEWS DRUG DISCOVERY

Analysis of In Vitro Aptamer Selection Parameters

(2015) Maureen McKeague et al.   JOURNAL OF MOLECULAR EVOLUTION

Evolution of Functional Six-Nucleotide DNA

(2015) Liqin Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The isolation of an RNA aptamer targeting to p53 protein with single amino acid mutation

(2015) Liang Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Architecture of high-affinity unnatural-base DNA aptamers toward pharmaceutical applications

(2015) Ken-ichiro Matsunaga et al.   Scientific Reports

Chemically Modified DNA Aptamers Bind Interleukin-6 with High Affinity and Inhibit Signaling by Blocking Its Interaction with Interleukin-6 Receptor

(2014) Shashi Gupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Assessing Positivity and Circulating Levels of NS1 in Samples from a 2012 Dengue Outbreak in Rio de Janeiro, Brazil

(2014) Diego Allonso et al.   PLoS One

Nucleic Acid Ligands With Protein-like Side Chains: Modified Aptamers and Their Use as Diagnostic and Therapeutic Agents

(2014) John C Rohloff et al.   Molecular Therapy-Nucleic Acids

The flavivirus NS1 protein: Molecular and structural biology, immunology, role in pathogenesis and application as a diagnostic biomarker

(2013) David A. Muller et al.   ANTIVIRAL RESEARCH

Generation of high-affinity DNA aptamers using an expanded genetic alphabet

(2013) Michiko Kimoto et al.   NATURE BIOTECHNOLOGY

In vitro selection with artificial expanded genetic information systems

(2013) K. Sefah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Highly specific unnatural base pair systems as a third base pair for PCR amplification

(2011) Rie Yamashige et al.   NUCLEIC ACIDS RESEARCH

Monitoring the site-specific incorporation of dual fluorophore-quencher base analogues for target DNA detection by an unnatural base pair system

(2011) Rie Yamashige et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

An unnatural base pair system for efficient PCR amplification and functionalization of DNA molecules

(2008) Michiko Kimoto et al.   NUCLEIC ACIDS RESEARCH