Donepezil Protects Against Doxorubicin-Induced Chemobrain in Rats via Attenuation of Inflammation and Oxidative Stress Without Interfering With Doxorubicin Efficacy

Reactive astrocyte nomenclature, definitions, and future directions

(2021) Carole Escartin et al.   NATURE NEUROSCIENCE

Bone marrow mesenchymal stem cells and their derived exosomes resolve doxorubicin-induced chemobrain: critical role of their miRNA cargo

(2021) Marwa O. El-Derany et al.   Stem Cell Research & Therapy

An Overview of Nicotinic Cholinergic System Signaling in Neurogenesis

(2020) Zahra Shabani et al.   ARCHIVES OF MEDICAL RESEARCH

The Role of Mitochondria in Neurodegenerative Diseases: the Lesson from Alzheimer’s Disease and Parkinson’s Disease

(2020) Giacomo Monzio Compagnoni et al.   MOLECULAR NEUROBIOLOGY

Chronic Peripheral Inflammation Causes a Region-Specific Myeloid Response in the Central Nervous System

(2020) Patrick Süß et al.   Cell Reports

Protective effects of diallyl trisulfide (DATS) against doxorubicin-induced inflammation and oxidative stress in the brain of rats

(2020) Wai-Shing Leung et al.   FREE RADICAL BIOLOGY AND MEDICINE

Donepezil provides neuroprotective effects against brain injury and Alzheimer's pathology under conditions of cardiac ischemia/reperfusion injury

(2020) Benjamin Ongnok et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Astrocytes and microglia in neurodegenerative diseases: Lessons from human in vitro models

(2020) Hannah Franklin et al.   PROGRESS IN NEUROBIOLOGY

Neuroinflammation in neurodegenerative disorders: the roles of microglia and astrocytes

(2020) Hyuk Sung Kwon et al.   Translational Neurodegeneration

Changes in health-related quality of life among gynecologic cancer survivors during the two years after initial treatment: a longitudinal analysis

(2019) Nathalie Zandbergen et al.   ACTA ONCOLOGICA

Chemotherapy accelerates age-related development of tauopathy and results in loss of synaptic integrity and cognitive impairment

(2019) Angie C.A. Chiang et al.   BRAIN BEHAVIOR AND IMMUNITY

N-acetyl cysteine, inulin and the two as a combined therapy ameliorate cognitive decline in testosterone-deprived rats

(2019) Titikorn Chunchai et al.   Aging-US

Attenuation of neuroinflammation reverses Adriamycin-induced cognitive impairments

(2019) Barrett D. Allen et al.   Acta Neuropathologica Communications

Doxorubicin and cisplatin induced cognitive impairment: The possible mechanisms and interventions

(2019) Benjamin Ongnok et al.   EXPERIMENTAL NEUROLOGY

Cancer statistics, 2018

(2018) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Decreased microglial activation through gut-brain axis by prebiotics, probiotics, or synbiotics effectively restored cognitive function in obese-insulin resistant rats

(2018) Titikorn Chunchai et al.   Journal of Neuroinflammation

Microglial Ramification, Surveillance, and Interleukin-1β Release Are Regulated by the Two-Pore Domain K + Channel THIK-1

(2018) Christian Madry et al.   NEURON

Physical exercise prevents cognitive impairment by enhancing hippocampal neuroplasticity and mitochondrial function in doxorubicin-induced chemobrain

(2018) Hye-Sang Park et al.   NEUROPHARMACOLOGY

Novel Object Recognition and Object Location Behavioral Testing in Mice on a Budget

(2018) Jiyeon K. Denninger et al.   Jove-Journal of Visualized Experiments

The triangle of death of neurons: Oxidative damage, mitochondrial dysfunction, and loss of choline-containing biomolecules in brains of mice treated with doxorubicin. Advanced insights into mechanisms of chemotherapy induced cognitive impairment (“chemobrain”) involving TNF-α

(2018) Xiaojia Ren et al.   FREE RADICAL BIOLOGY AND MEDICINE

Astaxanthin Ameliorates Doxorubicin-Induced Cognitive Impairment (Chemobrain) in Experimental Rat Model: Impact on Oxidative, Inflammatory, and Apoptotic Machineries

(2017) Sara Emad El-Agamy et al.   MOLECULAR NEUROBIOLOGY

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Mitophagy in neurodegeneration and aging

(2017) Elayne M. Fivenson et al.   NEUROCHEMISTRY INTERNATIONAL

Involvement of Astrocytes in Alzheimer’s Disease from a Neuroinflammatory and Oxidative Stress Perspective

(2017) Rodrigo E. González-Reyes et al.   Frontiers in Molecular Neuroscience

Cancer treatment and survivorship statistics, 2016

(2016) Kimberly D. Miller et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Reactive astrocytes and therapeutic potential in focal ischemic stroke

(2016) Gourav Roy Choudhury et al.   NEUROBIOLOGY OF DISEASE

PET Evidence of the Effect of Donepezil on Cognitive Performance in an Animal Model of Chemobrain

(2016) Ilhan Lim et al.   Biomed Research International

Analyzing dendritic spine pathology in Alzheimer’s disease: problems and opportunities

(2015) Mario M. Dorostkar et al.   ACTA NEUROPATHOLOGICA

Chemobrain: A critical review and causal hypothesis of link between cytokines and epigenetic reprogramming associated with chemotherapy

(2015) Xiao-Min Wang et al.   CYTOKINE

Tau deposition drives neuropathological, inflammatory and behavioral abnormalities independently of neuronal loss in a novel mouse model

(2015) Casey Cook et al.   HUMAN MOLECULAR GENETICS

Donepezil attenuates Aβ-associated mitochondrial dysfunction and reduces mitochondrial Aβ accumulation in vivo and in vitro

(2015) Chun Yan Ye et al.   NEUROPHARMACOLOGY

Chemotherapy, cognitive impairment and hippocampal toxicity

(2015) J. Dietrich et al.   NEUROSCIENCE

Alternatively activated microglia and macrophages in the central nervous system

(2015) Rafael Franco et al.   PROGRESS IN NEUROBIOLOGY

Obesity Elicits Interleukin 1-Mediated Deficits in Hippocampal Synaptic Plasticity

(2014) J. R. Erion et al.   JOURNAL OF NEUROSCIENCE

Disturbed mitochondrial dynamics and neurodegenerative disorders

(2014) Florence Burté et al.   Nature Reviews Neurology

Effects of vildagliptin versus sitagliptin, on cardiac function, heart rate variability and mitochondrial function in obese insulin-resistant rats

(2013) Nattayaporn Apaijai et al.   BRITISH JOURNAL OF PHARMACOLOGY

Brain inflammation induces post-synaptic changes during early synapse formation in adult-born hippocampal neurons

(2013) Deepti Chugh et al.   EXPERIMENTAL NEUROLOGY

Altered small-world properties of gray matter networks in breast cancer

(2012) S M Hadi Hosseini et al.   BMC Neurology

Reduced hippocampal volume and verbal memory performance associated with interleukin-6 and tumor necrosis factor-alpha levels in chemotherapy-treated breast cancer survivors

(2012) Shelli Kesler et al.   BRAIN BEHAVIOR AND IMMUNITY

Neurogenesis, inflammation and behavior

(2012) Rachel A. Kohman et al.   BRAIN BEHAVIOR AND IMMUNITY

Genomic Analysis of Reactive Astrogliosis

(2012) J. L. Zamanian et al.   JOURNAL OF NEUROSCIENCE

Effects of metformin on learning and memory behaviors and brain mitochondrial functions in high fat diet induced insulin resistant rats

(2012) Hiranya Pintana et al.   LIFE SCIENCES

Targeting the nicotinic alpha7 acetylcholine receptor to enhance cognition in disease

(2011) Tanya L. Wallace et al.   BIOCHEMICAL PHARMACOLOGY

Epicatechin attenuates doxorubicin-induced brain toxicity: Critical role of TNF-α, iNOS and NF-κB

(2011) Rasha H. Mohamed et al.   BRAIN RESEARCH BULLETIN

PPARγ Agonist Improves Neuronal Insulin Receptor Function in Hippocampus and Brain Mitochondria Function in Rats with Insulin Resistance Induced by Long Term High-Fat Diets

(2011) Noppamas Pipatpiboon et al.   ENDOCRINOLOGY

2-Mercaptoethane sulfonate prevents doxorubicin-induced plasma protein oxidation and TNF-α release: Implications for the reactive oxygen species-mediated mechanisms of chemobrain

(2011) Christopher D. Aluise et al.   FREE RADICAL BIOLOGY AND MEDICINE

Donepezil reduces cognitive impairment associated with anti-cancer drugs in a mouse model

(2011) Gordon Winocur et al.   NEUROPHARMACOLOGY

Microglia signaling as a target of donepezil

(2010) Jaegyu Hwang et al.   NEUROPHARMACOLOGY

Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease

(2009) X. Wang et al.   JOURNAL OF NEUROSCIENCE

Focal degeneration of astrocytes in amyotrophic lateral sclerosis

(2008) D Rossi et al.   CELL DEATH AND DIFFERENTIATION

Very rapid quantification of malondialdehyde (MDA) in rat brain exposed to lead, aluminium and phenolic antioxidants by high-performance liquid chromatography-fluorescence detection

(2008) N. Candan et al.   NEUROTOXICOLOGY