Down-regulation of astrocytic sonic hedgehog by activation of endothelin ETB receptors: Involvement in traumatic brain injury-induced disruption of blood brain barrier in a mouse model

Angiopoietin‐1/Tie‐2 signal after focal traumatic brain injury is potentiated by BQ788, an ET B receptor antagonist, in the mouse cerebrum: Involvement in recovery of blood–brain barrier function

(2020) Shotaro Michinaga et al.   JOURNAL OF NEUROCHEMISTRY

Activation of the Hedgehog Pathway Promotes Recovery of Neurological Function After Traumatic Brain Injury by Protecting the Neurovascular Unit

(2020) Jingchuan Wu et al.   Translational Stroke Research

Endothelin receptor antagonists alleviate blood-brain barrier disruption and cerebral edema in a mouse model of traumatic brain injury: A comparison between bosentan and ambrisentan

(2020) Shotaro Michinaga et al.   NEUROPHARMACOLOGY

Dual Roles of Astrocyte-Derived Factors in Regulation of Blood-Brain Barrier Function after Brain Damage

(2019) Shotaro Michinaga et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Matrix metalloproteinase-9 regulates the blood brain barrier via the hedgehog pathway in a rat model of traumatic brain injury

(2019) Mu-Yao Wu et al.   BRAIN RESEARCH

Delayed Administration of BQ788, an ETB Antagonist, after Experimental Traumatic Brain Injury Promotes Recovery of Blood–Brain Barrier Function and a Reduction of Cerebral Edema in Mice

(2018) Shotaro Michinaga et al.   JOURNAL OF NEUROTRAUMA

Wip1 regulates blood-brain barrier function and neuro-inflammation induced by lipopolysaccharide via the sonic hedgehog signaling signaling pathway

(2018) Hong Zhen et al.   MOLECULAR IMMUNOLOGY

Pathophysiology and treatment of cerebral edema in traumatic brain injury

(2018) Ruchira M. Jha et al.   NEUROPHARMACOLOGY

Administration of sonic hedgehog protein induces angiogenesis and has therapeutic effects after stroke in rats

(2017) Sheng-cai Chen et al.   NEUROSCIENCE

Glial-endothelial crosstalk regulates blood–brain barrier function

(2016) Lara Cheslow et al.   CURRENT OPINION IN PHARMACOLOGY

Cellular response of the blood-brain barrier to injury: Potential biomarkers and therapeutic targets for brain regeneration

(2016) M.M. Tenreiro et al.   NEUROBIOLOGY OF DISEASE

The pathophysiological role of astrocytic endothelin-1

(2016) Stéphanie Hostenbach et al.   PROGRESS IN NEUROBIOLOGY

VEGI attenuates the inflammatory injury and disruption of blood–brain barrier partly by suppressing the TLR4/NF-κB signaling pathway in experimental traumatic brain injury

(2015) Weiwei Gao et al.   BRAIN RESEARCH

Blood–brain barrier dysfunction following traumatic brain injury

(2015) Himakarnika Alluri et al.   METABOLIC BRAIN DISEASE

ETB receptor-mediated MMP-9 activation induces vasogenic edema via ZO-1 protein degradation following status epilepticus

(2015) J.Y. Kim et al.   NEUROSCIENCE

Notch1–STAT3–ETBRsignaling axis controls reactive astrocyte proliferation after brain injury

(2015) Matthew D. LeComte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Blood–Brain Barrier as a Target in Traumatic Brain Injury Treatment

(2014) Serge C. Thal et al.   ARCHIVES OF MEDICAL RESEARCH

MMP-9 Inhibitor SB-3CT Attenuates Behavioral Impairments and Hippocampal Loss after Traumatic Brain Injury in Rat

(2014) Feng Jia et al.   JOURNAL OF NEUROTRAUMA

Ablation of matrix metalloproteinase-9 gene decreases cerebrovascular permeability and fibrinogen deposition post traumatic brain injury in mice

(2014) Nino Muradashvili et al.   METABOLIC BRAIN DISEASE

A Smoothened receptor agonist is neuroprotective and promotes regeneration after ischemic brain injury

(2014) O V Chechneva et al.   Cell Death & Disease

Sonic Hedgehog (Shh) Regulates the Expression of Angiogenic Growth Factors in Oxygen–Glucose-Deprived Astrocytes by Mediating the Nuclear Receptor NR2F2

(2013) Yanan Li et al.   MOLECULAR NEUROBIOLOGY

Astrocyte-Derived Sonic Hedgehog Contributes to Angiogenesis in Brain Microvascular Endothelial Cells via RhoA/ROCK Pathway After Oxygen–Glucose Deprivation

(2013) Quan-Wei He et al.   MOLECULAR NEUROBIOLOGY

Endothelins reciprocally regulate VEGF-A and angiopoietin-1 production in cultured rat astrocytes: Implications on astrocytic proliferation

(2012) Yutaka Koyama et al.   GLIA

Blood–brain barrier permeability is positively correlated with cerebral microvascular perfusion in the early fluid percussion-injured brain of the rat

(2012) Yong Lin et al.   LABORATORY INVESTIGATION

Polydatin modulates inflammation by decreasing NF-κB activation and oxidative stress by increasing Gli1, Ptch1, SOD1 expression and ameliorates blood–brain barrier permeability for its neuroprotective effect in pMCAO rat brain

(2011) Hui Ji et al.   BRAIN RESEARCH BULLETIN

Na-K-Cl cotransporter-1 in the mechanism of cell swelling in cultured astrocytes after fluid percussion injury

(2011) Arumugam R. Jayakumar et al.   JOURNAL OF NEUROCHEMISTRY

Endogenous GFAP-Positive Neural Stem/Progenitor Cells in the Postnatal Mouse Cortex Are Activated following Traumatic Brain Injury

(2011) Aminul I. Ahmed et al.   JOURNAL OF NEUROTRAUMA

Differential effects of endothelin receptor A and B antagonism on behavioral outcome following traumatic brain injury

(2011) Christian A Reynolds et al.   NEUROLOGICAL RESEARCH

I.c.v administration of an endothelin ETB receptor agonist stimulates vascular endothelial growth factor-A production and activates vascular endothelial growth factor receptors in rat brain

(2011) Y. Koyama et al.   NEUROSCIENCE

Inhibition of sonic hedgehog signaling aggravates brain damage associated with the down-regulation of Gli1, Ptch1 and SOD1 expression in acute ischemic stroke

(2011) Hui Ji et al.   NEUROSCIENCE LETTERS

The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence

(2011) J. I. Alvarez et al.   SCIENCE

Endothelin-1 Is Increased in Cerebrospinal Fluid and Associated with Unfavorable Outcomes in Children after Severe Traumatic Brain Injury

(2010) Rosanne Salonia et al.   JOURNAL OF NEUROTRAUMA

Intracerebroventricular Administration of an Endothelin ETB–Receptor Agonist Increases Expression of Matrix Metalloproteinase-2 and -9 in Rat Brain

(2010) Yutaka Koyama et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Juguloarterial Endothelin-1 Gradients After Severe Traumatic Brain Injury

(2010) Doris A. Chatfield et al.   Neurocritical Care

Amelioration of hypoperfusion after traumatic brain injury by in vivo endothelin-1 knockout

(2009) Theodor Petrov   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY