标题
New approaches for brain repair—from rescue to reprogramming
作者
关键词
-
出版物
NATURE
Volume 557, Issue 7705, Pages 329-334
出版商
Springer Nature
发表日期
2018-05-08
DOI
10.1038/s41586-018-0087-1
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Human Neural Stem Cell Transplantation Rescues Functional Deficits in R6/2 and Q140 Huntington's Disease Mice
- (2018) Jack C. Reidling et al. Stem Cell Reports
- Synthetic AAV/CRISPR vectors for blocking HIV-1 expression in persistently infected astrocytes
- (2017) Christine Kunze et al. GLIA
- Human iPS cell-derived dopaminergic neurons function in a primate Parkinson’s disease model
- (2017) Tetsuhiro Kikuchi et al. NATURE
- Neurotoxic reactive astrocytes are induced by activated microglia
- (2017) Shane A. Liddelow et al. NATURE
- HLA-E-expressing pluripotent stem cells escape allogeneic responses and lysis by NK cells
- (2017) Germán G Gornalusse et al. NATURE BIOTECHNOLOGY
- Induction of functional dopamine neurons from human astrocytes in vitro and mouse astrocytes in a Parkinson's disease model
- (2017) Pia Rivetti di Val Cervo et al. NATURE BIOTECHNOLOGY
- The diversity and disparity of the glial scar
- (2017) Katrina L. Adams et al. NATURE NEUROSCIENCE
- Antibody recognizing 4-sulfated chondroitin sulfate proteoglycans restores memory in tauopathy-induced neurodegeneration
- (2017) Sujeong Yang et al. NEUROBIOLOGY OF AGING
- Clinical tests of neurotrophic factors for human neurodegenerative diseases, part 2: Where do we stand and where must we go next?
- (2017) Raymond T. Bartus et al. NEUROBIOLOGY OF DISEASE
- Clinical tests of neurotrophic factors for human neurodegenerative diseases, part 1: Where have we been and what have we learned?
- (2017) Raymond T. Bartus et al. NEUROBIOLOGY OF DISEASE
- Hallmarks of Alzheimer’s Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain
- (2017) Ira Espuny-Camacho et al. NEURON
- MHC matching improves engraftment of iPSC-derived neurons in non-human primates
- (2017) Asuka Morizane et al. Nature Communications
- Direct Reprogramming of Resident NG2 Glia into Neurons with Properties of Fast-Spiking Parvalbumin-Containing Interneurons
- (2017) Maria Pereira et al. Stem Cell Reports
- Neuroprotective Effects of Physical Activity: Evidence from Human and Animal Studies
- (2017) Sergio Chieffi et al. Frontiers in Neurology
- Neurogenesis and Gliogenesis in Nervous System Plasticity and Repair
- (2016) Jonas Frisén Annual Review of Cell and Developmental Biology
- Adult Neurogenesis in Mammals: Variations and Confusions
- (2016) Hans-Peter Lipp et al. BRAIN BEHAVIOR AND EVOLUTION
- Chemical Control of Grafted Human PSC-Derived Neurons in a Mouse Model of Parkinson’s Disease
- (2016) Yuejun Chen et al. Cell Stem Cell
- Identification and Successful Negotiation of a Metabolic Checkpoint in Direct Neuronal Reprogramming
- (2016) Sergio Gascón et al. Cell Stem Cell
- Direct neuronal reprogramming: learning from and for development
- (2016) Giacomo Masserdotti et al. DEVELOPMENT
- Human neural progenitors differentiate into astrocytes and protect motor neurons in aging rats
- (2016) Melanie M. Das et al. EXPERIMENTAL NEUROLOGY
- Systemic application of AAV vectors targeting GFAP-expressing astrocytes in Z -Q175-KI Huntington's disease mice
- (2016) Tatyana Vagner et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Transplanted embryonic neurons integrate into adult neocortical circuits
- (2016) Susanne Falkner et al. NATURE
- Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain
- (2016) Benjamin E Deverman et al. NATURE BIOTECHNOLOGY
- Developing therapeutically more efficient Neurturin variants for treatment of Parkinson's disease
- (2016) Pia Runeberg-Roos et al. NEUROBIOLOGY OF DISEASE
- DREADD Modulation of Transplanted DA Neurons Reveals a Novel Parkinsonian Dyskinesia Mechanism Mediated by the Serotonin 5-HT6 Receptor
- (2016) Patrick Aldrin-Kirk et al. NEURON
- Extensive graft-derived dopaminergic innervation is maintained 24 years after transplantation in the degenerating parkinsonian brain
- (2016) Wen Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Gene delivery of neurturin to putamen and substantia nigra in Parkinson disease: A double-blind, randomized, controlled trial
- (2015) C. Warren Olanow et al. ANNALS OF NEUROLOGY
- Small Molecules Efficiently Reprogram Human Astroglial Cells into Functional Neurons
- (2015) Lei Zhang et al. Cell Stem Cell
- Brain size and limits to adult neurogenesis
- (2015) Mercedes F. Paredes et al. JOURNAL OF COMPARATIVE NEUROLOGY
- Ascl1 Converts Dorsal Midbrain Astrocytes into Functional Neurons In Vivo
- (2015) Y. Liu et al. JOURNAL OF NEUROSCIENCE
- Optogenetics enables functional analysis of human embryonic stem cell–derived grafts in a Parkinson's disease model
- (2015) Julius A Steinbeck et al. NATURE BIOTECHNOLOGY
- Cell-based therapies for Parkinson disease—past insights and future potential
- (2015) Roger A. Barker et al. Nature Reviews Neurology
- Post-mortem assessment of the short and long-term effects of the trophic factor neurturin in patients with α-synucleinopathies
- (2015) R.T. Bartus et al. NEUROBIOLOGY OF DISEASE
- Area-Specific Reestablishment of Damaged Circuits in the Adult Cerebral Cortex by Cortical Neurons Derived from Mouse Embryonic Stem Cells
- (2015) Kimmo A. Michelsen et al. NEURON
- Moving Stem Cells to the Clinic: Potential and Limitations for Brain Repair
- (2015) Julius A. Steinbeck et al. NEURON
- In Vivo Reprogramming of Striatal NG2 Glia into Functional Neurons that Integrate into Local Host Circuitry
- (2015) Olof Torper et al. Cell Reports
- Monosynaptic Tracing using Modified Rabies Virus Reveals Early and Extensive Circuit Integration of Human Embryonic Stem Cell-Derived Neurons
- (2015) Shane Grealish et al. Stem Cell Reports
- SOX2 Reprograms Resident Astrocytes into Neural Progenitors in the Adult Brain
- (2015) Wenze Niu et al. Stem Cell Reports
- Mutant huntingtin is present in neuronal grafts in huntington disease patients
- (2014) Francesca Cicchetti et al. ANNALS OF NEUROLOGY
- Neurogenesis in the Striatum of the Adult Human Brain
- (2014) Aurélie Ernst et al. CELL
- Human ESC-Derived Dopamine Neurons Show Similar Preclinical Efficacy and Potency to Fetal Neurons when Grafted in a Rat Model of Parkinson’s Disease
- (2014) Shane Grealish et al. Cell Stem Cell
- Human and Monkey Striatal Interneurons Are Derived from the Medial Ganglionic Eminence But Not from the Adult Subventricular Zone
- (2014) C. Wang et al. JOURNAL OF NEUROSCIENCE
- Fetal-cell revival for Parkinson’s
- (2014) Alison Abbott NATURE
- Glial Cells as Progenitors and Stem Cells: New Roles in the Healthy and Diseased Brain
- (2014) Leda Dimou et al. PHYSIOLOGICAL REVIEWS
- Cortical plasticity induced by transplantation of embryonic somatostatin or parvalbumin interneurons
- (2014) Yunshuo Tang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A latent neurogenic program in astrocytes regulated by Notch signaling in the mouse
- (2014) J. P. Magnusson et al. SCIENCE
- Sox2-Mediated Conversion of NG2 Glia into Induced Neurons in the Injured Adult Cerebral Cortex
- (2014) Christophe Heinrich et al. Stem Cell Reports
- Striatal allografts in patients with Huntington’s disease: impact of diminished astrocytes and vascularization on graft viability
- (2013) Giulia Cisbani et al. BRAIN
- In Vivo Direct Reprogramming of Reactive Glial Cells into Functional Neurons after Brain Injury and in an Alzheimer’s Disease Model
- (2013) Ziyuan Guo et al. Cell Stem Cell
- The long-term safety and efficacy of bilateral transplantation of human fetal striatal tissue in patients with mild to moderate Huntington's disease
- (2013) R. A. Barker et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Protective astrogenesis from the SVZ niche after injury is controlled by Notch modulator Thbs4
- (2013) Eric J. Benner et al. NATURE
- Auto-attraction of neural precursors and their neuronal progeny impairs neuronal migration
- (2013) Julia Ladewig et al. NATURE NEUROSCIENCE
- Pyramidal Neurons Derived from Human Pluripotent Stem Cells Integrate Efficiently into Mouse Brain Circuits In Vivo
- (2013) Ira Espuny-Camacho et al. NEURON
- Review: The fate of cell grafts for the treatment of Huntington's disease: thepost-mortemevidence
- (2013) G. Cisbani et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Generation of induced neurons via direct conversion in vivo
- (2013) O. Torper et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human Pluripotent Stem Cell Differentiation into Authentic Striatal Projection Neurons
- (2013) Alessia Delli Carri et al. Stem Cell Reviews and Reports
- Environmental impact on direct neuronal reprogramming in vivo in the adult brain
- (2013) Andrew Grande et al. Nature Communications
- Enhancement of Polysialic Acid Expression Improves Function of Embryonic Stem-Derived Dopamine Neuron Grafts in Parkinsonian Mice
- (2013) Daniela Battista et al. Stem Cells Translational Medicine
- Long-term Clinical Outcome of Fetal Cell Transplantation for Parkinson Disease
- (2013) Zinovia Kefalopoulou et al. JAMA Neurology
- Human Embryonic Stem Cell-Derived GABA Neurons Correct Locomotion Deficits in Quinolinic Acid-Lesioned Mice
- (2012) Lixiang Ma et al. Cell Stem Cell
- Reprogramming of Pericyte-Derived Cells of the Adult Human Brain into Induced Neuronal Cells
- (2012) Marisa Karow et al. Cell Stem Cell
- Fetal dopaminergic transplantation trials and the future of neural grafting in Parkinson's disease
- (2012) Roger A Barker et al. LANCET NEUROLOGY
- -Synuclein-Induced Down-Regulation of Nurr1 Disrupts GDNF Signaling in Nigral Dopamine Neurons
- (2012) M. Decressac et al. Science Translational Medicine
- Generation of Regionally Specified Neural Progenitors and Functional Neurons from Human Embryonic Stem Cells under Defined Conditions
- (2012) Agnete Kirkeby et al. Cell Reports
- Induction of human neuronal cells by defined transcription factors
- (2011) Zhiping P. Pang et al. NATURE
- Direct conversion of human fibroblasts to dopaminergic neurons
- (2011) U. Pfisterer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Gene delivery of AAV2-neurturin for Parkinson's disease: a double-blind, randomised, controlled trial
- (2010) William J Marks et al. LANCET NEUROLOGY
- Cortical Plasticity Induced by Inhibitory Neuron Transplantation
- (2010) D. G. Southwell et al. SCIENCE
- Serotonergic Neurons Mediate Dyskinesia Side Effects in Parkinson's Patients with Neural Transplants
- (2010) M. Politis et al. Science Translational Medicine
- Modulation of Fate Determinants Olig2 and Pax6 in Resident Glia Evokes Spiking Neuroblasts in a Model of Mild Brain Ischemia
- (2010) Golo Kronenberg et al. STROKE
- Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation
- (2008) Jia-Yi Li et al. NATURE MEDICINE
- Focal transplantation–based astrocyte replacement is neuroprotective in a model of motor neuron disease
- (2008) Angelo C Lepore et al. NATURE NEUROSCIENCE
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