标题
Organoboron Compounds: Effective Antibacterial and Antiparasitic Agents
作者
关键词
-
出版物
MOLECULES
Volume 26, Issue 11, Pages 3309
出版商
MDPI AG
发表日期
2021-06-01
DOI
10.3390/molecules26113309
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- What constitutes a neglected tropical disease?
- (2020) Peter J. Hotez et al. PLoS Neglected Tropical Diseases
- Research funding after COVID-19
- (2020) Miguel Prudêncio et al. Nature Microbiology
- Boronic Acids and Their Derivatives in Medicinal Chemistry: Synthesis and Biological Applications
- (2020) Mariana Pereira Silva et al. MOLECULES
- Cuts in cancer research funding due to COVID-19
- (2020) Talha Khan Burki LANCET ONCOLOGY
- Boron-Pleuromutilins as Anti-Wolbachia Agents with Potential for Treatment of Onchocerciasis and Lymphatic Filariasis
- (2019) Robert T. Jacobs et al. JOURNAL OF MEDICINAL CHEMISTRY
- Boron in drug design: Recent advances in the development of new therapeutic agents
- (2019) Guilherme Felipe Santos Fernandes et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Leishmania parasites are inhibited by the benzoxaborole AN2690 targeting leucyl-tRNA synthetase
- (2018) Reetika Manhas et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Topical Treatment for Cutaneous Leishmaniasis: Dermato-Pharmacokinetic Lead Optimization of Benzoxaboroles
- (2018) Katrien Van Bocxlaer et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Aminoacyl-tRNA synthetases, therapeutic targets for infectious diseases
- (2018) Eun-Young Lee et al. BIOCHEMICAL PHARMACOLOGY
- Hit Generation in TB Drug Discovery: From Genome to Granuloma
- (2018) Tianao Yuan et al. CHEMICAL REVIEWS
- Benzoxaborole compounds for therapeutic uses: a patent review (2010- 2018)
- (2018) Alessio Nocentini et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Benzoboroxoles: Synthesis and applications in medicinal chemistry
- (2018) Gautam R. Mereddy et al. JOURNAL OF ORGANOMETALLIC CHEMISTRY
- Accelerating the development of therapeutic strategies for drug-resistant tuberculosis
- (2018) Michael J. Vjecha et al. NATURE REVIEWS DRUG DISCOVERY
- The 7-phenyl benzoxaborole series is active against Mycobacterium tuberculosis
- (2018) Aaron Korkegian et al. TUBERCULOSIS
- Synthesis of biologically active boron-containing compounds
- (2018) Fei Yang et al. MedChemComm
- Relapse of Visceral Leishmaniasis after Miltefosine Treatment in a Nepalese Patient
- (2018) Basu Dev Pandey et al. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
- The Current Status and Perspectives of Delivery Strategy for Boron-based Drugs
- (2018) Zhu Yinghuai et al. CURRENT MEDICINAL CHEMISTRY
- Cinnamoyl-Oxaborole Amides: Synthesis and Their in Vitro Biological Activity
- (2018) Maureen Gumbo et al. MOLECULES
- A high throughput screen for next-generation leads targeting malaria parasite transmission
- (2018) Michael J. Delves et al. Nature Communications
- Carbonic anhydrases from Trypanosoma cruzi and Leishmania donovani chagasi are inhibited by benzoxaboroles
- (2017) Alessio Nocentini et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- Benzoxaborole Antimalarial Agents. Part 5. Lead Optimization of Novel Amide Pyrazinyloxy Benzoxaboroles and Identification of a Preclinical Candidate
- (2017) Yong-Kang Zhang et al. JOURNAL OF MEDICINAL CHEMISTRY
- Discovery of a Potent and Specific M. tuberculosis Leucyl-tRNA Synthetase Inhibitor: (S)-3-(Aminomethyl)-4-chloro-7-(2-hydroxyethoxy)benzo[c][1,2]oxaborol-1(3H)-ol (GSK656)
- (2017) Xianfeng Li et al. JOURNAL OF MEDICINAL CHEMISTRY
- Limitations of Current Therapeutic Options, Possible Drug Targets and Scope of Natural Products in Control of Leishmaniasis
- (2017) Neeraj Tiwari et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- A potent antimalarial benzoxaborole targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue
- (2017) Ebere Sonoiki et al. Nature Communications
- Bortezomib Warhead-Switch Confers Dual Activity against Mycobacterial Caseinolytic Protease and Proteasome and Selectivity against Human Proteasome
- (2017) Wilfried Moreira et al. Frontiers in Microbiology
- Discovery of Novel Oral Protein Synthesis Inhibitors of Mycobacterium tuberculosis That Target Leucyl-tRNA Synthetase
- (2016) Andrés Palencia et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Antimalarial Benzoxaboroles Target Plasmodium falciparum Leucyl-tRNA Synthetase
- (2016) Ebere Sonoiki et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Cryptosporidium and Toxoplasma Parasites Are Inhibited by a Benzoxaborole Targeting Leucyl-tRNA Synthetase
- (2016) Andrés Palencia et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Synthesis and evaluation of functionalized benzoboroxoles as potential anti -tuberculosis agents
- (2016) Mohammad A. Alam et al. TETRAHEDRON
- Characterization of the Dynamic Equilibrium between Closed and Open Forms of the Benzoxaborole Pharmacophore
- (2016) Sergey Vshyvenko et al. ACS Medicinal Chemistry Letters
- Boromycin Kills Mycobacterial Persisters without Detectable Resistance
- (2016) Wilfried Moreira et al. Frontiers in Microbiology
- Recent Developments in the Chemistry and Biological Applications of Benzoxaboroles
- (2015) Agnieszka Adamczyk-Woźniak et al. CHEMICAL REVIEWS
- Bacterial, fungal and protozoan carbonic anhydrases as drug targets
- (2015) Clemente Capasso et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Benzoxaborole Antimalarial Agents. Part 4. Discovery of Potent 6-(2-(Alkoxycarbonyl)pyrazinyl-5-oxy)-1,3-dihydro-1-hydroxy-2,1-benzoxaboroles
- (2015) Yong-Kang Zhang et al. JOURNAL OF MEDICINAL CHEMISTRY
- Type-II NADH:quinone oxidoreductase from Staphylococcus aureushas two distinct binding sites and is rate limited by quinone reduction
- (2015) Filipa V. Sena et al. MOLECULAR MICROBIOLOGY
- Understanding artemisinin resistance
- (2015) C. H. Sibley SCIENCE
- Target Mechanism-Based Whole-Cell Screening Identifies Bortezomib as an Inhibitor of Caseinolytic Protease in Mycobacteria
- (2015) Wilfried Moreira et al. mBio
- Mycobacterium tuberculosis Type II NADH-Menaquinone Oxidoreductase Catalyzes Electron Transfer through a Two-Site Ping-Pong Mechanism and Has Two Quinone-Binding Sites
- (2014) Takahiro Yano et al. BIOCHEMISTRY
- Synthesis, Characterization, and Antibacterial Activity of Structurally Complex 2-Acylated 2,3,1-Benzodiazaborines and Related Compounds
- (2014) Divya Kanichar et al. CHEMISTRY & BIODIVERSITY
- Novel pyrrolobenzoxaboroles: Design, synthesis, and biological evaluation against Trypanosoma brucei
- (2014) Puhua Wu et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Efficacy and Safety of Amphotericin B Emulsion versus Liposomal Formulation in Indian Patients with Visceral Leishmaniasis: A Randomized, Open-Label Study
- (2014) Shyam Sundar et al. PLoS Neglected Tropical Diseases
- Post-Translational Regulation via Clp Protease Is Critical for Survival of Mycobacterium tuberculosis
- (2014) Ravikiran M. Raju et al. PLoS Pathogens
- Boron chemicals in diagnosis and therapeutics
- (2013) Bhaskar C Das et al. Future Medicinal Chemistry
- Bacterial caseinolytic proteases as novel targets for antibacterial treatment
- (2013) Heike Brötz-Oesterhelt et al. INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY
- Global Causes of Diarrheal Disease Mortality in Children
- (2013) Claudio F. Lanata et al. PLoS One
- The synthesis of benzoxaboroles and their applications in medicinal chemistry
- (2013) Jiong Zhang et al. Science China-Chemistry
- Discovery of a potent benzoxaborole-based anti-pneumococcal agent targeting leucyl-tRNA synthetase
- (2013) Qing-Hua Hu et al. Scientific Reports
- Aminoacyl-tRNA Synthetase Inhibitors As Potent Antibacterials
- (2012) P.-C Lv et al. CURRENT MEDICINAL CHEMISTRY
- New therapeutic options for onychomycosis
- (2012) Aditya K Gupta et al. EXPERT OPINION ON PHARMACOTHERAPY
- Chalcone–Benzoxaborole Hybrid Molecules as Potent Antitrypanosomal Agents
- (2012) Zhitao Qiao et al. JOURNAL OF MEDICINAL CHEMISTRY
- The life cycle of Trypanosoma (Nannomonas) congolense in the tsetse fly
- (2012) Lori Peacock et al. Parasites & Vectors
- Mycobacterium tuberculosis ClpP1 and ClpP2 Function Together in Protein Degradation and Are Required for Viability in vitro and During Infection
- (2012) Ravikiran M. Raju et al. PLoS Pathogens
- Benzoxaborole antimalarial agents. Part 2: Discovery of fluoro-substituted 7-(2-carboxyethyl)-1,3-dihydro-1-hydroxy-2,1-benzoxaboroles
- (2011) Yong-Kang Zhang et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Carbaboranes as Pharmacophores: Properties, Synthesis, and Application Strategies
- (2011) Matthias Scholz et al. CHEMICAL REVIEWS
- Boron-containing inhibitors of synthetases
- (2011) Stephen J. Baker et al. CHEMICAL SOCIETY REVIEWS
- In Vitro and In Vivo Selective Antitumor Activity of a Novel Orally Bioavailable Proteasome Inhibitor MLN9708 against Multiple Myeloma Cells
- (2011) Dharminder Chauhan et al. CLINICAL CANCER RESEARCH
- Bortezomib as the First Proteasome Inhibitor Anticancer Drug: Current Status and Future Perspectives
- (2011) D. Chen et al. CURRENT CANCER DRUG TARGETS
- Boron-based drugs as antiprotozoals
- (2011) Robert T. Jacobs et al. CURRENT OPINION IN INFECTIOUS DISEASES
- Benzoxaboroles: a new class of potential drugs for human African trypanosomiasis
- (2011) Robert T Jacobs et al. Future Medicinal Chemistry
- Design, Synthesis, and Structure−Activity Relationship ofTrypanosoma bruceiLeucyl-tRNA Synthetase Inhibitors as Antitrypanosomal Agents
- (2011) Dazhong Ding et al. JOURNAL OF MEDICINAL CHEMISTRY
- Topological Principles of Borosilicate Glass Chemistry
- (2011) Morten M. Smedskjaer et al. JOURNAL OF PHYSICAL CHEMISTRY B
- An efficient synthesis for a new class antimalarial agent, 7-(2-carboxyethyl)-1,3-dihydro-1-hydroxy-2,1-benzoxaborole
- (2011) Yong-Kang Zhang et al. TETRAHEDRON LETTERS
- SCYX-7158, an Orally-Active Benzoxaborole for the Treatment of Stage 2 Human African Trypanosomiasis
- (2011) Robert T. Jacobs et al. PLoS Neglected Tropical Diseases
- Discovery of Novel Orally Bioavailable Oxaborole 6-Carboxamides That Demonstrate Cure in a Murine Model of Late-Stage Central Nervous System African Trypanosomiasis
- (2010) B. Nare et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Synthesis and structure–activity relationships of novel benzoxaboroles as a new class of antimalarial agents
- (2010) Yong-Kang Zhang et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Natural and Synthetic Small Boron-Containing Molecules as Potential Inhibitors of Bacterial and Fungal Quorum Sensing
- (2010) Valery M. Dembitsky et al. CHEMICAL REVIEWS
- Synthesis, in Vitro and in Vivo Biological Evaluation, and Comprehensive Understanding of Structure−Activity Relationships of Dipeptidyl Boronic Acid Proteasome Inhibitors Constructed from β-Amino Acids
- (2010) Yongqiang Zhu et al. JOURNAL OF MEDICINAL CHEMISTRY
- Discovery of Novel Benzoxaborole-Based Potent Antitrypanosomal Agents
- (2010) Dazhong Ding et al. ACS Medicinal Chemistry Letters
- Therapeutic potential of boron-containing compounds
- (2009) Stephen J Baker et al. Future Medicinal Chemistry
- Crystal Structures of the Human and Fungal Cytosolic Leucyl-tRNA Synthetase Editing Domains: A Structural Basis for the Rational Design of Antifungal Benzoxaboroles
- (2009) Elena Seiradake et al. JOURNAL OF MOLECULAR BIOLOGY
- Benzoxaboroles – Old compounds with new applications
- (2009) Agnieszka Adamczyk-Woźniak et al. JOURNAL OF ORGANOMETALLIC CHEMISTRY
- Biology oftrans-Translation
- (2008) Kenneth C. Keiler Annual Review of Microbiology
- Synthesis, Characterization, and Antifungal Activity of Boron-Containing Thiosemicarbazones
- (2008) Justin W. Hicks et al. CHEMISTRY & BIODIVERSITY
- Synthesis, Cytotoxicity, and Anti-Trypanosoma cruziActivity of New Chalcones
- (2008) José C. Aponte et al. JOURNAL OF MEDICINAL CHEMISTRY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started