标题
Crystal structure of the human 5-HT1B serotonin receptor bound to an inverse agonist
作者
关键词
-
出版物
Cell Discovery
Volume 4, Issue 1, Pages -
出版商
Springer Nature
发表日期
2018-03-09
DOI
10.1038/s41421-018-0009-2
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Crystal Structure of the Human Cannabinoid Receptor CB 1
- (2016) Tian Hua et al. CELL
- Structure-Based Discovery of Novel and Selective 5-Hydroxytryptamine 2B Receptor Antagonists for the Treatment of Irritable Bowel Syndrome
- (2016) Yu Zhou et al. JOURNAL OF MEDICINAL CHEMISTRY
- Structure of the adenosine A2A receptor bound to an engineered G protein
- (2016) Byron Carpenter et al. NATURE
- Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region
- (2016) A. J. Venkatakrishnan et al. NATURE
- MDTraj: A Modern Open Library for the Analysis of Molecular Dynamics Trajectories
- (2015) Robert T. McGibbon et al. BIOPHYSICAL JOURNAL
- Two disparate ligand-binding sites in the human P2Y1 receptor
- (2015) Dandan Zhang et al. NATURE
- Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser
- (2015) Yanyong Kang et al. NATURE
- Epock: rapid analysis of protein pocket dynamics
- (2014) Benoist Laurent et al. BIOINFORMATICS
- Crystal structure of the human OX2 orexin receptor bound to the insomnia drug suvorexant
- (2014) Jie Yin et al. NATURE
- Structure of the human P2Y12 receptor in complex with an antithrombotic drug
- (2014) Kaihua Zhang et al. NATURE
- Modified T4 Lysozyme Fusion Proteins Facilitate G Protein-Coupled Receptor Crystallogenesis
- (2014) Thor Seneca Thorsen et al. STRUCTURE
- CHARMM36 all-atom additive protein force field: Validation based on comparison to NMR data
- (2013) Jing Huang et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- Molecular signatures of G-protein-coupled receptors
- (2013) A. J. Venkatakrishnan et al. NATURE
- Improved low-resolution crystallographic refinement with Phenix and Rosetta
- (2013) Frank DiMaio et al. NATURE METHODS
- Structural Basis for Molecular Recognition at Serotonin Receptors
- (2013) C. Wang et al. SCIENCE
- Structural Features for Functional Selectivity at Serotonin Receptors
- (2013) D. Wacker et al. SCIENCE
- Ice breaking in GPCR structural biology
- (2012) Qiang Zhao et al. ACTA PHARMACOLOGICA SINICA
- Structure-Function of the G Protein–Coupled Receptor Superfamily
- (2012) Vsevolod Katritch et al. Annual Review of Pharmacology and Toxicology
- Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist
- (2012) Kazuko Haga et al. NATURE
- Structure of the agonist-bound neurotensin receptor
- (2012) Jim F. White et al. NATURE
- Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
- (2012) Aashish Manglik et al. NATURE
- Automated design of ligands to polypharmacological profiles
- (2012) Jérémy Besnard et al. NATURE
- Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions
- (2012) W. Liu et al. SCIENCE
- Fusion Partner Toolchest for the Stabilization and Crystallization of G Protein-Coupled Receptors
- (2012) Eugene Chun et al. STRUCTURE
- Efficient time-dependent density functional theory approximations for hybrid density functionals: Analytical gradients and parallelization
- (2011) Taras Petrenko et al. JOURNAL OF CHEMICAL PHYSICS
- SwissParam: A fast force field generation tool for small organic molecules
- (2011) Vincent Zoete et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- Crystal Structure-Based Virtual Screening for Fragment-like Ligands of the Human Histamine H1Receptor
- (2011) Chris de Graaf et al. JOURNAL OF MEDICINAL CHEMISTRY
- Crystal structure of the β2 adrenergic receptor–Gs protein complex
- (2011) Søren G. F. Rasmussen et al. NATURE
- Integration, scaling, space-group assignment and post-refinement
- (2010) Wolfgang Kabsch ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- XDS
- (2010) Wolfgang Kabsch ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Super-resolution biomolecular crystallography with low-resolution data
- (2010) Gunnar F. Schröder et al. NATURE
- Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists
- (2010) B. Wu et al. SCIENCE
- The Expanded Biology of Serotonin
- (2009) Miles Berger et al. Annual Review of Medicine
- Crystallizing membrane proteins using lipidic mesophases
- (2009) Martin Caffrey et al. Nature Protocols
- Multiple Switches in G Protein-Coupled Receptor Activation
- (2009) Shivani Ahuja et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Discovery and Structure−Activity Relationship of (1R)-8-Chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine (Lorcaserin), a Selective Serotonin 5-HT2CReceptor Agonist for the Treatment of Obesity
- (2007) Brian M. Smith et al. JOURNAL OF MEDICINAL CHEMISTRY
- Stabilization of the Human β2-Adrenergic Receptor TM4–TM3–TM5 Helix Interface by Mutagenesis of Glu1223.41, A Critical Residue in GPCR Structure
- (2007) Christopher B. Roth et al. JOURNAL OF MOLECULAR BIOLOGY
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