RADX prevents genome instability by confining replication fork reversal to stalled forks
出版年份 2021 全文链接
标题
RADX prevents genome instability by confining replication fork reversal to stalled forks
作者
关键词
DNA damage, DNA replication, telomere, electron microscopy, DNA repair, BRCA2, genome instability
出版物
MOLECULAR CELL
Volume 81, Issue 14, Pages 3007-3017.e5
出版商
Elsevier BV
发表日期
2021-06-08
DOI
10.1016/j.molcel.2021.05.014
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- RADX controls RAD51 filament dynamics to regulate replication fork stability
- (2021) Madison B. Adolph et al. MOLECULAR CELL
- DCAF14 promotes stalled fork stability to maintain genome integrity
- (2021) Arik Townsend et al. Cell Reports
- The plasticity of DNA replication forks in response to clinically relevant genotoxic stress
- (2020) Matteo Berti et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Sequential role of RAD51 paralog complexes in replication fork remodeling and restart
- (2020) Matteo Berti et al. Nature Communications
- Rad52 prevents excessive replication fork reversal and protects from nascent strand degradation
- (2019) Eva Malacaria et al. Nature Communications
- Replication-Coupled DNA Repair
- (2019) David Cortez MOLECULAR CELL
- Stabilization of Reversed Replication Forks by Telomerase Drives Telomere Catastrophe
- (2018) Pol Margalef et al. CELL
- RPA and RAD51: fork reversal, fork protection, and genome stability
- (2018) Kamakoti P. Bhat et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- RPA and RAD51: fork reversal, fork protection, and genome stability
- (2018) Kamakoti P. Bhat et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- RADX Modulates RAD51 Activity to Control Replication Fork Protection
- (2018) Kamakoti P. Bhat et al. Cell Reports
- Abro1 maintains genome stability and limits replication stress by protecting replication fork stability
- (2017) Shengfeng Xu et al. GENES & DEVELOPMENT
- Restoration of Replication Fork Stability in BRCA1- and BRCA2-Deficient Cells by Inactivation of SNF2-Family Fork Remodelers
- (2017) Angelo Taglialatela et al. MOLECULAR CELL
- RADX Promotes Genome Stability and Modulates Chemosensitivity by Regulating RAD51 at Replication Forks
- (2017) Huzefa Dungrawala et al. MOLECULAR CELL
- Smarcal1-Mediated Fork Reversal Triggers Mre11-Dependent Degradation of Nascent DNA in the Absence of Brca2 and Stable Rad51 Nucleofilaments
- (2017) Arun Mouli Kolinjivadi et al. MOLECULAR CELL
- MRE11 and EXO1 nucleases degrade reversed forks and elicit MUS81-dependent fork rescue in BRCA2-deficient cells
- (2017) Delphine Lemaçon et al. Nature Communications
- Replication fork reversal triggers fork degradation in BRCA2-defective cells
- (2017) Sofija Mijic et al. Nature Communications
- A Selective Small Molecule DNA2 Inhibitor for Sensitization of Human Cancer Cells to Chemotherapy
- (2016) Wenpeng Liu et al. EBioMedicine
- DNA2 drives processing and restart of reversed replication forks in human cells
- (2015) Saravanabhavan Thangavel et al. JOURNAL OF CELL BIOLOGY
- Rad51-mediated replication fork reversal is a global response to genotoxic treatments in human cells
- (2015) Ralph Zellweger et al. JOURNAL OF CELL BIOLOGY
- BOD1L Is Required to Suppress Deleterious Resection of Stressed Replication Forks
- (2015) Martin R. Higgs et al. MOLECULAR CELL
- A Dominant Mutation in Human RAD51 Reveals Its Function in DNA Interstrand Crosslink Repair Independent of Homologous Recombination
- (2015) Anderson T. Wang et al. MOLECULAR CELL
- High-affinity DNA-binding Domains of Replication Protein A (RPA) Direct SMARCAL1-dependent Replication Fork Remodeling
- (2015) Kamakoti P. Bhat et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- ATR phosphorylates SMARCAL1 to prevent replication fork collapse
- (2013) F. B. Couch et al. GENES & DEVELOPMENT
- Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition
- (2013) Matteo Berti et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Substrate-Selective Repair and Restart of Replication Forks by DNA Translocases
- (2013) Rémy Bétous et al. Cell Reports
- The Intra-S Phase Checkpoint Targets Dna2 to Prevent Stalled Replication Forks from Reversing
- (2012) Jiazhi Hu et al. CELL
- SMARCAL1 catalyzes fork regression and Holliday junction migration to maintain genome stability during DNA replication
- (2012) R. Betous et al. GENES & DEVELOPMENT
- Double-Strand Break Repair-Independent Role for BRCA2 in Blocking Stalled Replication Fork Degradation by MRE11
- (2011) Katharina Schlacher et al. CELL
- Less Is More:Neisseria gonorrhoeaeRecX Protein Stimulates Recombination by Inhibiting RecA
- (2010) Marielle C. Gruenig et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Rad51 protects nascent DNA from Mre11-dependent degradation and promotes continuous DNA synthesis
- (2010) Yoshitami Hashimoto et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The annealing helicase SMARCAL1 maintains genome integrity at stalled replication forks
- (2009) C. E. Bansbach et al. GENES & DEVELOPMENT
- A forward chemical genetic screen reveals an inhibitor of the Mre11–Rad50–Nbs1 complex
- (2008) Aude Dupré et al. Nature Chemical Biology
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