Supercritical Fluid-Based Decellularization Technologies for Regenerative Medicine Applications

Supercritical fluid-based extraction technologies are currently being increasingly utilized in high purity extract products for food industries. In recent years, supercritical fluid-based extraction technology is transformed in biomaterials process fields to be further utilized for tissue engineering and other biomedical applications. In particular, supercritical fluid-based decellularization protocols have great advantage over the conventional decellularization as it may allow preservation of extracellular matrix components and structures. In this review, the latest technological development utilizing the supercritical fluid-based decellularization for regenerative medicine is introduced.

Automated summary

Supercritical fluid-based extraction technologies are increasingly utilized for high purity extract products in food industries, and have been transformed for use in tissue engineering and biomedical applications. Supercritical fluid-based decellularization protocols offer advantages over conventional methods by preserving extracellular matrix components and structures, making them ideal for regenerative medicine applications.