Monocytes promote pyroptosis of endothelial cells during lung ischemia-reperfusion via IL-1R/NF-κB/NLRP3 signaling

Human Lung Cell Pyroptosis Following Traumatic Brain Injury

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NLRP3/ASC-mediated alveolar macrophage pyroptosis enhances HMGB1 secretion in acute lung injury induced by cardiopulmonary bypass

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The selective Nlrp3 inflammasome inhibitor Mcc950 attenuates lung ischemia-reperfusion injury

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Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases

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Donor pulmonary intravascular nonclassical monocytes recruit recipient neutrophils and mediate primary lung allograft dysfunction

(2017) Zhikun Zheng et al.   Science Translational Medicine

Intravascular donor monocytes play a central role in lung transplant ischaemia-reperfusion injury

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Targeting Circulating Leukocytes and Pyroptosis During Ex Vivo Lung Perfusion Improves Lung Preservation

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Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death

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Flow Cytometry Reveals Similarities Between Lung Macrophages in Humans and Mice

(2016) Ankit Bharat et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Roles of Caspases in Necrotic Cell Death

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Role of monocytes and macrophages in regulating immune response following lung transplantation

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Mechanisms of lung ischemia-reperfusion injury

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TLR4-Upregulated IL-1β and IL-1RI Promote Alveolar Macrophage Pyroptosis and Lung Inflammation through an Autocrine Mechanism

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Mechanical removal of dendritic cell–generating non-classical monocytes via ex vivo lung perfusion

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NLRP3 Regulates Neutrophil Functions and Contributes to Hepatic Ischemia-Reperfusion Injury Independently of Inflammasomes

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Gene Set Enrichment Analysis Identifies Key Innate Immune Pathways in Primary Graft Dysfunction After Lung Transplantation

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NLRP3 in myocardial ischaemia-reperfusion injury: inflammasome-dependent or -independent role in different cell types

(2013) M. Takahashi   CARDIOVASCULAR RESEARCH

K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter

(2013) Raúl Muñoz-Planillo et al.   IMMUNITY

CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation

(2013) Frederick J Sheedy et al.   NATURE IMMUNOLOGY

Lung ischemia-reperfusion injury: a molecular and clinical view on a complex pathophysiological process

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A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

In vivo two-photon imaging reveals monocyte-dependent neutrophil extravasation during pulmonary inflammation

(2010) D. Kreisel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cholesterol-dependent cytolysins induce rapid release of mature IL-1β from murine macrophages in a NLRP3 inflammasome and cathepsin B-dependent manner

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CD4+ T lymphocytes mediate acute pulmonary ischemia–reperfusion injury

(2009) Zequan Yang et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY