Novel benzothiazole hybrids targeting EGFR: Design, synthesis, biological evaluation and molecular docking studies

Design, synthesis, and molecular docking of novel 2‐arylbenzothiazole multiangiokinase inhibitors targeting breast cancer

(2020) Heba T. Abdel‐Mohsen et al.   ARCHIV DER PHARMAZIE

Design, synthesis, molecular docking and antiproliferative activity of some novel benzothiazole derivatives targeting EGFR/HER2 and TS

(2020) Khaled R. A. Abdellatif et al.   BIOORGANIC CHEMISTRY

Anticancer Activities of Newly Synthesized Chiral Macrocyclic Heptapeptide Candidates

(2020) Mohamed H. Abo-Ghalia et al.   MOLECULES

Synthesis and anticancer activity of thiourea derivatives bearing a benzodioxole moiety with EGFR inhibitory activity, apoptosis assay and molecular docking study

(2020) Samir Y. Abbas et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Benzothiazoles as potential antiviral agents

(2020) Yahya I. Asiri et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Design, synthesis, biological evaluation, QSAR analysis and molecular modelling of new thiazol-benzimidazoles as EGFR inhibitors

(2020) Aladdin M. Srour et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Pyrazolo-benzothiazole hybrids: Synthesis, anticancer properties and evaluation of antiangiogenic activity using in vitro VEGFR-2 kinase and in vivo transgenic zebrafish model

(2019) Velma Ganga Reddy et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Novel 2-arylbenzothiazole DNA gyrase inhibitors: Synthesis, antimicrobial evaluation, QSAR and molecular docking studies

(2019) Iman A.Y. Ghannam et al.   BIOORGANIC CHEMISTRY

Benzothiazole derivatives as anticancer agents

(2019) Ali Irfan et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Apoptosis: A Target for Anticancer Therapy

(2018) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Expanding the medicinal chemistry synthetic toolbox

(2018) Jonas Boström et al.   NATURE REVIEWS DRUG DISCOVERY

Kinase Inhibitory Activities and Molecular Docking of a Novel Series of Anticancer Pyrazole Derivatives

(2018) Eman Nossier et al.   MOLECULES

An efficient green synthesis of 2-arylbenzothiazole analogues as potent antibacterial and anticancer agents

(2016) Mohit Chhabra et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Current Challenges in Cancer Treatment

(2016) Jon Zugazagoitia et al.   CLINICAL THERAPEUTICS

POM analyses and evaluation of in vitro antimicrobial, antitumor activity of 4H-pyrimido[2,1-b]benzothiazole derivatives

(2016) Pramod K. Sahu et al.   MEDICINAL CHEMISTRY RESEARCH

Synthesis of some novel 4-benzothiazol-2-yl-benzoyl-1H-pyrazoles, and evaluation as antiangiogenic agents

(2015) Eman Ali Abd El-Meguid et al.   RESEARCH ON CHEMICAL INTERMEDIATES

New series of benzothiazole and pyrimido[2,1-b]benzothiazole derivatives: synthesis, antitumor activity, EGFR tyrosine kinase inhibitory activity and molecular modeling studies

(2014) Moustafa T. Gabr et al.   MEDICINAL CHEMISTRY RESEARCH

Targeted molecular therapies against epidermal growth factor receptor: Past experiences and challenges

(2014) D. A. Reardon et al.   NEURO-ONCOLOGY

Drug Resistance in Cancer: An Overview

(2014) Genevieve Housman et al.   Cancers

Synthesis, Anti-Breast Cancer Activity, and Molecular Modeling of Some Benzothiazole and Benzoxazole Derivatives

(2013) Mohamed A. Abdelgawad et al.   ARCHIV DER PHARMAZIE

Tyrosine Kinase Inhibitors: Views of Selectivity, Sensitivity, and Clinical Performance

(2012) Alexander Levitzki   Annual Review of Pharmacology and Toxicology

Synthesis of novel 2-mercapto benzothiazole and 1,2,3-triazole based bis-heterocycles: Their anti-inflammatory and anti-nociceptive activities

(2012) Syed Shafi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Targeting the EGFR signaling pathway in cancer therapy

(2012) Parthasarathy Seshacharyulu et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Medicinal significance of benzothiazole scaffold: an insight view

(2012) Prabodh Chander Sharma et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Design, synthesis and biological evaluation of thiazolidinone derivatives as potential EGFR and HER-2 kinase inhibitors

(2009) Peng-Cheng Lv et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Anti-epidermal growth factor receptor monoclonal antibodies in cancer treatment

(2009) Jaume Capdevila et al.   CANCER TREATMENT REVIEWS

Synthesis, characterization and biological evaluation of some thiourea derivatives bearing benzothiazole moiety as potential antimicrobial and anticancer agents

(2009) Sohail Saeed et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Antidiabetic activity of N-(6-substituted-1,3-benzothiazol-2-yl)benzenesulfonamides

(2008) Hermenegilda Moreno-Díaz et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A History of Cancer Chemotherapy

(2008) Vincent T. DeVita et al.   CANCER RESEARCH

From Single- to Multi-Target Drugs in Cancer Therapy: When Aspecificity Becomes an Advantage

(2008) S. Giordano et al.   CURRENT MEDICINAL CHEMISTRY

Bcl-2 family proteins and cancer

(2008) K W Yip et al.   ONCOGENE