Structural Analysis of Toxin-Neutralizing, Single-Domain Antibodies that Bridge Ricin’s A-B Subunit Interface

Ricin Antibodies’ Neutralizing Capacity against Different Ricin Isoforms and Cultivars

(2021) Maria Lucia Orsini Delgado et al.   Toxins

Intracellular Neutralization of Ricin Toxin by Single-domain Antibodies Targeting the Active Site

(2020) Michael J. Rudolph et al.   JOURNAL OF MOLECULAR BIOLOGY

Passive immunization with an extended half-life monoclonal antibody protects Rhesus macaques against aerosolized ricin toxin

(2020) Chad J. Roy et al.   npj Vaccines

A Humanized Monoclonal Antibody Cocktail to Prevent Pulmonary Ricin Intoxication

(2020) Yinghui Rong et al.   Toxins

Intracellular Transport and Cytotoxicity of the Protein Toxin Ricin

(2019) Natalia Sowa-Rogozińska et al.   Toxins

An intranasally administered monoclonal antibody cocktail abrogates ricin toxin-induced pulmonary tissue damage and inflammation

(2019) Yinghui Rong et al.   Human Vaccines & Immunotherapeutics

Retro-2 protects cells from ricin toxicity by inhibiting ASNA1-mediated ER targeting and insertion of tail-anchored proteins

(2019) David W Morgens et al.   eLife

Early disruption of the alveolar-capillary barrier in a ricin-induced ARDS mouse model: neutrophil-dependent and -independent impairment of junction proteins

(2018) Anita Sapoznikov et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Beyond the Dirty Dozen: A Proposed Methodology for Assessing Future Bioweapon Threats

(2017) Theodore J Cieslak et al.   MILITARY MEDICINE

A Supercluster of Neutralizing Epitopes at the Interface of Ricin’s Enzymatic (RTA) and Binding (RTB) Subunits

(2017) Amanda Poon et al.   Toxins

Treatments for Pulmonary Ricin Intoxication: Current Aspects and Future Prospects

(2017) Yoav Gal et al.   Toxins

Progress and challenges associated with the development of ricin toxin subunit vaccines

(2016) David J. Vance et al.   Expert Review of Vaccines

Structural Analysis of Single Domain Antibodies Bound to a Second Neutralizing Hot Spot on Ricin Toxin's Enzymatic Subunit

(2016) Michael J. Rudolph et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural analysis of nested neutralizing and non-neutralizing B cell epitopes on ricin toxin's enzymatic subunit

(2016) Michael J. Rudolph et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Neutralizing Monoclonal Antibodies against Disparate Epitopes on Ricin Toxin’s Enzymatic Subunit Interfere with Intracellular Toxin Transport

(2016) Anastasiya Yermakova et al.   Scientific Reports

Recent advances in the development of vaccines against ricin

(2016) Robert N. Brey et al.   Human Vaccines & Immunotherapeutics

A Bispecific Antibody Promotes Aggregation of Ricin Toxin on Cell Surfaces and Alters Dynamics of Toxin Internalization and Trafficking

(2016) Cristina Herrera et al.   PLoS One

Safety and immunogenicity of ricin vaccine, RV Ec ™, in a Phase 1 clinical trial

(2015) Phillip R. Pittman et al.   VACCINE

Ricin Trafficking in Cells

(2015) Robert Spooner et al.   Toxins

Diverse Profiles of Ricin-Cell Interactions in the Lung Following Intranasal Exposure to Ricin

(2015) Anita Sapoznikov et al.   Toxins

Clinical and Pathological Findings Associated with Aerosol Exposure of Macaques to Ricin Toxin

(2015) Seth Pincus et al.   Toxins

Characterization and Epitope Mapping of the Polyclonal Antibody Repertoire Elicited by Ricin Holotoxin-Based Vaccination

(2014) Ofer Cohen et al.   Clinical and Vaccine Immunology

Crystal Structures of Ricin Toxin's Enzymatic Subunit (RTA) in Complex with Neutralizing and Non-Neutralizing Single-Chain Antibodies

(2014) Michael J. Rudolph et al.   JOURNAL OF MOLECULAR BIOLOGY

Differential Neutralizing Activities of a Single Domain Camelid Antibody (VHH) Specific for Ricin Toxin’s Binding Subunit (RTB)

(2014) Cristina Herrera et al.   PLoS One

Antibody-Mediated Inhibition of Ricin Toxin Retrograde Transport

(2014) A. Yermakova et al.   mBio

Localization of non-linear neutralizing B cell epitopes on ricin toxin's enzymatic subunit (RTA)

(2013) Joanne M. O’Hara et al.   IMMUNOLOGY LETTERS

Pilot Phase IB Clinical Trial of an Alhydrogel-Adsorbed Recombinant Ricin Vaccine

(2012) Ellen S. Vitetta et al.   Clinical and Vaccine Immunology

Sub-Domains of Ricin’s B Subunit as Targets of Toxin Neutralizing and Non-Neutralizing Monoclonal Antibodies

(2012) Anastasiya Yermakova et al.   PLoS One

Identification of Small Molecules That Suppress Ricin-Induced Stress-Activated Signaling Pathways

(2012) Paul G. Wahome et al.   PLoS One

Resolution of two overlapping neutralizing B cell epitopes within a solvent exposed, immunodominant α-helix in ricin toxin's enzymatic subunit

(2012) David J. Vance et al.   TOXICON

Chemical Structure of Retro-2, a Compound That Protects Cells against Ribosome-Inactivating Proteins

(2012) Jewn Giew Park et al.   Scientific Reports

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Stability and Sugar Recognition Ability of Ricin-like Carbohydrate Binding Domains

(2011) Jianzhuang Yao et al.   BIOCHEMISTRY

Neutralising Antibodies against Ricin Toxin

(2011) Julie Prigent et al.   PLoS One

Protective immunity to ricin toxin conferred by antibodies against the toxin's binding subunit (RTB)

(2011) Anastasiya Yermakova et al.   VACCINE

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Inhibition of Retrograde Transport Protects Mice from Lethal Ricin Challenge

(2010) Bahne Stechmann et al.   CELL

Folding domains within the ricin toxin A subunit as targets of protective antibodies

(2010) Joanne M. O’Hara et al.   VACCINE

Cytosolic chaperones influence the fate of a toxin dislocated from the endoplasmic reticulum

(2008) R. A. Spooner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA