Recent advances in the development of vaccines against ricin

Comparative Adjuvant Effects of Type II Heat-Labile Enterotoxins in Combination with Two Different Candidate Ricin Toxin Vaccine Antigens

(2015) David J. Vance et al.   Clinical and Vaccine Immunology

Thermostable ricin vaccine protects rhesus macaques against aerosolized ricin: Epitope-specific neutralizing antibodies correlate with protection

(2015) Chad J. Roy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Safety and immunogenicity of ricin vaccine, RV Ec ™, in a Phase 1 clinical trial

(2015) Phillip R. Pittman et al.   VACCINE

Clinical and Pathological Findings Associated with Aerosol Exposure of Macaques to Ricin Toxin

(2015) Seth Pincus et al.   Toxins

Chimeric Plantibody Passively Protects Mice against Aerosolized Ricin Challenge

(2014) Erin K. Sully et al.   Clinical and Vaccine Immunology

Crystal Structures of Ricin Toxin's Enzymatic Subunit (RTA) in Complex with Neutralizing and Non-Neutralizing Single-Chain Antibodies

(2014) Michael J. Rudolph et al.   JOURNAL OF MOLECULAR BIOLOGY

Antibody-Mediated Inhibition of Ricin Toxin Retrograde Transport

(2014) A. Yermakova et al.   mBio

Role of Fc in Antibody-Mediated Protection from Ricin Toxin

(2014) Seth. Pincus et al.   Toxins

Comparative Efficacy of Two Leading Candidate Ricin Toxin A Subunit Vaccines in Mice

(2013) Joanne M. O'Hara et al.   Clinical and Vaccine Immunology

Complex Correlates of Protection After Vaccination

(2013) S. A. Plotkin   CLINICAL INFECTIOUS DISEASES

Stabilization of a recombinant ricin toxin A subunit vaccine through lyophilization

(2013) Kimberly J. Hassett et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Localization of non-linear neutralizing B cell epitopes on ricin toxin's enzymatic subunit (RTA)

(2013) Joanne M. O’Hara et al.   IMMUNOLOGY LETTERS

Arginine Residues on the Opposite Side of the Active Site Stimulate the Catalysis of Ribosome Depurination by Ricin A Chain by Interacting with the P-protein Stalk

(2013) Xiao-Ping Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neutralizing monoclonal antibodies against ricin's enzymatic subunit interfere with protein disulfide isomerase-mediated reduction of ricin holotoxin in vitro

(2013) Joanne M. O'Hara et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Antibody to Ricin A Chain Hinders Intracellular Routing of Toxin and Protects Cells Even after Toxin Has Been Internalized

(2013) Kejing Song et al.   PLoS One

Pathology of Lethal and Sublethal Doses of Aerosolized Ricin in Rhesus Macaques

(2013) Manoj Bhaskaran et al.   TOXICOLOGIC PATHOLOGY

Current biodefense vaccine programs and challenges

(2013) Daniel N. Wolfe et al.   Human Vaccines & Immunotherapeutics

Pilot Phase IB Clinical Trial of an Alhydrogel-Adsorbed Recombinant Ricin Vaccine

(2012) Ellen S. Vitetta et al.   Clinical and Vaccine Immunology

Resolution of two overlapping neutralizing B cell epitopes within a solvent exposed, immunodominant α-helix in ricin toxin's enzymatic subunit

(2012) David J. Vance et al.   TOXICON

Structure of RiVax: a recombinant ricin vaccine

(2011) Patricia M. Legler et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Progress in Biological Threat Agent Vaccine Development

(2011) Daniel E. McLain et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Protective Effect of Two Recombinant Ricin Subunit Vaccines in the New Zealand White Rabbit Subjected to a Lethal Aerosolized Ricin Challenge: Survival, Immunological Response, and Histopathological Findings

(2011) Daniel E. McLain et al.   TOXICOLOGICAL SCIENCES

Evaluation of a ricin vaccine candidate (RVEc) for human toxicity using an in vitro vascular leak assay

(2011) Aimee Porter et al.   TOXICON

Intradermal administration of RiVax protects mice from mucosal and systemic ricin intoxication

(2010) Praveena S. Marconescu et al.   VACCINE

Folding domains within the ricin toxin A subunit as targets of protective antibodies

(2010) Joanne M. O’Hara et al.   VACCINE

A Monoclonal Immunoglobulin G Antibody Directed against an Immunodominant Linear Epitope on the Ricin A Chain Confers Systemic and Mucosal Immunity to Ricin

(2009) L. M. Neal et al.   INFECTION AND IMMUNITY

Inflammatory gene expression in response to sub-lethal ricin exposure in Balb/c mice

(2009) Jonathan David et al.   TOXICOLOGY

Vaccines: Correlates of Vaccine‐Induced Immunity

(2008) Stanley A. Plotkin   CLINICAL INFECTIOUS DISEASES