Current Landscape and Future Perspective of Oxazolidinone Scaffolds Containing Antibacterial Drugs
出版年份 2021 全文链接
标题
Current Landscape and Future Perspective of Oxazolidinone Scaffolds Containing Antibacterial Drugs
作者
关键词
-
出版物
JOURNAL OF MEDICINAL CHEMISTRY
Volume 64, Issue 15, Pages 10557-10580
出版商
American Chemical Society (ACS)
发表日期
2021-07-15
DOI
10.1021/acs.jmedchem.1c00480
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Identification of Novel Tricyclic Benzo[1,3]oxazinyloxazolidinones as Potent Antibacterial Agents with Excellent Pharmacokinetic Profiles against Drug-Resistant Pathogens
- (2021) Yongqi Wu et al. JOURNAL OF MEDICINAL CHEMISTRY
- Design, synthesis, and biological evaluation of 3-amino-2-oxazolidinone derivatives as potent quorum-sensing inhibitors of Pseudomonas aeruginosa PAO1
- (2020) Kai Jiang et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- (S)-4-(4-aminobenzyl)-2-oxazolidinone based 2-azetidinones for antimicrobial application and luminescent sensing of divalent metal cations
- (2020) Shyamal Baruah et al. JOURNAL OF HETEROCYCLIC CHEMISTRY
- Discovery of a Conformationally Constrained Oxazolidinone with Improved Safety and Efficacy Profiles for the Treatment of Multidrug-Resistant Tuberculosis
- (2020) Hongyi Zhao et al. JOURNAL OF MEDICINAL CHEMISTRY
- Ultrasound Assisted Synthesis, Characterization and Antimicrobial Evaluation of Novel Oxazolidinone- Biphenyl Chalcone Hybrid Derivatives
- (2019) Naresh Panigrahi et al. Indian Journal of Pharmaceutical Education and Research
- cryoEM-Guided Development of Antibiotics for Drug-Resistant Bacteria
- (2019) Matthew J. Belousoff et al. ChemMedChem
- Activity of tedizolid against gram-positive clinical isolates causing infections in Europe and surrounding areas (2014–2015)
- (2019) Michael A. Pfaller et al. JOURNAL OF CHEMOTHERAPY
- Exploration of the structure–activity relationship and druggability of novel oxazolidinone‐based compounds as Gram‐negative antibacterial agents
- (2019) Shi Ding et al. ARCHIV DER PHARMAZIE
- Variedly connected 1,8-naphthalimide-7-chloroquinoline conjugates: Synthesis, anti-mycobacterial and cytotoxic evaluation
- (2019) Shalini et al. BIOORGANIC CHEMISTRY
- Antibiotics: past, present and future
- (2019) Matthew I Hutchings et al. CURRENT OPINION IN MICROBIOLOGY
- Synthesis and antibacterial evaluation of novel oxazolidinone derivatives containing a piperidinyl moiety
- (2019) Yunlei Hou et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Design, synthesis and biological evaluation of spiropyrimidinetriones oxazolidinone derivatives as antibacterial agents
- (2018) Asher M. Siddiqui et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis and antibacterial activity of oxazolidinone derivatives containing nitro heteroaromatic moiety
- (2018) Boxuan Xu et al. CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
- Design and evaluation of biological activities of 1,3-oxazolidinone derivatives bearing amide, sulfonamide, and thiourea moieties
- (2018) Nurcan Karaman et al. ARCHIV DER PHARMAZIE
- Synthesis, biological evaluations and computational studies of N-(3-(-2-(7-Chloroquinolin-2-yl)vinyl) benzylidene)anilines as fungal biofilm inhibitors
- (2018) Firoz A. Kalam Khan et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Antibiotic resistance of Helicobacter pylori in Chinese children: A multicenter retrospective study over 7 years
- (2017) Lan Li et al. HELICOBACTER
- Structural Basis for Linezolid Binding Site Rearrangement in the Staphylococcus aureus Ribosome
- (2017) Matthew J. Belousoff et al. mBio
- Design, Synthesis, and Antibacterial Evaluation of Oxazolidinones with Fused Heterocyclic C-Ring Substructure
- (2017) Mahesh S. Deshmukh et al. ACS Medicinal Chemistry Letters
- Discovery of Fluorine-Containing Benzoxazinyl-oxazolidinones for the Treatment of Multidrug Resistant Tuberculosis
- (2017) Hongyi Zhao et al. ACS Medicinal Chemistry Letters
- Specialty Grand Challenge In Pediatric Infectious Diseases
- (2017) Philippe Lepage et al. Frontiers in Pediatrics
- Thiazole: A Review on Chemistry, Synthesis and Therapeutic Importance of its Derivatives
- (2016) Mahesh T. Chhabria et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Linezolid: a promising option in the treatment of Gram-positives
- (2016) Abed Zahedi Bialvaei et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Antibiotic resistance patterns of Gram-negative and Gram-positive strains isolated from inpatients with nosocomial infections in a tertiary hospital in Beijing, China from 2011 to 2014
- (2016) Xiaoyan Zhu et al. JOURNAL OF CHEMOTHERAPY
- Synthesis of some novel oxazolidinone-thiazole hybrids as potential antimicrobial, antioxidant and UV mediated DNA damage protecting agents
- (2016) Kamalneet Kaur et al. MEDICINAL CHEMISTRY RESEARCH
- LpxC Inhibitors: Design, Synthesis, and Biological Evaluation of Oxazolidinones as Gram-negative Antibacterial Agents
- (2016) Haruaki Kurasaki et al. ACS Medicinal Chemistry Letters
- To be or not to be exclusive: the sutezolid story
- (2016) Christy Wyskiel Lancet Global Health
- Synthesis and structure–activity relationship studies of novel [6,6,5] tricyclic oxazolidinone derivatives as potential antibacterial agents
- (2015) Tao Xue et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Novel Oxazolidinone Antibacterial Analogues with a Substituted Ligustrazine C-ring Unit
- (2015) Yan Chen et al. Chemical Biology & Drug Design
- The Challenge of Efflux-Mediated Antibiotic Resistance in Gram-Negative Bacteria
- (2015) Xian-Zhi Li et al. CLINICAL MICROBIOLOGY REVIEWS
- Evaluation of tedizolid againstStaphylococcus aureusand enterococci with reduced susceptibility to vancomycin, daptomycin or linezolid
- (2015) Katie E. Barber et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Discovery of a Teraryl Oxazolidinone Compound (S)-N-((3-(3-Fluoro-4-(4-(pyridin-2-yl)-1H-pyrazol-1-yl)phenyl)-2-oxooxazolidin-5-yl)methyl)acetamide Phosphate as a Novel Antimicrobial Agent with Enhanced Safety Profile and Efficacies
- (2015) Tao Yang et al. JOURNAL OF MEDICINAL CHEMISTRY
- Discovery of Novel DNA Gyrase Inhibiting Spiropyrimidinetriones: Benzisoxazole Fusion with N-Linked Oxazolidinone Substituents Leading to a Clinical Candidate (ETX0914)
- (2015) Gregory S. Basarab et al. JOURNAL OF MEDICINAL CHEMISTRY
- Design, Synthesis, and Identification of Silicon Incorporated Oxazolidinone Antibiotics with Improved Brain Exposure
- (2015) B. Seetharamsingh et al. ACS Medicinal Chemistry Letters
- Antibacterial Characterization of Novel Synthetic Thiazole Compounds against Methicillin-Resistant Staphylococcus pseudintermedius
- (2015) Haroon Mohammad et al. PLoS One
- Whatʼs new in the treatment of serious MRSA infection?
- (2014) Natasha E. Holmes et al. CURRENT OPINION IN INFECTIOUS DISEASES
- In Vitro Activity of Novel Oxazolidinone Analogs and 13 Conventional Antimicrobial Agents against Clinical Isolates of Staphylococcus aureus in Beijing, China
- (2014) Hong Lei et al. JAPANESE JOURNAL OF INFECTIOUS DISEASES
- New Potent Antibacterial Oxazolidinone (MRX-I) with an Improved Class Safety Profile
- (2014) Mikhail F. Gordeev et al. JOURNAL OF MEDICINAL CHEMISTRY
- Tedizolid for 6 days versus linezolid for 10 days for acute bacterial skin and skin-structure infections (ESTABLISH-2): a randomised, double-blind, phase 3, non-inferiority trial
- (2014) Gregory J Moran et al. LANCET INFECTIOUS DISEASES
- Synthesis and biological evaluation of novel benzoxazinyl-oxazolidinones as potential antibacterial agents
- (2013) Bin Guo et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- 7-Chloroquinoline-isatin Conjugates: Antimalarial, Antitubercular, and Cytotoxic Evaluation
- (2013) Raghu Raj et al. Chemical Biology & Drug Design
- Antibacterial oxazolidinone analogues having a N-hydroxyacetyl-substituted seven-membered [1,2,5]triazepane or [1,2,5]oxadiazepane C-ring unit
- (2013) Hideyuki Suzuki et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis of some new 2-(3-pyridyl)-4,5-disubstituted thiazoles as potent antimicrobial agents
- (2013) Samir Bondock et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis and antibacterial activities of N-substituted-glycinyl 1H-1,2,3-triazolyl oxazolidinones
- (2013) Oludotun A. Phillips et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Tetramethylpyrazine reduces cellular inflammatory response following permanent focal cerebral ischemia in rats
- (2013) Tsung-Kuei Kao et al. EXPERIMENTAL NEUROLOGY
- Tedizolid Phosphate vs Linezolid for Treatment of Acute Bacterial Skin and Skin Structure Infections
- (2013) Philippe Prokocimer et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Solubility-Driven Optimization of (Pyridin-3-yl) Benzoxazinyl-oxazolidinones Leading to a Promising Antibacterial Agent
- (2013) Bin Guo et al. JOURNAL OF MEDICINAL CHEMISTRY
- Pharmacokinetics of Tedizolid Following Oral Administration: Single and Multiple Dose, Effect of Food, and Comparison of Two Solid Forms of the Prodrug
- (2013) Shawn D. Flanagan et al. PHARMACOTHERAPY
- Potent Oxazolidinone Antibacterials with Heteroaromatic C-Ring Substructure
- (2013) Hideyuki Suzuki et al. ACS Medicinal Chemistry Letters
- Recent development of potent analogues of oxazolidinone antibacterial agents
- (2012) Katarzyna Michalska et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Quorum sensing inhibitors: An overview
- (2012) Vipin Chandra Kalia BIOTECHNOLOGY ADVANCES
- UDP-3-O-(R-3-hydroxymyristoyl)-N-Acetylglucosamine Deacetylase (LpxC) Inhibitors: A New Class of Antibacterial Agents
- (2012) J. Zhang et al. CURRENT MEDICINAL CHEMISTRY
- Design, synthesis of some new (2-aminothiazol-4-yl)methylester derivatives as possible antimicrobial and antitubercular agents
- (2012) Ranjith P. Karuvalam et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Tetramethylpyrazine accelerates the function recovery of traumatic spinal cord in rat model by attenuating inflammation
- (2012) Jian-Zhong Hu et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Vancomycin-resistant enterococcal meningitis in an autologous stem cell transplant recipient cured with linezolid
- (2012) K.L. Frasca et al. Transplant Infectious Disease
- Clinical update on linezolid in the treatment of Gram-positive bacterial infections
- (2012) Kate Gould Infection and Drug Resistance
- Synthesis and in vitro activity of novel 1,2,4-triazolo[4,3-a]pyrimidine oxazolidinone antibacterial agents
- (2011) Manoj K. Khera et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Protective effects of ligustrazine on TNF-α-induced endothelial dysfunction
- (2011) Hong-Jin Wu et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Design, Synthesis, and Structure–Activity Relationship Studies of Highly Potent Novel Benzoxazinyl-Oxazolidinone Antibacterial Agents
- (2011) Qisheng Xin et al. JOURNAL OF MEDICINAL CHEMISTRY
- Structure-Activity Relationships of Diverse Oxazolidinones for Linezolid-Resistant Staphylococcus aureus Strains Possessing the cfr Methyltransferase Gene or Ribosomal Mutations
- (2010) J. B. Locke et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Comparative In Vitro Antimicrobial Activities of Torezolid (TR-700), the Active Moiety of a New Oxazolidinone, Torezolid Phosphate (TR-701), Determination of Tentative Disk Diffusion Interpretive Criteria, and Quality Control Ranges
- (2010) S. D. Brown et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Biomarker-Assisted Dose Selection for Safety and Efficacy in Early Development of PNU-100480 for Tuberculosis
- (2010) Robert S. Wallis et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Syntheses, structures and antibiotic activities of LpxC inhibitors based on the diacetylene scaffold
- (2010) Xiaofei Liang et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Species-Specific and Inhibitor-Dependent Conformations of LpxC: Implications for Antibiotic Design
- (2010) Chul-Jin Lee et al. CHEMISTRY & BIOLOGY
- Synthesis and antimicrobial studies of thiazolotriazinones
- (2010) Mari Sithambaram Karthikeyan EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Pharmacokinetics and Whole‐Blood Bactericidal Activity againstMycobacterium tuberculosisof Single Doses of PNU‐100480 in Healthy Volunteers
- (2010) Robert S. Wallis et al. JOURNAL OF INFECTIOUS DISEASES
- The biofilm matrix
- (2010) Hans-Curt Flemming et al. NATURE REVIEWS MICROBIOLOGY
- Addition of PNU-100480 to First-Line Drugs Shortens the Time Needed to Cure Murine Tuberculosis
- (2009) Kathy N. Williams et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- In Vitro Activity of TR-700, the Active Ingredient of the Antibacterial Prodrug TR-701, a Novel Oxazolidinone Antibacterial Agent
- (2009) R. Schaadt et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Synthesis and Antibacterial Activities of Eperezolid Analogs with Glycinyl Substitutions
- (2009) Xiao-Jun Wang et al. ARCHIV DER PHARMAZIE
- Linezolid: a review of safety and tolerability
- (2009) Donald C. Vinh et al. JOURNAL OF INFECTION
- Synthesis of (−)-PNU-286607 by Asymmetric Cyclization of Alkylidene Barbiturates
- (2009) J. Craig Ruble et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- In Vitro Activities of the Rx-01 Oxazolidinones against Hospital and Community Pathogens
- (2008) L. Lawrence et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- In Vitro Activity of TR-700, the Antibacterial Moiety of the Prodrug TR-701, against Linezolid-Resistant Strains
- (2008) K. J. Shaw et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Effect of tetramethylpyrazine on primary afferent transmission mediated by P2X3 receptor in neuropathic pain states
- (2008) Yun Gao et al. BRAIN RESEARCH BULLETIN
- Organoiodine (III)-mediated synthesis of 3-aryl/heteroaryl-5,7-dimethyl-1,2,4-triazolo[4,3-c]pyrimidines as antibacterial agents
- (2008) Ravi Kumar et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Crystal Structure of the Oxazolidinone Antibiotic Linezolid Bound to the 50S Ribosomal Subunit∥
- (2008) Joseph A. Ippolito et al. JOURNAL OF MEDICINAL CHEMISTRY
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started