Novel Broad-Spectrum Antimicrobial Peptide Derived from Anoplin and Its Activity on Bacterial Pneumonia in Mice

Population genomics of Klebsiella pneumoniae

(2020) Kelly L. Wyres et al.   NATURE REVIEWS MICROBIOLOGY

Enhanced cell selectivity of hybrid peptides with potential antimicrobial activity and immunomodulatory effect

(2020) Xiaokang Miao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Bacterial and fungal co-infection in individuals with coronavirus: A rapid review to support COVID-19 antimicrobial prescribing

(2020) Timothy M Rawson et al.   CLINICAL INFECTIOUS DISEASES

Synthesis and anti-pseudomonal activity of new ß-Ala modified analogues of the antimicrobial peptide anoplin

(2020) Chao Zhong et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

A novel apoA‐I mimetic peptide suppresses atherosclerosis by promoting physiological HDL function in apoE −/− mice

(2020) Sanhu Gou et al.   BRITISH JOURNAL OF PHARMACOLOGY

A New Era of Antibiotics: The Clinical Potential of Antimicrobial Peptides

(2020) Katrina Browne et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ultra-short lipopeptides against gram-positive bacteria while alleviating antimicrobial resistance

(2020) Chao Zhong et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Newly designed antimicrobial peptides with potent bioactivity and enhanced cell selectivity prevent and reverse rifampin resistance in Gram-negative bacteria

(2020) Ningyi Zhu et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Antimicrobial Peptides with High Proteolytic Resistance for Combating Gram-Negative Bacteria

(2019) Jiajun Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens

(2019) Zhanyi Yang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Low cationicity is important for systemic in vivo efficacy of database-derived peptides against drug-resistant Gram-positive pathogens

(2019) Biswajit Mishra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Superbug spreads in European hospitals as resistance to last resort antibiotics grows

(2019) Elisabeth Mahase   BMJ-British Medical Journal

Design and synthesis of new N-terminal fatty acid modified-antimicrobial peptide analogues with potent in vitro biological activity

(2019) Chao Zhong et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A new antibiotic selectively kills Gram-negative pathogens

(2019) Yu Imai et al.   NATURE

The antimicrobial peptide thanatin disrupts the bacterial outer membrane and inactivates the NDM-1 metallo-β-lactamase

(2019) Bo Ma et al.   Nature Communications

Antimicrobial peptides conjugated with fatty acids on the side chain of D-amino acid promises antimicrobial potency against multidrug-resistant bacteria

(2019) Chao Zhong et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

The antimicrobial peptide ZY4 combats multidrug-resistantPseudomonas aeruginosaandAcinetobacter baumanniiinfection

(2019) James Mwangi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Self-assembling diphenylalanine peptide nanotubes selectively eradicate bacterial biofilm infection

(2018) Simon L. Porter et al.   Acta Biomaterialia

Introducing Unnatural Amino Acids-Containing Tripeptides as Antimicrobial and Anticancer Agents

(2018) Alaa F. Nahhas et al.   Journal of Biomedical Nanotechnology

Potent Macromolecule-Sized Poration of Lipid Bilayers by the Macrolittins, A Synthetically Evolved Family of Pore-Forming Peptides

(2018) Sijia Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The burden of community-acquired bacterial pneumonia in the era of antibiotic resistance

(2018) Paula Peyrani et al.   Expert Review of Respiratory Medicine

An overview of antimicrobial peptides and the latest advances in their development

(2017) Josep M Sierra et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Design of novel antimicrobial peptide dimer analogues with enhanced antimicrobial activity in vitro and in vivo by intermolecular triazole bridge strategy

(2017) Beijun Liu et al.   PEPTIDES

Investigating the Interaction of Octapeptin A3 with Model Bacterial Membranes

(2017) Mei-Ling Han et al.   ACS Infectious Diseases

Polycarbonates with Potent and Selective Antimicrobial Activity toward Gram-Positive Bacteria

(2016) Alekhya Nimmagadda et al.   BIOMACROMOLECULES

Medicinal significance of naturally occurring cyclotetrapeptides

(2016) Muna Ali Abdalla   Journal of Natural Medicines

Antimicrobial peptides of invertebrates. Part 2. biological functions and mechanisms of action

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Copper-binding tripeptide motif increases potency of the antimicrobial peptide Anoplin via Reactive Oxygen Species generation

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Characterization of cell selectivity, physiological stability and endotoxin neutralization capabilities of α-helix-based peptide amphiphiles

(2015) Zhi Ma et al.   BIOMATERIALS

Design of novel analogues of short antimicrobial peptide anoplin with improved antimicrobial activity

(2014) Yang Wang et al.   JOURNAL OF PEPTIDE SCIENCE

Antimicrobial activities and membrane-active mechanism of CPF-C1 against multidrug-resistant bacteria, a novel antimicrobial peptide derived from skin secretions of the tetraploid frogXenopus clivii

(2014) Junqiu Xie et al.   JOURNAL OF PEPTIDE SCIENCE

Improving the biological activity of the antimicrobial peptide anoplin by membrane anchoring through a lipophilic amino acid derivative

(2013) Jack C. Slootweg et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthetic analogs of anoplin show improved antimicrobial activities

(2013) Jens K. Munk et al.   JOURNAL OF PEPTIDE SCIENCE

Platforms for antibiotic discovery

(2013) Kim Lewis   NATURE REVIEWS DRUG DISCOVERY

Two Hits Are Better than One: Membrane-Active and DNA Binding-Related Double-Action Mechanism of NK-18, a Novel Antimicrobial Peptide Derived from Mammalian NK-Lysin

(2012) Jiexi Yan et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Structure−Activity Relationships of Polymyxin Antibiotics

(2009) Tony Velkov et al.   JOURNAL OF MEDICINAL CHEMISTRY