Chemical Synthesis of TFF3 Reveals Novel Mechanistic Insights and a Gut-Stable Metabolite

Improving the Gastrointestinal Stability of Linaclotide

(2021) Nayara Braga Emidio et al.   JOURNAL OF MEDICINAL CHEMISTRY

Odyssey of trefoil factors in cancer: Diagnostic and therapeutic implications

(2020) Rahat Jahan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

LINGO family receptors are differentially expressed in the mouse brain and form native multimeric complexes

(2020) Anthony Guillemain et al.   FASEB JOURNAL

Trefoil Factor Family: Unresolved Questions and Clinical Perspectives

(2019) Nayara Braga Emidio et al.   TRENDS IN BIOCHEMICAL SCIENCES

Bioluminescence Resonance Energy Transfer as a Method to Study Protein-Protein Interactions: Application to G Protein Coupled Receptor Biology

(2019) Chayma El Khamlichi et al.   MOLECULES

Different Forms of TFF3 in the Human Saliva: Heterodimerization with IgG Fc Binding Protein (FCGBP)

(2019) Till Houben et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

TFF3 interacts with LINGO2 to regulate EGFR activation for protection against colitis and gastrointestinal helminths

(2019) Nicole Maloney Belle et al.   Nature Communications

Different mode of arrestin-3 binding at the human Y 1 and Y 2 receptor

(2018) Lizzy Wanka et al.   CELLULAR SIGNALLING

Orally active peptides - is there a magic bullet?

(2018) Andreas F. B. Räder et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Modulating bacterial and gut mucosal interactions with engineered biofilm matrix proteins

(2018) Anna M. Duraj-Thatte et al.   Scientific Reports

Trefoil factor 3 isolated from human breast milk downregulates cytokines (IL8 and IL6) and promotes human beta defensin (hBD2 and hBD4) expression in intestinal epithelial cells HT-29

(2017) Girolamo Jose Barrera et al.   Bosnian Journal of Basic Medical Sciences

The tarantula toxin β/δ-TRTX-Pre1a highlights the importance of the S1-S2 voltage-sensor region for sodium channel subtype selectivity

(2017) Joshua S. Wingerd et al.   Scientific Reports

Trefoil factor 3 shows anti-inflammatory effects on activated microglia

(2016) Philipp Arnold et al.   CELL AND TISSUE RESEARCH

ITF promotes migration of intestinal epithelial cells through crosstalk between the ERK and JAK/STAT3 pathways

(2016) Juan Le et al.   Scientific Reports

Neuropeptide Trefoil Factor 3 Reverses Depressive-Like Behaviors by Activation of BDNF-ERK-CREB Signaling in Olfactory Bulbectomized Rats

(2015) Jiali Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Double-peak elution profile of a monoclonal antibody in cation exchange chromatography is caused by histidine-protonation-based charge variants

(2015) Haibin Luo et al.   JOURNAL OF CHROMATOGRAPHY A

Toward Oral Delivery of Biopharmaceuticals: An Assessment of the Gastrointestinal Stability of 17 Peptide Drugs

(2015) Jie Wang et al.   MOLECULAR PHARMACEUTICS

Intestinal trefoil factor activates the PI3K/Akt signaling pathway to protect gastric mucosal epithelium from damage

(2014) ZHAORUI SUN et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Trefoil factors in inflammatory bowel disease

(2014) Luise Aamann   WORLD JOURNAL OF GASTROENTEROLOGY

Chemical synthesis of proteins using peptide hydrazides as thioester surrogates

(2013) Ji-Shen Zheng et al.   Nature Protocols

Trefoil Factor 3 as an Endocrine Neuroprotective Factor from the Liver in Experimental Cerebral Ischemia/Reperfusion Injury

(2013) Shu Q. Liu et al.   PLoS One

A novel, biased-like SDF-1 derivative acts synergistically with starPEG-based heparin hydrogels and improves eEPC migration in vitro

(2012) Lars Baumann et al.   JOURNAL OF CONTROLLED RELEASE

PI3K/Akt Signaling Pathway in the Basolateral Amygdala Mediates the Rapid Antidepressant-like Effects of Trefoil Factor 3

(2012) Hai-Shui Shi et al.   NEUROPSYCHOPHARMACOLOGY

Trefoil Factor Family Peptides in Normal and Diseased Human Pancreas

(2012) Naomi J. Guppy et al.   PANCREAS

Neuropeptide Trefoil factor 3 improves learning and retention of novel object recognition memory in mice

(2011) Hai-Shui Shi et al.   BEHAVIOURAL BRAIN RESEARCH

The Rat IgGFcγBP and Muc2 C-Terminal Domains and TFF3 in Two Intestinal Mucus Layers Bind Together by Covalent Interaction

(2011) Hao Yu et al.   PLoS One

Agonists for the Chemokine Receptor CXCR4

(2011) Marilou Lefrançois et al.   ACS Medicinal Chemistry Letters

Human Intestinal TFF3 Forms Disulfide-Linked Heteromers with the Mucus-Associated FCGBP Protein and Is Released by Hydrogen Sulfide

(2010) Timo K. Albert et al.   JOURNAL OF PROTEOME RESEARCH

A chimeric peptide of intestinal trefoil factor containing cholesteryl ester transfer protein B cell epitope significantly inhibits atherosclerosis in rabbits after oral administration

(2010) Gaofu Qi et al.   PEPTIDES

Phase II, Randomized, Double-Blind, Placebo-Controlled Study of Recombinant Human Intestinal Trefoil Factor Oral Spray for Prevention of Oral Mucositis in Patients With Colorectal Cancer Who Are Receiving Fluorouracil-Based Chemotherapy

(2009) Douglas E. Peterson et al.   JOURNAL OF CLINICAL ONCOLOGY

Stability and Biological Activity of Human Intestinal Trefoil Factor Produced by Pichia pastoris

(2008) Xi Peng et al.   PROTEIN AND PEPTIDE LETTERS

Are trefoil factors oncogenic?

(2007) Jo K. Perry et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM