Distinct Biological Activities of Isomers from Different Families of Branched Fatty Acid Esters of Hydroxy Fatty Acids (FAHFAs)

Effect of 9 - PAHSA on cognitive dysfunction in diabetic mice and its possible mechanism

(2020) Xiao-Hong Wen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Long-term high intake of 9-PAHPA or 9-OAHPA increases basal metabolism and insulin sensitivity but disrupts liver homeostasis in healthy mice

(2020) Melha Benlebna et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

FAHFA footprint in the visceral fat of mice across their lifespan

(2020) Quan-Fei Zhu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Comprehensive analysis of PPARγ agonist activities of stereo-, regio-, and enantio-isomers of hydroxyoctadecadienoic acids

(2020) Aya Umeno et al.   BIOSCIENCE REPORTS

Triacylglycerol‐Rich Oils of Marine Origin are Optimal Nutrients for Induction of Polyunsaturated Docosahexaenoic Acid Ester of Hydroxy Linoleic Acid (13‐DHAHLA) with Anti‐Inflammatory Properties in Mice

(2020) Veronika Paluchova et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Understanding FAHFAs: From structure to metabolic regulation

(2020) Kristyna Brejchova et al.   PROGRESS IN LIPID RESEARCH

FAHFAs Regulate the Proliferation of C2C12 Myoblasts and Induce a Shift toward a More Oxidative Phenotype in Mouse Skeletal Muscle

(2020) Melha Benlebna et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

High Glucose Concentration Impairs 5-PAHSA Activity by Inhibiting AMP-Activated Protein Kinase Activation and Promoting Nuclear Factor-Kappa-B-Mediated Inflammation

(2019) Yan-Mei Wang et al.   Frontiers in Pharmacology

Synthesis of chemically edited derivatives of the endogenous regulator of inflammation 9-PAHSA

(2019) Huijing Wang et al.   JOURNAL OF ANTIBIOTICS

Analysis of Fatty Acid Esters of Hydroxyl Fatty Acid in Selected Plant Food

(2019) Ana-Marija Liberati-Čizmek et al.   PLANT FOODS FOR HUMAN NUTRITION

Age at Diagnosis of Type 2 Diabetes Mellitus and Associations With Cardiovascular and Mortality Risks

(2019) Naveed Sattar et al.   CIRCULATION

Linoleic acid esters of hydroxy linoleic acids are anti-inflammatory lipids found in plants and mammals

(2019) Matthew J. Kolar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

WITHDRAWN: Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: results from the International Diabetes Federation Diabetes Atlas, 9th edition

(2019) Pouya Saeedi et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

PAHSAs attenuate immune responses and promote β cell survival in autoimmune diabetic mice

(2019) Ismail Syed et al.   JOURNAL OF CLINICAL INVESTIGATION

PAHSAs enhance hepatic and systemic insulin sensitivity through direct and indirect mechanisms

(2019) Peng Zhou et al.   JOURNAL OF CLINICAL INVESTIGATION

Identification of lipophilic ligands of Siglec5 and -14 that modulate innate immune responses

(2019) Rie Suematsu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipokine 5-PAHSA Is Regulated by Adipose Triglyceride Lipase and Primes Adipocytes for De Novo Lipogenesis in Mice

(2019) Veronika Paluchova et al.   DIABETES

Alpha-linolenic acid enhances the phagocytic and secretory functions of alternatively activated macrophages in part via changes to the oxylipin profile

(2019) Samantha D. Pauls et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Faster Protocol for Endogenous Fatty Acid Esters of Hydroxy Fatty Acid (FAHFA) Measurements

(2018) Matthew J. Kolar et al.   ANALYTICAL CHEMISTRY

Levels of palmitic acid ester of hydroxystearic acid (PAHSA) are reduced in the breast milk of obese mothers

(2018) Marie Brezinova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Palmitic Acid Hydroxystearic Acids Activate GPR40, Which Is Involved in Their Beneficial Effects on Glucose Homeostasis

(2018) Ismail Syed et al.   Cell Metabolism

A UPLC/MS/MS method for comprehensive profiling and quantification of fatty acid esters of hydroxy fatty acids in white adipose tissue

(2018) Ting Hu et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Comprehensive Screening and Identification of Fatty Acid Esters of Hydroxy Fatty Acids in Plant Tissues by Chemical Isotope Labeling-Assisted Liquid Chromatography–Mass Spectrometry

(2018) Quan-Fei Zhu et al.   ANALYTICAL CHEMISTRY

Microfluidic-enabled quantitative measurements of insulin release dynamics from single islets of Langerhans in response to 5-palmitic acid hydroxy stearic acid

(2018) Basel Bandak et al.   LAB ON A CHIP

Adipose tissue dysfunction is associated with low levels of the novel Palmitic Acid Hydroxystearic Acids

(2018) Ann Hammarstedt et al.   Scientific Reports

Stereochemistry of Endogenous Palmitic Acid Ester of 9-Hydroxystearic Acid and Relevance of Absolute Configuration to Regulation

(2017) Andrew T. Nelson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Absence of Carbohydrate Response Element Binding Protein in Adipocytes Causes Systemic Insulin Resistance and Impairs Glucose Transport

(2017) Archana Vijayakumar et al.   Cell Reports

Is There a Role for Bioactive Lipids in the Pathobiology of Diabetes Mellitus?

(2017) Undurti N. Das   Frontiers in Endocrinology

Branched Fatty Acid Esters of Hydroxy Fatty Acids Are Preferred Substrates of the MODY8 Protein Carboxyl Ester Lipase

(2016) Matthew J. Kolar et al.   BIOCHEMISTRY

Docosahexaenoic Acid–Derived Fatty Acid Esters of Hydroxy Fatty Acids (FAHFAs) With Anti-inflammatory Properties

(2016) Ondrej Kuda et al.   DIABETES

Branched Fatty Acid Esters of Hydroxy Fatty Acids (FAHFAs) Protect against Colitis by Regulating Gut Innate and Adaptive Immune Responses

(2016) Jennifer Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A LC-MS–based workflow for measurement of branched fatty acid esters of hydroxy fatty acids

(2016) Tejia Zhang et al.   Nature Protocols

Discovery of a Class of Endogenous Mammalian Lipids with Anti-Diabetic and Anti-inflammatory Effects

(2014) Mark M. Yore et al.   CELL

RBP4 Activates Antigen-Presenting Cells, Leading to Adipose Tissue Inflammation and Systemic Insulin Resistance

(2014) Pedro M. Moraes-Vieira et al.   Cell Metabolism

Efficacy of GLP-1 Receptor Agonists and DPP-4 Inhibitors: Meta-Analysis and Systematic Review

(2012) Vanita R. Aroda et al.   CLINICAL THERAPEUTICS

The membrane interaction of drugs as one of mechanisms for their enantioselective effects

(2012) Hironori Tsuchiya et al.   MEDICAL HYPOTHESES

Retinol-Binding Protein 4 Inhibits Insulin Signaling in Adipocytes by Inducing Proinflammatory Cytokines in Macrophages through a c-Jun N-Terminal Kinase- and Toll-Like Receptor 4-Dependent and Retinol-Independent Mechanism

(2012) J. Norseen et al.   MOLECULAR AND CELLULAR BIOLOGY

Inflammatory links between obesity and metabolic disease

(2011) Carey N. Lumeng et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophages, Inflammation, and Insulin Resistance

(2010) Jerrold M. Olefsky et al.   Annual Review of Physiology

Protein Farnesylation-Dependent Raf/Extracellular Signal-Related Kinase Signaling Links to Cytoskeletal Remodeling to Facilitate Glucose-Induced Insulin Secretion in Pancreatic  -Cells

(2010) A. Kowluru et al.   DIABETES

15-Hydroxyeicosatetraenoic Acid Is a Preferential Peroxisome Proliferator-Activated Receptor  /  Agonist

(2009) S. Naruhn et al.   MOLECULAR PHARMACOLOGY

Bioactive lipids in metabolic syndrome

(2008) Koji Nagao et al.   PROGRESS IN LIPID RESEARCH