A HIF1α-GPD1 feedforward loop inhibits the progression of renal clear cell carcinoma via mitochondrial function and lipid metabolism

GPD1 enhances the anti-cancer effects of metformin by synergistically increasing total cellular glycerol-3-phosphate

(2020) Jianjiang Xie et al.   CANCER RESEARCH

LRRC19—A Bridge between Selenium Adjuvant Therapy and Renal Clear Cell Carcinoma: A Study Based on Datamining

(2020) Yitong Zhang et al.   Genes

Aberrant Expression of Citrate Synthase is Linked to Disease Progression and Clinical Outcome in Prostate Cancer

(2020) Zhiduan Cai et al.   Cancer Management and Research

Role of Mitochondrial Glycerol-3-Phosphate Dehydrogenase in Metabolic Adaptations of Prostate Cancer

(2020) Alena Pecinová et al.   Cells

HIF-1α and HIF-2α differently regulate tumour development and inflammation of clear cell renal cell carcinoma in mice

(2020) Rouven Hoefflin et al.   Nature Communications

Loss of KCNJ15 expression promotes malignant phenotypes and correlates with poor prognosis in renal carcinoma

(2019) Yang Liu et al.   Cancer Management and Research

HIF1α Suppresses Tumor Cell Proliferation through Inhibition of Aspartate Biosynthesis

(2019) Florinda Meléndez-Rodríguez et al.   Cell Reports

Decreased expression of SLC16A12 mRNA predicts poor prognosis of patients with clear cell renal cell carcinoma

(2019) Jie Mei et al.   MEDICINE

Metformin Targets Mitochondrial Glycerophosphate Dehydrogenase to Control Rate of Oxidative Phosphorylation and Growth of Thyroid CancerIn VitroandIn Vivo

(2018) Shilpa Thakur et al.   CLINICAL CANCER RESEARCH

Metabolic Pathways in Kidney Cancer: Current Therapies and Future Directions

(2018) W. Kimryn Rathmell et al.   JOURNAL OF CLINICAL ONCOLOGY

HIF drives lipid deposition and cancer in ccRCC via repression of fatty acid metabolism

(2017) Weinan Du et al.   Nature Communications

An Integrated Metabolic Atlas of Clear Cell Renal Cell Carcinoma

(2016) A. Ari Hakimi et al.   CANCER CELL

Hypoxia, Hypoxia-inducible Transcription Factors, and Renal Cancer

(2016) Johannes Schödel et al.   EUROPEAN UROLOGY

The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs—Part A: Renal, Penile, and Testicular Tumours

(2016) Holger Moch et al.   EUROPEAN UROLOGY

Lipidomic Signatures and Associated Transcriptomic Profiles of Clear Cell Renal Cell Carcinoma

(2016) Kosuke Saito et al.   Scientific Reports

Functional characterization of BC039389-GATM and KLK4-KRSP1 chimeric read-through transcripts which are up-regulated in renal cell cancer

(2015) Dorothee Pflueger et al.   BMC GENOMICS

HIF2 -Dependent Lipid Storage Promotes Endoplasmic Reticulum Homeostasis in Clear-Cell Renal Cell Carcinoma

(2015) B. Qiu et al.   Cancer Discovery

Regularization Paths for Cox's Proportional Hazards Model via Coordinate Descent

(2015) Noah Simon et al.   Journal of Statistical Software

Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase

(2014) Anila K. Madiraju et al.   NATURE

Transient Infantile Hypertriglyceridemia, Fatty Liver, and Hepatic Fibrosis Caused by Mutated GPD1, Encoding Glycerol-3-Phosphate Dehydrogenase 1

(2012) Lina Basel-Vanagaite et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The function and the role of the mitochondrial glycerol-3-phosphate dehydrogenase in mammalian tissues

(2012) Tomáš Mráček et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The Specificity of Urinary Aquaporin 1 and Perilipin 2 to Screen for Renal Cell Carcinoma

(2012) Jeremiah J. Morrissey et al.   JOURNAL OF UROLOGY

Genetic and Functional Studies Implicate HIF1  as a 14q Kidney Cancer Suppressor Gene

(2011) C. Shen et al.   Cancer Discovery