Genome-wide Association Study of Estradiol Levels and the Causal Effect of Estradiol on Bone Mineral Density

Using human genetics to understand the disease impacts of testosterone in men and women

(2020) Katherine S Ruth et al.   NATURE MEDICINE

Prevention and therapy of COVID-19 via exogenous estrogen treatment for both male and female patients

(2020) Zsuzsanna Suba   JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES

Genetic association study of eight steroid hormones and implications for sexual dimorphism of coronary artery disease

(2019) Janne Pott et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Genetic Determinants of Circulating Estrogen Levels and Evidence of a Causal Effect of Estradiol on Bone Density in Men

(2018) Anna L Eriksson et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Causal associations between risk factors and common diseases inferred from GWAS summary data

(2018) Zhihong Zhu et al.   Nature Communications

The MR-Base platform supports systematic causal inference across the human phenome

(2018) Gibran Hemani et al.   eLife

Evidence of a Causal Effect of Estradiol on Fracture Risk in Men

(2018) Maria Nethander et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Interpreting findings from Mendelian randomization using the MR-Egger method

(2017) Stephen Burgess et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Misconceptions on the use of MR-Egger regression and the evaluation of the InSIDE assumption

(2017) Jack Bowden   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Genetic prediction of male pattern baldness

(2017) Saskia P. Hagenaars et al.   PLoS Genetics

Minichromosome maintenance complex component 8 mutations cause primary ovarian insufficiency

(2016) Xiaoyun Dou et al.   FERTILITY AND STERILITY

Response to Hartwig and Davies

(2016) Jack Bowden et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

The Genotype-Tissue Expression (GTEx) Project

(2015) Latarsha J. Carithers et al.   BIOPRESERVATION AND BIOBANKING

Glucuronidation of estrone and 16α-hydroxyestrone by human UGT enzymes: The key roles of UGT1A10 and UGT2B7

(2015) Roope A. Kallionpää et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

The UK10K project identifies rare variants in health and disease

(2015)   NATURE

MCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complex

(2015) Kyung Yong Lee et al.   Nature Communications

The Genotype-Tissue Expression (GTEx) Project

(2015) Latarsha J. Carithers et al.   Biopreservation and Biobanking

Estimating Genome-Wide Significance for Whole-Genome Sequencing Studies

(2014) ChangJiang Xu et al.   GENETIC EPIDEMIOLOGY

Exome sequencing reveals MCM8 mutation underlies ovarian failure and chromosomal instability

(2014) Saleh AlAsiri et al.   JOURNAL OF CLINICAL INVESTIGATION

Mediator of ERBB2-driven Cell Motility (MEMO) Promotes Extranuclear Estrogen Receptor Signaling Involving the Growth Factor Receptors IGF1R and ERBB2

(2013) Kai Jiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-wide association study of sex hormones, gonadotropins and sex hormone–binding protein in Chinese men

(2013) Zhuo Chen et al.   JOURNAL OF MEDICAL GENETICS

The structural biology of oestrogen metabolism

(2013) Mark P. Thomas et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

TSPYL5 SNPs: Association with Plasma Estradiol Concentrations and Aromatase Expression

(2013) Mohan Liu et al.   MOLECULAR ENDOCRINOLOGY

The role of estrogen and androgen receptors in bone health and disease

(2013) Stavros C. Manolagas et al.   Nature Reviews Endocrinology

Credible Mendelian Randomization Studies: Approaches for Evaluating the Instrumental Variable Assumptions

(2012) M. M. Glymour et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

1000 Genomes-based imputation identifies novel and refined associations for the Wellcome Trust Case Control Consortium phase 1 Data

(2012) Jie Huang et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

(2012) Karol Estrada et al.   NATURE GENETICS

Physiology of the female reproductive axis

(2012) G. Wright Bates et al.   PERIODONTOLOGY 2000

Genome-Wide Association Study of Circulating Estradiol, Testosterone, and Sex Hormone-Binding Globulin in Postmenopausal Women

(2012) Jennifer Prescott et al.   PLoS One

A Genome-Wide Association Meta-Analysis of Circulating Sex Hormone–Binding Globulin Reveals Multiple Loci Implicated in Sex Steroid Hormone Regulation

(2012) Andrea D. Coviello et al.   PLoS Genetics

Regulation of steroid hormone receptor function by the 52-kDa FK506-binding protein (FKBP52)

(2011) Jeffrey C Sivils et al.   CURRENT OPINION IN PHARMACOLOGY

Interaction between oral estrogen plus progestogen therapy and ABO blood groups on coagulation activation in postmenopausal women

(2011) Daniela Amorim Melgaço Guimarães et al.   MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

(2011) L. D. Ward et al.   NUCLEIC ACIDS RESEARCH

Low testosterone and sex hormone-binding globulin levels and high estradiol levels are independent predictors of type 2 diabetes in men

(2010) Torkel Vikan et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Fkbp52 Regulates Androgen Receptor Transactivation Activity and Male Urethra Morphogenesis

(2010) Hanying Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Kinetic Analysis of the Three-step Steroid Aromatase Reaction of Human Cytochrome P450 19A1

(2010) Christal D. Sohl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quantitative Evaluation of the Expression and Activity of Five Major Sulfotransferases (SULTs) in Human Tissues: The SULT "Pie"

(2009) Z. Riches et al.   DRUG METABOLISM AND DISPOSITION

Identification of UDP Glycosyltransferase 3A1 as a UDPN-Acetylglucosaminyltransferase

(2008) Peter I. Mackenzie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY