标题
TGF‐β signaling: A recap of SMAD‐independent and SMAD‐dependent pathways
作者
关键词
-
出版物
JOURNAL OF CELLULAR PHYSIOLOGY
Volume -, Issue -, Pages -
出版商
Wiley
发表日期
2021-07-19
DOI
10.1002/jcp.30529
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- TGF-β orchestrates fibrogenic and developmental EMTs via the RAS effector RREB1
- (2020) Jie Su et al. NATURE
- TGF-β Signaling
- (2020) Kalliopi Tzavlaki et al. Biomolecules
- Long noncoding RNA H19X is a key mediator of TGF-β–driven fibrosis
- (2020) Elena Pachera et al. JOURNAL OF CLINICAL INVESTIGATION
- RAC1B Regulation of TGFB1 Reveals an Unexpected Role of Autocrine TGFβ1 in the Suppression of Cell Motility
- (2020) Hendrik Ungefroren et al. Cancers
- RAC1B: A Rho GTPase with Versatile Functions in Malignant Transformation and Tumor Progression
- (2019) Catharina Melzer et al. Cells
- Specificity, versatility, and control of TGF-β family signaling
- (2019) Rik Derynck et al. Science Signaling
- JNK-Dependent cJun Phosphorylation Mitigates TGFβ- and EGF-Induced Pre-Malignant Breast Cancer Cell Invasion by Suppressing AP-1-Mediated Transcriptional Responses
- (2019) Anders Sundqvist et al. Cells
- Central role of dysregulation of TGF-β/Smad in CKD progression and potential targets of its treatment
- (2018) Lin Chen et al. BIOMEDICINE & PHARMACOTHERAPY
- New insights into TGF-β/Smad signaling in tissue fibrosis
- (2018) He-He Hu et al. CHEMICO-BIOLOGICAL INTERACTIONS
- TGF-β Mediates Renal Fibrosis via the Smad3-Erbb4-IR Long Noncoding RNA Axis
- (2018) Min Feng et al. MOLECULAR THERAPY
- TGF-β receptors: In and beyond TGF-β signaling
- (2018) Alexandra Vander Ark et al. CELLULAR SIGNALLING
- Long noncoding RNA lnc-TSI inhibits renal fibrogenesis by negatively regulating the TGF-β/Smad3 pathway
- (2018) Peng Wang et al. Science Translational Medicine
- Eukaryotic Initiation Factor 4E (eIF4E) sequestration mediates 4E-BP1 response to rapamycin
- (2018) Asiya Batool et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Reappraisal to the study of 4E-BP1 as an mTOR substrate – A normative critique
- (2017) Asiya Batool et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- JUNB governs a feed-forward network of TGFβ signaling that aggravates breast cancer invasion
- (2017) Anders Sundqvist et al. NUCLEIC ACIDS RESEARCH
- TGF-β Signaling in Cancer
- (2016) Viqar Syed JOURNAL OF CELLULAR BIOCHEMISTRY
- TGF-β: the master regulator of fibrosis
- (2016) Xiao-ming Meng et al. Nature Reviews Nephrology
- mTORC1 and mTORC2 in cancer and the tumor microenvironment
- (2016) L C Kim et al. ONCOGENE
- TGF-β Signaling from Receptors to Smads
- (2016) Akiko Hata et al. Cold Spring Harbor Perspectives in Biology
- Regulation of TGF-β Family Signaling by Inhibitory Smads
- (2016) Keiji Miyazawa et al. Cold Spring Harbor Perspectives in Biology
- Regulation of the Bioavailability of TGF-β and TGF-β-Related Proteins
- (2016) Ian B. Robertson et al. Cold Spring Harbor Perspectives in Biology
- Smad7 Protein Interacts with Receptor-regulated Smads (R-Smads) to Inhibit Transforming Growth Factor-β (TGF-β)/Smad Signaling
- (2015) Xiaohua Yan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- ShcA Protects against Epithelial–Mesenchymal Transition through Compartmentalized Inhibition of TGF-β-Induced Smad Activation
- (2015) Baby Periyanayaki Muthusamy et al. PLOS BIOLOGY
- Loss of SMAD4 Alters BMP Signaling to Promote Colorectal Cancer Cell Metastasis via Activation of Rho and ROCK
- (2014) Philip W. Voorneveld et al. GASTROENTEROLOGY
- TGF- : Duality of Function Between Tumor Prevention and Carcinogenesis
- (2014) D. R. Principe et al. JNCI-Journal of the National Cancer Institute
- Molecular mechanisms of epithelial–mesenchymal transition
- (2014) Samy Lamouille et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- TRAF6 Stimulates the Tumor-Promoting Effects of TGF Type I Receptor Through Polyubiquitination and Activation of Presenilin 1
- (2014) S. K. Gudey et al. Science Signaling
- Smad9 is a new type of transcriptional regulator in bone morphogenetic protein signaling
- (2014) S. Tsukamoto et al. Scientific Reports
- Effects of TGFbeta2 on Wild-Type and Tgfbr3 Knockout Mouse Fetal Testis1
- (2013) Mai A. Sarraj et al. BIOLOGY OF REPRODUCTION
- MicroRNA-216a/217-induced epithelial-mesenchymal transition targets PTEN and SMAD7 to promote drug resistance and recurrence of liver cancer
- (2013) Hongping Xia et al. HEPATOLOGY
- Transforming Growth Factor-β (TGF-β)-mediated Connective Tissue Growth Factor (CTGF) Expression in Hepatic Stellate Cells Requires Stat3 Signaling Activation
- (2013) Yan Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- S6K1 Negatively Regulates TAK1 Activity in the Toll-Like Receptor Signaling Pathway
- (2013) S. Y. Kim et al. MOLECULAR AND CELLULAR BIOLOGY
- TRAF4 Promotes TGF-β Receptor Signaling and Drives Breast Cancer Metastasis
- (2013) Long Zhang et al. MOLECULAR CELL
- Smad6 inhibits non-canonical TGF-β1 signalling by recruiting the deubiquitinase A20 to TRAF6
- (2013) Su Myung Jung et al. Nature Communications
- The TGF -induced phosphorylation and activation of p38 mitogen-activated protein kinase is mediated by MAP3K4 and MAP3K10 but not TAK1
- (2013) G. P. Sapkota Open Biology
- JAK-2 as a novel mediator of the profibrotic effects of transforming growth factor β in systemic sclerosis
- (2012) Clara Dees et al. ARTHRITIS AND RHEUMATISM
- TGF-β signalling and its role in cancer progression and metastasis
- (2012) Yvette Drabsch et al. CANCER AND METASTASIS REVIEWS
- BMP4 Signaling Acts via Dual-Specificity Phosphatase 9 to Control ERK Activity in Mouse Embryonic Stem Cells
- (2012) Zhongwei Li et al. Cell Stem Cell
- O-GlcNAcylation of TAB1 modulates TAK1-mediated cytokine release
- (2012) Shalini Pathak et al. EMBO JOURNAL
- Dynamics of TGF-β/Smad signaling
- (2012) Zhike Zi et al. FEBS LETTERS
- TGF- -induced activation of mTOR complex 2 drives epithelial-mesenchymal transition and cell invasion
- (2012) S. Lamouille et al. JOURNAL OF CELL SCIENCE
- USP4 is regulated by AKT phosphorylation and directly deubiquitylates TGF-β type I receptor
- (2012) Long Zhang et al. NATURE CELL BIOLOGY
- c-Abl promotes osteoblast expansion by differentially regulating canonical and non-canonical BMP pathways and p16INK4a expression
- (2012) Hui-Yi Kua et al. NATURE CELL BIOLOGY
- Specific interactions between Smad proteins and AP-1 components determine TGFβ-induced breast cancer cell invasion
- (2012) A Sundqvist et al. ONCOGENE
- TGFβ-Stimulated MicroRNA-21 Utilizes PTEN to Orchestrate AKT/mTORC1 Signaling for Mesangial Cell Hypertrophy and Matrix Expansion
- (2012) Nirmalya Dey et al. PLoS One
- Induction of epithelial–mesenchymal transition by transforming growth factor β
- (2012) Aristidis Moustakas et al. SEMINARS IN CANCER BIOLOGY
- Akt/PKB-Mediated Phosphorylation of Twist1 Promotes Tumor Metastasis via Mediating Cross-Talk between PI3K/Akt and TGF-β Signaling Axes
- (2012) Gongda Xue et al. Cancer Discovery
- Deconstructing the mechanisms and consequences of TGF-β-induced EMT during cancer progression
- (2011) Michael K. Wendt et al. CELL AND TISSUE RESEARCH
- TGFβ-induced Early Activation of the Small GTPase RhoA is Smad2/3-independent and Involves Src and the Guanine Nucleotide Exchange Factor Vav2
- (2011) Elsa Papadimitriou et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- SNX25 regulates TGF-β signaling by enhancing the receptor degradation
- (2011) Xinbao Hao et al. CELLULAR SIGNALLING
- Switching TGFβ from a tumor suppressor to a tumor promoter
- (2011) Gareth J Inman CURRENT OPINION IN GENETICS & DEVELOPMENT
- Metastatic function of BMP-2 in gastric cancer cells: The role of PI3K/AKT, MAPK, the NF-κB pathway, and MMP-9 expression
- (2011) Myoung Hee Kang et al. EXPERIMENTAL CELL RESEARCH
- Polyubiquitination of Transforming Growth Factor β (TGFβ)-associated Kinase 1 Mediates Nuclear Factor-κB Activation in Response to Different Inflammatory Stimuli
- (2011) Anahita Hamidi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Lung Tumor-associated Osteoblast-derived Bone Morphogenetic Protein-2 Increased Epithelial-to-Mesenchymal Transition of Cancer by Runx2/Snail Signaling Pathway
- (2011) Ya-Ling Hsu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Disruption of Smad4 impairs TGF-β/Smad3 and Smad7 transcriptional regulation during renal inflammation and fibrosis in vivo and in vitro
- (2011) Xiao-Ming Meng et al. KIDNEY INTERNATIONAL
- TSC-22 Promotes Transforming Growth Factor -Mediated Cardiac Myofibroblast Differentiation by Antagonizing Smad7 Activity
- (2011) X. Yan et al. MOLECULAR AND CELLULAR BIOLOGY
- Identification of an mRNP Complex Regulating Tumorigenesis at the Translational Elongation Step
- (2011) George S. Hussey et al. MOLECULAR CELL
- Differential regulation of the two RhoA-specific GEF isoforms Net1/Net1A by TGF-β and miR-24: role in epithelial-to-mesenchymal transition
- (2011) E Papadimitriou et al. ONCOGENE
- Evolution of the TGF-β Signaling Pathway and Its Potential Role in the Ctenophore, Mnemiopsis leidyi
- (2011) Kevin Pang et al. PLoS One
- TRAF6 ubiquitinates TGFβ type I receptor to promote its cleavage and nuclear translocation in cancer
- (2011) Yabing Mu et al. Nature Communications
- PI3K, Erk Signaling in BMP7-Induced Epithelial-Mesenchymal Transition (EMT) of PC-3 Prostate Cancer Cells in 2- and 3-Dimensional Cultures
- (2011) Minyoung Lim et al. Hormones & Cancer
- Regulation of TGF-β signalling by protein phosphatases
- (2010) Ting Liu et al. BIOCHEMICAL JOURNAL
- Transforming growth factor-β and the hallmarks of cancer
- (2010) Maozhen Tian et al. CELLULAR SIGNALLING
- Dorsomorphin and LDN-193189 inhibit BMP-mediated Smad, p38 and Akt signalling in C2C12 cells
- (2010) J.H. Boergermann et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- TGF-β1 Protects against Mesangial Cell Apoptosis via Induction of Autophagy
- (2010) Yan Ding et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- T RI/Alk5-independent T RII signaling to ERK1/2 in human skin cells according to distinct levels of T RII expression
- (2010) B. Bandyopadhyay et al. JOURNAL OF CELL SCIENCE
- The emerging mechanisms of isoform-specific PI3K signalling
- (2010) Bart Vanhaesebroeck et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Fetal Testis Dysgenesis and Compromised Leydig Cell Function in Tgfbr3 (Betaglycan) Knockout Mice1
- (2009) Mai A. Sarraj et al. BIOLOGY OF REPRODUCTION
- Regulation of Cell Proliferation and Migration by TAK1 via Transcriptional Control of von Hippel-Lindau Tumor Suppressor
- (2009) Siew Hwey Tan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- BMP-4 Induction of Arrest and Differentiation of Osteoblast-Like Cells via p21CIP1and p27KIP1Regulation
- (2009) Shun-Fu Chang et al. MOLECULAR ENDOCRINOLOGY
- TGF-β activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN
- (2009) Mitsuo Kato et al. NATURE CELL BIOLOGY
- The E3 Ligase TRAF6 Regulates Akt Ubiquitination and Activation
- (2009) W.-L. Yang et al. SCIENCE
- BMP-2 signaling in ovarian cancer and its association with poor prognosis
- (2009) Cécile Le Page et al. Journal of Ovarian Research
- Grb2 binding to Tyr284 in TβR-II is essential for mammary tumor growth and metastasis stimulated by TGF-β
- (2008) Amy J. Galliher-Beckley et al. CARCINOGENESIS
- Phospho-control of TGF-β superfamily signaling
- (2008) Katharine H Wrighton et al. CELL RESEARCH
- Roles of TGFβ in metastasis
- (2008) David Padua et al. CELL RESEARCH
- Non-Smad pathways in TGF-β signaling
- (2008) Ying E Zhang CELL RESEARCH
- Two highly related regulatory subunits of PP2A exert opposite effects on TGF- /Activin/Nodal signalling
- (2008) J. Batut et al. DEVELOPMENT
- TGFβ-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGFβ switch
- (2008) Irwin M Liu et al. EMBO JOURNAL
- TGF-β coordinately activates TAK1/MEK/AKT/NFkB and SMAD pathways to promote osteoclast survival
- (2008) Anne Gingery et al. EXPERIMENTAL CELL RESEARCH
- Axin and GSK3- control Smad3 protein stability and modulate TGF- signaling
- (2008) X. Guo et al. GENES & DEVELOPMENT
- The role of proteases in transforming growth factor-β activation
- (2008) G JENKINS INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- TGFβ induces SIK to negatively regulate type I receptor kinase signaling
- (2008) Marcin Kowanetz et al. JOURNAL OF CELL BIOLOGY
- BMP2 induction of actin cytoskeleton reorganization and cell migration requires PI3-kinase and Cdc42 activity
- (2008) C. Gamell et al. JOURNAL OF CELL SCIENCE
- Signaling through ShcA Is Required for Transforming Growth Factor - and Neu/ErbB-2-Induced Breast Cancer Cell Motility and Invasion
- (2008) J. J. Northey et al. MOLECULAR AND CELLULAR BIOLOGY
- TRAF6 Mediates Smad-Independent Activation of JNK and p38 by TGF-β
- (2008) Motozo Yamashita et al. MOLECULAR CELL
- The type I TGF-β receptor is covalently modified and regulated by sumoylation
- (2008) Jong Seok Kang et al. NATURE CELL BIOLOGY
- The type I TGF-β receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner
- (2008) Alessandro Sorrentino et al. NATURE CELL BIOLOGY
- Critical regulation of TGF signaling by Hsp90
- (2008) K. H. Wrighton et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Progenitor/stem cells give rise to liver cancer due to aberrant TGF- and IL-6 signaling
- (2008) Y. Tang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now