HDAC 6 inhibitor ACY 1215 inhibits the activation of NLRP 3 inflammasome in acute liver failure by regulating the ATM/F ‐actin signalling pathway

A dopamine-precursor-based nanoprodrug for in-situ drug release and treatment of acute liver failure by inhibiting NLRP3 inflammasome and facilitating liver regeneration

(2020) Chenyue Zhan et al.   BIOMATERIALS

Modulation of calcium signaling pathway by hepatitis C virus core protein stimulates NLRP3 inflammasome activation

(2019) Amina A. Negash et al.   PLoS Pathogens

Connections between the cell cycle, cell adhesion and the cytoskeleton

(2019) Matthew C. Jones et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Inhibition of MELK produces potential anti‐tumour effects in bladder cancer by inducing G1/S cell cycle arrest via the ATM/CHK2/p53 pathway

(2019) Song Chen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Histone deacetylase inhibitor chidamide induces growth inhibition and apoptosis in NK/T lymphoma cells through ATM-Chk2-p53-p21 signalling pathway

(2018) Jianan Zhou et al.   INVESTIGATIONAL NEW DRUGS

Apoptosis and necroptosis in the liver: a matter of life and death

(2018) Robert F. Schwabe et al.   Nature Reviews Gastroenterology & Hepatology

Trichostatin A induces Trypanosoma cruzi histone and tubulin acetylation: effects on cell division and microtubule cytoskeleton remodelling

(2018) Jean de Oliveira Santos et al.   PARASITOLOGY

Histone Deacetylase Inhibitors as Anticancer Drugs

(2017) Tomas Eckschlager et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Role of the inflammasome in acetaminophen-induced liver injury and acute liver failure

(2017) Benjamin L. Woolbright et al.   JOURNAL OF HEPATOLOGY

NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice

(2017) Auvro R. Mridha et al.   JOURNAL OF HEPATOLOGY

Inflammasomes in Liver Fibrosis

(2017) Fernando Alegre et al.   SEMINARS IN LIVER DISEASE

Ataxia telangiectasia-mutated kinase deficiency exacerbates left ventricular dysfunction and remodeling late after myocardial infarction

(2016) Laura L. Daniel et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Macrophage autophagy limits acute toxic liver injury in mice through down regulation of interleukin-1β

(2016) Ghulam Ilyas et al.   JOURNAL OF HEPATOLOGY

F-actin dampens NLRP3 inflammasome activity via Flightless-I and LRRFIP2

(2016) Danielle Burger et al.   Scientific Reports

Evaluation of Cytotoxicity and DNA Damage Response with Analysis of Intracellular ATM Signaling Pathways

(2014) Sriram Bandi et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Mechanistic biomarkers in acetaminophen-induced hepatotoxicity and acute liver failure: from preclinical models to patients

(2014) Mitchell R McGill et al.   Expert Opinion on Drug Metabolism & Toxicology

Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome

(2013) Takuma Misawa et al.   NATURE IMMUNOLOGY

Acute Liver Failure

(2013) William Bernal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Middle Infrared Radiation Induces G2/M Cell Cycle Arrest in A549 Lung Cancer Cells

(2013) Hsin-Yi Chang et al.   PLoS One

Advances in the management of acute liver failure

(2013) Da-Wei Wang   WORLD JOURNAL OF GASTROENTEROLOGY

DNA Damage Sensing by the ATM and ATR Kinases

(2013) A. Marechal et al.   Cold Spring Harbor Perspectives in Biology

Perturbations in Ataxia Telangiectasia Mutant Signaling Pathways After Drug-Induced Acute Liver Failure and Their Reversal During Rescue of Animals by Cell Therapy

(2011) Sriram Bandi et al.   AMERICAN JOURNAL OF PATHOLOGY

Actin Structure and Function

(2011) Roberto Dominguez et al.   Annual Review of Biophysics

Acute liver failure

(2010) William Bernal et al.   LANCET

DNA damage response and cellular senescence in tissues of aging mice

(2009) Chunfang Wang et al.   AGING CELL

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

The γ-H2A.X: Is it just a surrogate marker of double-strand breaks or much more?

(2007) Ismail Hassan Ismail et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS