From OCR and ECAR to energy: perspectives on the design and interpretation of bioenergetics studies
出版年份 2021 全文链接
标题
From OCR and ECAR to energy: perspectives on the design and interpretation of bioenergetics studies
作者
关键词
bioenergetics, mitochondria, anaerobic glycolysis, cell metabolism, ATP
出版物
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume -, Issue -, Pages 101140
出版商
Elsevier BV
发表日期
2021-08-29
DOI
10.1016/j.jbc.2021.101140
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Aglycemic growth enhances carbohydrate metabolism and induces sensitivity to menadione in cultured tumor-derived cells
- (2021) Cameron A. Schmidt et al. Cancer & Metabolism
- Energy Metabolism Design of the Striated Muscle Cell
- (2021) Brian Glancy et al. PHYSIOLOGICAL REVIEWS
- Subcellular proteomics combined with bioenergetic phenotyping reveals protein biomarkers of respiratory insufficiency in the setting of proofreading-deficient mitochondrial polymerase
- (2020) Kelsey L. McLaughlin et al. Scientific Reports
- Warburg and Beyond: The Power of Mitochondrial Metabolism to Collaborate or Replace Fermentative Glycolysis in Cancer
- (2020) Shamir Cassim et al. Cancers
- Mapping mitochondrial respiratory chain deficiencies by respirometry: Beyond the Mito Stress Test
- (2020) Sausan M. Jaber et al. EXPERIMENTAL NEUROLOGY
- Flux through mitochondrial redox circuits linked to nicotinamide nucleotide transhydrogenase generates counterbalance changes in energy expenditure
- (2020) Cody D. Smith et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitochondrial ubiquinol oxidation is necessary for tumour growth
- (2020) Inmaculada Martínez-Reyes et al. NATURE
- Novel approach to quantify mitochondrial content and intrinsic bioenergetic efficiency across organs
- (2020) Kelsey L. McLaughlin et al. Scientific Reports
- Increased demand for NAD+ relative to ATP drives aerobic glycolysis
- (2020) Alba Luengo et al. MOLECULAR CELL
- MR (Mineralocorticoid Receptor) Induces Adipose Tissue Senescence and Mitochondrial Dysfunction Leading to Vascular Dysfunction in Obesity
- (2019) Clara Lefranc et al. HYPERTENSION
- Fasting reduces oxidative stress, mitochondrial dysfunction and fibrosis induced by renal ischemia-reperfusion injury
- (2019) Pedro Rojas-Morales et al. FREE RADICAL BIOLOGY AND MEDICINE
- Extensive metabolic remodeling after limiting mitochondrial lipid burden is consistent with an improved metabolic health profile
- (2019) Sujoy Ghosh et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Whys and Hows of Calculating Total Cellular ATP Production Rate
- (2019) Megan E. Handel et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Human and murine macrophages exhibit differential metabolic responses to lipopolysaccharide - A divergent role for glycolysis
- (2019) Vijith Vijayan et al. Redox Biology
- H+ transport is an integral function of the mitochondrial ADP/ATP carrier
- (2019) Ambre M. Bertholet et al. NATURE
- The combination of the glycolysis inhibitor 2-DG and sorafenib can be effective against sorafenib-tolerant persister cancer cells
- (2019) Li Wang et al. OncoTargets and Therapy
- Malate–aspartate shuttle promotes l ‐lactate oxidation in mitochondria
- (2019) Oya Altinok et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Near-equilibrium glycolysis supports metabolic homeostasis and energy yield
- (2019) Junyoung O. Park et al. Nature Chemical Biology
- A Compendium of Genetic Modifiers of Mitochondrial Dysfunction Reveals Intra-organelle Buffering
- (2019) Tsz-Leung To et al. CELL
- Cutting fuel offers new clues in diabetic mystery
- (2019) P. Darrell Neufer JOURNAL OF BIOLOGICAL CHEMISTRY
- Metabolic landscape of the tumor microenvironment at single cell resolution
- (2019) Zhengtao Xiao et al. Nature Communications
- Mitochondrial dysfunction and oxidative stress in heart disease
- (2019) Jessica N. Peoples et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Lactate dehydrogenase supports lactate oxidation in mitochondria isolated from different mouse tissues
- (2019) Adrian Young et al. Redox Biology
- Mitochondrial membrane potential
- (2018) Ljubava D. Zorova et al. ANALYTICAL BIOCHEMISTRY
- Lactate is oxidized outside of the mitochondrial matrix in rodent brain
- (2018) Eric A.F. Herbst et al. Applied Physiology Nutrition and Metabolism
- Mitochondrial Dysfunction in Parkinson’s Disease: New Mechanistic Insights and Therapeutic Perspectives
- (2018) Jin-Sung Park et al. Current Neurology and Neuroscience Reports
- High dietary fat intake increases fat oxidation and reduces skeletal muscle mitochondrial respiration in trained humans
- (2018) Jill J. Leckey et al. FASEB JOURNAL
- Assessment of mitochondrial function following short- and long-term exposure of human bronchial epithelial cells to total particulate matter from a candidate modified-risk tobacco product and reference cigarettes
- (2018) Dominika Malinska et al. FOOD AND CHEMICAL TOXICOLOGY
- Mitochondrial oxidative stress causes insulin resistance without disrupting oxidative phosphorylation
- (2018) Daniel J. Fazakerley et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Use the Protonmotive Force: Mitochondrial Uncoupling and Reactive Oxygen Species
- (2018) Brandon J. Berry et al. JOURNAL OF MOLECULAR BIOLOGY
- Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance
- (2018) Daniel J Fazakerley et al. eLife
- Four Key Steps Control Glycolytic Flux in Mammalian Cells
- (2018) Lukas Bahati Tanner et al. Cell Systems
- Bioenergetic consequences of compromised mitochondrial DNA repair in the mouse heart
- (2018) Kelsey L. McLaughlin et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Mitochondrial Diagnostics: A Multiplexed Assay Platform for Comprehensive Assessment of Mitochondrial Energy Fluxes
- (2018) Kelsey H. Fisher-Wellman et al. Cell Reports
- Measuring the functionality of the mitochondrial pumping complexes with multi-wavelength spectroscopy
- (2018) Mariana Rocha et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Uncoupling mechanism and redox regulation of mitochondrial uncoupling protein 1 (UCP1)
- (2018) Petr Ježek et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Evaluation of in Vitro Mitochondrial Toxicity Assays and Physicochemical Properties for Prediction of Organ Toxicity Using 228 Pharmaceutical Drugs
- (2018) Payal Rana et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Preadipocytes of obese humans display gender-specific bioenergetic responses to glucose and insulin
- (2018) Michaela Keuper et al. Molecular Metabolism
- Aglycemic HepG2 Cells Switch From Aminotransferase Glutaminolytic Pathway of Pyruvate Utilization to Complete Krebs Cycle at Hypoxia
- (2018) Jan Ježek et al. Frontiers in Endocrinology
- Quantifying intracellular rates of glycolytic and oxidative ATP production and consumption using extracellular flux measurements
- (2017) Shona A. Mookerjee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Glucose feeds the TCA cycle via circulating lactate
- (2017) Sheng Hui et al. NATURE
- Monitoring thioredoxin redox with a genetically encoded red fluorescent biosensor
- (2017) Yichong Fan et al. Nature Chemical Biology
- Genetically encoded fluorescent sensors reveal dynamic regulation of NADPH metabolism
- (2017) Rongkun Tao et al. NATURE METHODS
- Crosstalk of metabolic factors and neurogenic signaling in adult neurogenesis: Implication of metabolic regulation for mental and neurological diseases
- (2017) Chong Gao et al. NEUROCHEMISTRY INTERNATIONAL
- Perfect chemomechanical coupling of FoF1-ATP synthase
- (2017) Naoki Soga et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Bioenergetics of Exercise
- (2017) P. Darrell Neufer Cold Spring Harbor Perspectives in Medicine
- The effect of respiration buffer composition on mitochondrial metabolism and function
- (2017) Lucas C. Wollenman et al. PLoS One
- Direct real-time quantification of mitochondrial oxidative phosphorylation efficiency in permeabilized skeletal muscle myofibers
- (2016) Daniel S. Lark et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- UCPs, at the interface between bioenergetics and metabolism
- (2016) Frédéric Bouillaud et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Investigating mitochondrial redox state using NADH and NADPH autofluorescence
- (2016) Thomas S. Blacker et al. FREE RADICAL BIOLOGY AND MEDICINE
- Evidence That Does Not Support Pyruvate Kinase M2 (PKM2)-catalyzed Reaction as a Rate-limiting Step in Cancer Cell Glycolysis
- (2016) Jiansheng Xie et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Two distinct membrane potential–dependent steps drive mitochondrial matrix protein translocation
- (2016) Alexander Benjamin Schendzielorz et al. JOURNAL OF CELL BIOLOGY
- Flux Control in Glycolysis Varies Across the Tree of Life
- (2016) Alena Orlenko et al. JOURNAL OF MOLECULAR EVOLUTION
- The genetics and pathology of mitochondrial disease
- (2016) Charlotte L Alston et al. JOURNAL OF PATHOLOGY
- A Simple Hydraulic Analog Model of Oxidative Phosphorylation
- (2016) WAYNE T. WILLIS et al. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
- Glycolytic Enzymes Localize to Synapses under Energy Stress to Support Synaptic Function
- (2016) SoRi Jang et al. NEURON
- Biophysical comparison of ATP synthesis mechanisms shows a kinetic advantage for the rotary process
- (2016) Ramu Anandakrishnan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The CoQH2/CoQ Ratio Serves as a Sensor of Respiratory Chain Efficiency
- (2016) Adela Guarás et al. Cell Reports
- Determining Maximum Glycolytic Capacity Using Extracellular Flux Measurements
- (2016) Shona A. Mookerjee et al. PLoS One
- Underestimation of the Maximal Capacity of the Mitochondrial Electron Transport System in Oligomycin-Treated Cells
- (2016) Juliana S. Ruas et al. PLoS One
- Identification of KCa3.1 Channel as a Novel Regulator of Oxidative Phosphorylation in a Subset of Pancreatic Carcinoma Cell Lines
- (2016) Ilya Kovalenko et al. PLoS One
- Mitochondrial pyruvate transport: a historical perspective and future research directions
- (2015) Kyle S. McCommis et al. BIOCHEMICAL JOURNAL
- Pyruvate dehydrogenase complex and nicotinamide nucleotide transhydrogenase constitute an energy-consuming redox circuit
- (2015) Kelsey H. Fisher-Wellman et al. BIOCHEMICAL JOURNAL
- The contributions of respiration and glycolysis to extracellular acid production
- (2015) Shona A. Mookerjee et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Intracellular pH imaging in cancer cells in vitro and tumors in vivo using the new genetically encoded sensor SypHer2
- (2015) Marina V. Shirmanova et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis
- (2015) Kıvanç Birsoy et al. CELL
- Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells
- (2015) Lucas B. Sullivan et al. CELL
- Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis
- (2015) Simone Cardaci et al. NATURE CELL BIOLOGY
- A comparative analysis of inhibitors of the glycolysis pathway in breast and ovarian cancer cell line models
- (2015) Chrysi Xintaropoulou et al. Oncotarget
- Glutamine Oxidation Maintains the TCA Cycle and Cell Survival during Impaired Mitochondrial Pyruvate Transport
- (2014) Chendong Yang et al. MOLECULAR CELL
- Bioenergetic Analysis of Ovarian Cancer Cell Lines: Profiling of Histological Subtypes and Identification of a Mitochondria-Defective Cell Line
- (2014) Usawadee Dier et al. PLoS One
- UCP2 transports C4 metabolites out of mitochondria, regulating glucose and glutamine oxidation
- (2014) A. Vozza et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Quantitative determinants of aerobic glycolysis identify flux through the enzyme GAPDH as a limiting step
- (2014) Alexander A Shestov et al. eLife
- Mitochondrial Complex I
- (2013) Judy Hirst Annual Review of Biochemistry
- Animal models of disease: Pre-clinical animal models of cancer and their applications and utility in drug discovery
- (2013) Bruce A. Ruggeri et al. BIOCHEMICAL PHARMACOLOGY
- Effect of Calcium on the Oxidative Phosphorylation Cascade in Skeletal Muscle Mitochondria
- (2013) Brian Glancy et al. BIOCHEMISTRY
- Insulin acutely improves mitochondrial function of rat and human skeletal muscle by increasing coupling efficiency of oxidative phosphorylation
- (2013) Raid B. Nisr et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- "Deficiency" of Mitochondria in Muscle Does Not Cause Insulin Resistance
- (2013) J. O. Holloszy DIABETES
- Methods for Assessing Mitochondrial Function in Diabetes
- (2013) C. G. R. Perry et al. DIABETES
- Mitochondrial Respiratory Capacity and Content Are Normal in Young Insulin-Resistant Obese Humans
- (2013) K. H. Fisher-Wellman et al. DIABETES
- Overexpression of a key regulator of lipid homeostasis, Scap, promotes respiration in prostate cancer cells
- (2013) Anika Vinayak Prabhu et al. FEBS LETTERS
- Mammalian Complex I Pumps 4 Protons per 2 Electrons at High and Physiological Proton Motive Force in Living Cells
- (2013) Maureen O. Ripple et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Selective inhibition of ATPase activity during contraction alters the activation of p38 MAP kinase isoforms in skeletal muscle
- (2013) Jeffrey J. Brault et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- A bioenergetic profile of non-transformed fibroblasts uncovers a link between death-resistance and enhanced spare respiratory capacity
- (2013) Kristen P. Nickens et al. MITOCHONDRION
- Glutamine-driven oxidative phosphorylation is a major ATP source in transformed mammalian cells in both normoxia and hypoxia
- (2013) J. Fan et al. Molecular Systems Biology
- Mitochondrially targeted compounds and their impact on cellular bioenergetics
- (2013) Colin Reily et al. Redox Biology
- Integration of cellular bioenergetics with mitochondrial quality control and autophagy
- (2012) Bradford G. Hill et al. BIOLOGICAL CHEMISTRY
- The use of animal models in diabetes research
- (2012) Aileen JF King BRITISH JOURNAL OF PHARMACOLOGY
- Lipid-Induced Mitochondrial Stress and Insulin Action in Muscle
- (2012) Deborah M. Muoio et al. Cell Metabolism
- The contribution of oxidative stress to drug-induced organ toxicity and its detectionin vitroandin vivo
- (2012) Claudia V Pereira et al. Expert Opinion on Drug Metabolism & Toxicology
- Early alterations in mitochondrial reserve capacity; a means to predict subsequent photoreceptor cell death
- (2012) Nathan R. Perron et al. JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
- Determinants of intra-specific variation in basal metabolic rate
- (2012) Marek Konarzewski et al. JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTAL PHYSIOLOGY
- Rethinking glycolysis: on the biochemical logic of metabolic pathways
- (2012) Arren Bar-Even et al. Nature Chemical Biology
- Switching from aerobic glycolysis to oxidative phosphorylation modulates the sensitivity of mantle cell lymphoma cells to TRAIL
- (2012) G L Robinson et al. ONCOGENE
- Linking mitochondrial bioenergetics to insulin resistance via redox biology
- (2012) Kelsey H. Fisher-Wellman et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Assessing mitochondrial dysfunction in cells
- (2011) Martin D. Brand et al. BIOCHEMICAL JOURNAL
- Mitochondrial membrane potential probes and the proton gradient: a practical usage guide
- (2011) Seth W. Perry et al. BIOTECHNIQUES
- Exogenous pyruvate accelerates glycolysis and promotes capacitation in human spermatozoa
- (2011) T.H. Hereng et al. HUMAN REPRODUCTION
- Comparative bioenergetic assessment of transformed cells using a cell energy budget platform
- (2011) A. V. Zhdanov et al. Integrative Biology
- The monocarboxylate transporter family-Role and regulation
- (2011) Andrew P. Halestrap et al. IUBMB LIFE
- Mitochondrial ATP synthase: architecture, function and pathology
- (2011) An I. Jonckheere et al. JOURNAL OF INHERITED METABOLIC DISEASE
- Reductive carboxylation supports growth in tumour cells with defective mitochondria
- (2011) Andrew R. Mullen et al. NATURE
- The Human Serum Metabolome
- (2011) Nikolaos Psychogios et al. PLoS One
- Reduced Coupling of Oxidative Phosphorylation In Vivo Precedes Electron Transport Chain Defects Due to Mild Oxidative Stress in Mice
- (2011) Michael P. Siegel et al. PLoS One
- Bioenergetic characterization of mouse podocytes
- (2010) Yoshifusa Abe et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Mitochondrial fission and remodelling contributes to muscle atrophy
- (2010) Vanina Romanello et al. EMBO JOURNAL
- Mitochondrial reserve capacity in endothelial cells: The impact of nitric oxide and reactive oxygen species
- (2010) Brian P. Dranka et al. FREE RADICAL BIOLOGY AND MEDICINE
- Monitoring of cell oxygenation and responses to metabolic stimulation by intracellular oxygen sensing technique
- (2010) Alexander V. Zhdanov et al. Integrative Biology
- Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis
- (2010) Vishal M Gohil et al. NATURE BIOTECHNOLOGY
- The benefits and limitations of animal models for translational research in neurodegenerative diseases
- (2010) Mathias Jucker NATURE MEDICINE
- Insulin signaling meets mitochondria in metabolism
- (2010) Zhiyong Cheng et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- In vitro analysis of cell metabolism using a long-decay pH-sensitive lanthanide probe and extracellular acidification assay
- (2009) James Hynes et al. ANALYTICAL BIOCHEMISTRY
- Quantitative Microplate-Based Respirometry with Correction for Oxygen Diffusion
- (2009) Akos A. Gerencser et al. ANALYTICAL CHEMISTRY
- Intramuscular triacylglycerol and insulin resistance: Guilty as charged or wrongly accused?
- (2009) Deborah M. Muoio BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Importing Mitochondrial Proteins: Machineries and Mechanisms
- (2009) Agnieszka Chacinska et al. CELL
- Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans
- (2009) Ethan J. Anderson et al. JOURNAL OF CLINICAL INVESTIGATION
- Bioenergetic analysis of isolated cerebrocortical nerve terminals on a microgram scale: spare respiratory capacity and stochastic mitochondrial failure
- (2009) Sung W. Choi et al. JOURNAL OF NEUROCHEMISTRY
- How mitochondria produce reactive oxygen species
- (2008) Michael P. Murphy BIOCHEMICAL JOURNAL
- The ADP and ATP transport in mitochondria and its carrier
- (2008) Martin Klingenberg BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Lower Intrinsic ADP-Stimulated Mitochondrial Respiration Underlies In Vivo Mitochondrial Dysfunction in Muscle of Male Type 2 Diabetic Patients
- (2008) E. Phielix et al. DIABETES
- Regulation of oxidative phosphorylation, the mitochondrial membrane potential, and their role in human disease
- (2008) Maik Hüttemann et al. JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
- ATP Synthase and the Actions of Inhibitors Utilized To Study Its Roles in Human Health, Disease, and Other Scientific Areas
- (2008) S. Hong et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- High-fat diets cause insulin resistance despite an increase in muscle mitochondria
- (2008) C. R. Hancock et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Biguanide-induced mitochondrial dysfunction yields increased lactate production and cytotoxicity of aerobically-poised HepG2 cells and human hepatocytes in vitro
- (2008) James A. Dykens et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
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