Transcriptome landscape of double negative T cells by single-cell RNA sequencing

Systemic lupus erythematosus favors the generation of IL-17 producing double negative T cells

(2020) Hao Li et al.   Nature Communications

DoubletFinder: Doublet Detection in Single-Cell RNA Sequencing Data Using Artificial Nearest Neighbors

(2019) Christopher S. McGinnis et al.   Cell Systems

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Reparative T lymphocytes in organ injury

(2019) Franco R. D’Alessio et al.   JOURNAL OF CLINICAL INVESTIGATION

Ikaros Zinc Finger Transcription Factors: Regulators of Cytokine Signaling Pathways and CD4+ T Helper Cell Differentiation

(2019) Michael D. Powell et al.   Frontiers in Immunology

The biology and functional importance of MAIT cells

(2019) Dale I. Godfrey et al.   NATURE IMMUNOLOGY

Microbial metabolites control the thymic development of mucosal-associated invariant T cells

(2019) François Legoux et al.   SCIENCE

Fast, sensitive and accurate integration of single-cell data with Harmony

(2019) Ilya Korsunsky et al.   NATURE METHODS

Double negative T cells mediate Lag3-dependent antigen-specific protection in allergic asthma

(2019) Dan Tian et al.   Nature Communications

DoubletDecon: Deconvoluting Doublets from Single-Cell RNA-Sequencing Data

(2019) Erica A.K. DePasquale et al.   Cell Reports

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Infusion of ex-vivo expanded human TCR-αβ+ double-negative regulatory T cells delays onset of xenogeneic graft-versus -host disease

(2018) P. Achita et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

High-Dimensional Single-Cell Analysis Identifies Organ-Specific Signatures and Conserved NK Cell Subsets in Humans and Mice

(2018) Adeline Crinier et al.   IMMUNITY

Dimensionality reduction for visualizing single-cell data using UMAP

(2018) Etienne Becht et al.   NATURE BIOTECHNOLOGY

Concomitant Disruption ofCD4andCD8Genes Facilitates the Development of Double Negative αβ TCR+Peripheral T Cells That Respond Robustly to Staphylococcal Superantigen

(2017) Vaidehi R. Chowdhary et al.   JOURNAL OF IMMUNOLOGY

A three-stage intrathymic development pathway for the mucosal-associated invariant T cell lineage

(2016) Hui-Fern Koay et al.   NATURE IMMUNOLOGY

A novel differentiation pathway from CD4+ T cells to CD4− T cells for maintaining immune system homeostasis

(2016) X Zhao et al.   Cell Death & Disease

The mystery of BCL2 family: Bcl-2 proteins and apoptosis: an update

(2015) Waseem Ahmad Siddiqui et al.   ARCHIVES OF TOXICOLOGY

CXCR6 regulates the recruitment of pro-inflammatory IL-17A-producing T cells into atherosclerotic aortas

(2015) Matthew J. Butcher et al.   INTERNATIONAL IMMUNOLOGY

Identification of phenotypically and functionally heterogeneous mouse mucosal-associated invariant T cells using MR1 tetramers

(2015) Azad Rahimpour et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-7 Abrogates the Immunosuppressive Function of Human Double-Negative T Cells by Activating Akt/mTOR Signaling

(2015) Andrea Allgäuer et al.   JOURNAL OF IMMUNOLOGY

Double-negative T resident memory cells of the lung react to influenza virus infection via CD11chi dendritic cells

(2015) K Neyt et al.   Mucosal Immunology

Spatial reconstruction of single-cell gene expression data

(2015) Rahul Satija et al.   NATURE BIOTECHNOLOGY

Advances on Non-CD4 + Foxp3+ T Regulatory Cells

(2015) Ann J. Ligocki et al.   TRANSPLANTATION

Helios defines T cells being driven to tolerance in the periphery and thymus

(2014) Ellen M. Ross et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The activating Ly49W and inhibitory Ly49G NK cell receptors display similar affinities for identical MHC class I ligands

(2014) Brian J. Ma et al.   IMMUNOGENETICS

Ex vivo converted double negative T cells suppress activated B cells

(2014) WenXia Li et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

CD4−CD8− T-cells in primary Sjögren's syndrome: Association with the extent of glandular involvement

(2014) Alessia Alunno et al.   JOURNAL OF AUTOIMMUNITY

Expanded Double Negative T Cells in Patients with Systemic Lupus Erythematosus Produce IL-17 and Infiltrate the Kidneys

(2014) J. C. Crispin et al.   JOURNAL OF IMMUNOLOGY

MHC Class II Restricted Innate-Like Double Negative T Cells Contribute to Optimal Primary and Secondary Immunity to Leishmania major

(2014) Zhirong Mou et al.   PLoS Pathogens

Regulation of TH17 markers early in life through maternal farm exposure

(2013) Anna Lluis et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Immunoregulatory CD4-CD8- T cells as a potential therapeutic tool for transplantation, autoimmunity, and cancer

(2013) Erin E. Hillhouse et al.   Frontiers in Immunology

IL-17-producing CD4−CD8−T cells are expanded in the peripheral blood, infiltrate salivary glands and are resistant to corticosteroids in patients with primary Sjögren's syndrome

(2012) Alessia Alunno et al.   ANNALS OF THE RHEUMATIC DISEASES

Double negative Treg cells promote nonmyeloablative bone marrow chimerism by inducing T-cell clonal deletion and suppressing NK cell function

(2012) Ye Su et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis

(2012) P. Ramachandran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Double negative regulatory T cells in transplantation and autoimmunity: recent progress and future directions

(2012) S. C. Juvet et al.   Journal of Molecular Cell Biology

Adoptive cell therapy using antigen-specific CD4−CD8− T regulatory cells to prevent autoimmune diabetes and promote islet allograft survival in NOD mice

(2011) D. Zhang et al.   DIABETOLOGIA

Regulation of antigen-expressing dendritic cells by double negative regulatory T cells

(2011) Julia Fang Gao et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Lung CD4-CD8- Double-Negative T Cells Are Prominent Producers of IL-17A and IFN-  during Primary Respiratory Murine Infection with Francisella tularensis Live Vaccine Strain

(2010) S. C. Cowley et al.   JOURNAL OF IMMUNOLOGY

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

(2009) Gabriela Bindea et al.   BIOINFORMATICS

Human TCR-  + CD4- CD8- T Cells Can Derive from CD8+ T Cells and Display an Inflammatory Effector Phenotype

(2009) J. C. Crispin et al.   JOURNAL OF IMMUNOLOGY

Influence of CRACC, a SLAM family receptor coupled to the adaptor EAT-2, on natural killer cell function

(2009) Mario-Ernesto Cruz-Munoz et al.   NATURE IMMUNOLOGY

Interleukin 17 acts in synergy with B cell–activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus

(2009) Agnès Doreau et al.   NATURE IMMUNOLOGY

Inflammation-associated lysophospholipids as ligands for CD1d-restricted T cells in human cancer

(2008) D. H. Chang et al.   BLOOD