Phosphorylation of SARS-CoV-2 Orf9b Regulates Its Targeting to Two Binding Sites in TOM70 and Recruitment of Hsp90

Estimated transmissibility and impact of SARS-CoV-2 lineage B.1.1.7 in England

(2021) Nicholas G. Davies et al.   SCIENCE

Characteristics of SARS-CoV-2 variants of concern B.1.1.7, B.1.351 or P.1: data from seven EU/EEA countries, weeks 38/2020 to 10/2021

(2021) Tjede Funk et al.   Eurosurveillance

SARS‐CoV‐2 ORF9b antagonizes type I and III interferons by targeting multiple components of the RIG‐I/MDA‐5–MAVS, TLR3–TRIF, and cGAS–STING signaling pathways

(2021) Lulu Han et al.   JOURNAL OF MEDICAL VIROLOGY

Increased mortality in community-tested cases of SARS-CoV-2 lineage B.1.1.7

(2021) Nicholas G. Davies et al.   NATURE

Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England

(2021) Erik Volz et al.   NATURE

Predictable fold switching by the SARS‐CoV ‐2 protein ORF9b

(2021) Lauren L. Porter   PROTEIN SCIENCE

Crystal structure of SARS-CoV-2 Orf9b in complex with human TOM70 suggests unusual virus-host interactions

(2021) Xiaopan Gao et al.   Nature Communications

The chaperone-binding activity of the mitochondrial surface receptor Tom70 protects the cytosol against mitoprotein-induced stress

(2021) Sandra Backes et al.   Cell Reports

Biogenesis pathways of α-helical mitochondrial outer membrane proteins

(2020) Layla Drwesh et al.   BIOLOGICAL CHEMISTRY

The mitochondrial carrier pathway transports non-canonical substrates with an odd number of transmembrane segments

(2020) Heike Rampelt et al.   BMC BIOLOGY

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

(2020) Daniel Blanco-Melo et al.   CELL

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

(2020) David E. Gordon et al.   NATURE

Cytosolic Events in the Biogenesis of Mitochondrial Proteins

(2020) Yury S. Bykov et al.   TRENDS IN BIOCHEMICAL SCIENCES

The Global Phosphorylation Landscape of SARS-CoV-2 Infection

(2020) Mehdi Bouhaddou et al.   CELL

SARS-CoV-2 Orf9b suppresses type I interferon responses by targeting TOM70

(2020) He-wei Jiang et al.   Cellular & Molecular Immunology

A Comprehensive, Flexible Collection of SARS-CoV-2 Coding Regions

(2020) Dae-Kyum Kim et al.   G3-Genes Genomes Genetics

The Mitochondrial Outer Membrane Protein Tom70-Mediator in Protein Traffic, Membrane Contact Sites and Innate Immunity

(2020) Sebastian Kreimendahl et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms

(2020) David E. Gordon et al.   SCIENCE

Mitochondrial metabolic manipulation by SARS-CoV-2 in peripheral blood mononuclear cells of patients with COVID-19

(2020) Saima Ajaz et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The tetratricopeptide-repeat motif is a versatile platform that enables diverse modes of molecular recognition

(2019) Albert Perez-Riba et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Versatility of Preprotein Transfer from the Cytosol to Mitochondria

(2019) Thomas Becker et al.   TRENDS IN CELL BIOLOGY

The HSP90 chaperone machinery

(2017) Florian H. Schopf et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Molecular Chaperone Functions in Protein Folding and Proteostasis

(2013) Yujin E. Kim et al.   Annual Review of Biochemistry

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

FastCloning: a highly simplified, purification-free, sequence- and ligation-independent PCR cloning method

(2011) Chaokun Li et al.   BMC BIOTECHNOLOGY

Function of Cytosolic Chaperones in Tom70-Mediated Mitochondrial Import

(2011) Anna C.Y. Fan et al.   PROTEIN AND PEPTIDE LETTERS

The structural plasticity of Tom71 for mitochondrial precursor translocations

(2010) Jingzhi Li et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Tom70 mediates activation of interferon regulatory factor 3 on mitochondria

(2010) Xin-Yi Liu et al.   CELL RESEARCH

Molecular Chaperone Hsp70/Hsp90 Prepares the Mitochondrial Outer Membrane Translocon Receptor Tom71 for Preprotein Loading

(2009) Jingzhi Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Roles of Tom70 in Import of Presequence-containing Mitochondrial Proteins

(2009) Hayashi Yamamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY