标题
CAR-NK Cells in the Treatment of Solid Tumors
作者
关键词
-
出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 22, Issue 11, Pages 5899
出版商
MDPI AG
发表日期
2021-05-31
DOI
10.3390/ijms22115899
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- GMP-Compliant Universal Antigen Presenting Cells (uAPC) Promote the Metabolic Fitness and Antitumor Activity of Armored Cord Blood CAR-NK Cells
- (2021) Enli Liu et al. Frontiers in Immunology
- Natural Killer Cells and Anti-Cancer Therapies: Reciprocal Effects on Immune Function and Therapeutic Response
- (2021) Elisa C. Toffoli et al. Cancers
- Optimizing the Procedure to Manufacture Clinical-Grade NK Cells for Adoptive Immunotherapy
- (2021) Adrián Fernández et al. Cancers
- Chimeric antigen receptor engineered NK cellular immunotherapy overcomes the selection of T-cell escape variant cancer cells
- (2021) Maxwell Y Lee et al. Journal for ImmunoTherapy of Cancer
- Use of chimeric antigen receptor NK-92 cells to target mesothelin in ovarian cancer
- (2020) Bihui Cao et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Use of CAR-Transduced Natural Killer Cells in CD19-Positive Lymphoid Tumors
- (2020) Enli Liu et al. NEW ENGLAND JOURNAL OF MEDICINE
- Tumor heterogeneity and clonal cooperation influence the immune selection of IFN-γ-signaling mutant cancer cells
- (2020) Jason B. Williams et al. Nature Communications
- Tissue factor as a new target for CAR-NK cell immunotherapy of triple-negative breast cancer
- (2020) Zhiwei Hu Scientific Reports
- Boosting Natural Killer Cell-Mediated Targeting of Sarcoma Through DNAM-1 and NKG2D
- (2020) Ece Canan Sayitoglu et al. Frontiers in Immunology
- Targeting CD38-Expressing Multiple Myeloma and Burkitt Lymphoma Cells In Vitro with Nanobody-Based Chimeric Antigen Receptors (Nb-CARs)
- (2020) Julia Hambach et al. Cells
- Inhibition of MICA and MICB Shedding Elicits NK-Cell–Mediated Immunity against Tumors Resistant to Cytotoxic T Cells
- (2020) Lucas Ferrari de Andrade et al. Cancer Immunology Research
- NKG2D Ligand Shedding in Response to Stress: Role of ADAM10
- (2020) Alessandra Zingoni et al. Frontiers in Immunology
- DNAM1 and 2B4 Costimulatory Domains Enhance the Cytotoxicity of Anti-GPC3 Chimeric Antigen Receptor-Modified Natural Killer Cells Against Hepatocellular Cancer Cells in vitro
- (2020) Yao Huang et al. Cancer Management and Research
- Overcoming Heterogeneity of Antigen Expression for Effective CAR T Cell Targeting of Cancers
- (2020) Sareetha Kailayangiri et al. Cancers
- CAR-modified memory-like NK cells exhibit potent responses to NK-resistant lymphomas
- (2020) Margery Gang et al. BLOOD
- A novel chimeric PD1-NKG2D-41BB receptor enhances antitumor activity of NK92 cells against human lung cancer H1299 cells by triggering pyroptosis
- (2020) Chengui Lu et al. MOLECULAR IMMUNOLOGY
- CAR-T design: Elements and their synergistic function
- (2020) Jayapriya Jayaraman et al. EBioMedicine
- Nanobodies: Next Generation of Cancer Diagnostics and Therapeutics
- (2020) Emily Y. Yang et al. Frontiers in Oncology
- Human NK-92 Cells Function as Target Cells for Human NK Cells – Implications for CAR NK-92 Therapies
- (2020) HANS BERGMAN et al. ANTICANCER RESEARCH
- Targeting a cytokine checkpoint enhances the fitness of armored cord blood CAR-NK cells
- (2020) May Daher et al. BLOOD
- Rationally designed redirection of natural killer cells anchoring a cytotoxic ligand for pancreatic cancer treatment
- (2020) Young Eun Lee et al. JOURNAL OF CONTROLLED RELEASE
- Superior Expansion and Cytotoxicity of Human Primary NK and CAR-NK Cells from Various Sources via Enriched Metabolic Pathways
- (2020) Yan Yang et al. Molecular Therapy-Methods & Clinical Development
- Stroma-Targeting Therapy in Pancreatic Cancer: One Coin With Two Sides?
- (2020) Bolun Jiang et al. Frontiers in Oncology
- Chimeric antigen receptor (CAR) natural killer (NK)‐cell therapy: leveraging the power of innate immunity
- (2020) Hind Rafei et al. BRITISH JOURNAL OF HAEMATOLOGY
- NK cell infiltration is associated with improved overall survival in solid cancers: A systematic review and meta-analysis
- (2020) Sarah Nersesian et al. Translational Oncology
- Next-generation cell therapies: the emerging role of CAR-NK cells
- (2020) Rafet Basar et al. Blood Advances
- Therapeutic Potential of Natural Killer Cells in Gastric Cancer
- (2019) Yu Du et al. Frontiers in Immunology
- Characterization of a Novel Third-Generation Anti-CD24-CAR against Ovarian Cancer
- (2019) Rüdiger Klapdor et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- IL-15 by continuous i.v. infusion to adult patients with solid tumors in a Phase I trial induced dramatic NK cell subset expansion
- (2019) Kevin C Conlon et al. CLINICAL CANCER RESEARCH
- 2B4 costimulatory domain enhancing cytotoxic ability of anti-CD5 chimeric antigen receptor engineered natural killer cells against T cell malignancies
- (2019) Yingxi Xu et al. Journal of Hematology & Oncology
- Cancer stem cells: A review from origin to therapeutic implications
- (2019) Mohammad Reza Atashzar et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Anti-αFR CAR-engineered NK-92 Cells Display Potent Cytotoxicity Against αFR-positive Ovarian Cancer
- (2019) Xiang Ao et al. JOURNAL OF IMMUNOTHERAPY
- Development of c‑MET‑specific chimeric antigen receptor‑engineered natural killer cells with cytotoxic effects on human liver cancer HepG2 cells
- (2019) Bing Liu et al. Molecular Medicine Reports
- Myeloid Derived Suppressor Cells Interactions With Natural Killer Cells and Pro-angiogenic Activities: Roles in Tumor Progression
- (2019) Antonino Bruno et al. Frontiers in Immunology
- IL-27 enhances IL-15/IL-18-mediated activation of human natural killer cells
- (2019) Yeon Ho Choi et al. Journal for ImmunoTherapy of Cancer
- Robo1-specific CAR-NK Immunotherapy Enhances Efficacy of 125I Seed Brachytherapy in an Orthotopic Mouse Model of Human Pancreatic Carcinoma
- (2019) NING XIA et al. ANTICANCER RESEARCH
- CAR-NK for tumor immunotherapy: Clinical transformation and future prospects
- (2019) Wenxiu Wang et al. CANCER LETTERS
- Impairment of NKG2D-Mediated Tumor Immunity by TGF-β
- (2019) Mariya Lazarova et al. Frontiers in Immunology
- NK Cell-Based Immunotherapy for Hematological Malignancies
- (2019) Simona Sivori et al. Journal of Clinical Medicine
- Targeting T cell malignancies using CAR-based immunotherapy: challenges and potential solutions
- (2019) Lauren C. Fleischer et al. Journal of Hematology & Oncology
- Engineering strategies to overcome the current roadblocks in CAR T cell therapy
- (2019) Sarwish Rafiq et al. Nature Reviews Clinical Oncology
- Adult peripheral blood and umbilical cord blood NK cells are good sources for effective CAR therapy against CD19 positive leukemic cells
- (2019) L. Herrera et al. Scientific Reports
- The Synergistic Use of IL-15 and IL-21 for the Generation of NK Cells From CD3/CD19-Depleted Grafts Improves Their ex vivo Expansion and Cytotoxic Potential Against Neuroblastoma: Perspective for Optimized Immunotherapy Post Haploidentical Stem Cell Transplantation
- (2019) Annekathrin Heinze et al. Frontiers in Immunology
- CXCR1 Expression to Improve Anti-Cancer Efficacy of Intravenously Injected CAR-NK Cells in Mice with Peritoneal Xenografts
- (2019) Yu Yang Ng et al. Molecular Therapy-Oncolytics
- Human iPSC-Derived Natural Killer Cells Engineered with Chimeric Antigen Receptors Enhance Anti-tumor Activity
- (2018) Ye Li et al. Cell Stem Cell
- Inhibition of IL-6-JAK/Stat3 signaling in castration-resistant prostate cancer cells enhances the NK cell-mediated cytotoxicity via alteration of PD-L1/NKG2D ligand levels
- (2018) LiJun Xu et al. Molecular Oncology
- Blockade of the checkpoint receptor TIGIT prevents NK cell exhaustion and elicits potent anti-tumor immunity
- (2018) Qing Zhang et al. NATURE IMMUNOLOGY
- Antibody-mediated inhibition of MICA and MICB shedding promotes NK cell–driven tumor immunity
- (2018) Lucas Ferrari de Andrade et al. SCIENCE
- Adaptive NK Cells Resist Regulatory T-cell Suppression Driven by IL37
- (2018) Dhifaf Sarhan et al. Cancer Immunology Research
- The Generation of CAR-Transfected Natural Killer T Cells for the Immunotherapy of Melanoma
- (2018) Bianca Simon et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Lack of FcRn Impairs Natural Killer Cell Development and Functions in the Tumor Microenvironment
- (2018) Diana Cadena Castaneda et al. Frontiers in Immunology
- Adoptive cellular therapies: the current landscape
- (2018) Maartje W. Rohaan et al. VIRCHOWS ARCHIV
- An antibody designed to improve adoptive NK-cell therapy inhibits pancreatic cancer progression in a murine model
- (2018) Jaemin Lee et al. Cancer Immunology Research
- Combination Therapy with EpCAM-CAR-NK-92 Cells and Regorafenib against Human Colorectal Cancer Models
- (2018) Qing Zhang et al. Journal of Immunology Research
- Preclinical targeting of aggressive T-cell malignancies using anti-CD5 chimeric antigen receptor
- (2017) K H Chen et al. LEUKEMIA
- Cord blood NK cells engineered to express IL-15 and a CD19-targeted CAR show long-term persistence and potent antitumor activity
- (2017) E Liu et al. LEUKEMIA
- A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma
- (2017) Donald M. O’Rourke et al. Science Translational Medicine
- Ipilimumab treatment decreases monocytic MDSCs and increases CD8 effector memory T cells in long-term survivors with advanced melanoma
- (2017) Yago Pico de Coana et al. Oncotarget
- Synergistic Effects of Cabozantinib and EGFR-Specific CAR-NK-92 Cells in Renal Cell Carcinoma
- (2017) Qing Zhang et al. Journal of Immunology Research
- Developmental and Functional Control of Natural Killer Cells by Cytokines
- (2017) Yang Wu et al. Frontiers in Immunology
- Umbilical Cord Blood Natural Killer Cells, Their Characteristics, and Potential Clinical Applications
- (2017) Anushruti Sarvaria et al. Frontiers in Immunology
- The histone deacetylase inhibitor valproic acid inhibits NKG2D expression in natural killer cells through suppression of STAT3 and HDAC3
- (2017) Lulu Ni et al. Scientific Reports
- Adaptive NK Cells with Low TIGIT Expression Are Inherently Resistant to Myeloid-Derived Suppressor Cells
- (2016) Dhifaf Sarhan et al. CANCER RESEARCH
- Liver-infiltrating CD11b−CD27− NK subsets account for NK-cell dysfunction in patients with hepatocellular carcinoma and are associated with tumor progression
- (2016) Qiong-Fang Zhang et al. Cellular & Molecular Immunology
- Targeting Cancer Stem Cells with Natural Killer Cell Immunotherapy
- (2016) Jesus I. Luna et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy
- (2016) Christine E. Brown et al. NEW ENGLAND JOURNAL OF MEDICINE
- Bioactivity and Safety of IL13R 2-Redirected Chimeric Antigen Receptor CD8+ T Cells in Patients with Recurrent Glioblastoma
- (2015) C. E. Brown et al. CLINICAL CANCER RESEARCH
- Cytomegalovirus Infection Drives Adaptive Epigenetic Diversification of NK Cells with Altered Signaling and Effector Function
- (2015) Heinrich Schlums et al. IMMUNITY
- Epigenetic Modification and Antibody-Dependent Expansion of Memory-like NK Cells in Human Cytomegalovirus-Infected Individuals
- (2015) Jaewon Lee et al. IMMUNITY
- NK Cells Preferentially Target Tumor Cells with a Cancer Stem Cell Phenotype
- (2015) Erik Ames et al. JOURNAL OF IMMUNOLOGY
- DAP12-Based Activating Chimeric Antigen Receptor for NK Cell Tumor Immunotherapy
- (2015) Katrin Töpfer et al. JOURNAL OF IMMUNOLOGY
- Engineering NK Cells Modified With an EGFRvIII-specific Chimeric Antigen Receptor to Overexpress CXCR4 Improves Immunotherapy of CXCL12/SDF-1α-secreting Glioblastoma
- (2015) Nadja Müller et al. JOURNAL OF IMMUNOTHERAPY
- Selective Inhibition of Tumor Growth by Clonal NK Cells Expressing an ErbB2/HER2-Specific Chimeric Antigen Receptor
- (2015) Kurt Schönfeld et al. MOLECULAR THERAPY
- Induced Pluripotent Stem Cell-Derived Natural Killer Cells for Treatment of Ovarian Cancer
- (2015) David L. Hermanson et al. STEM CELLS
- NKG2D and DNAM-1 Ligands: Molecular Targets for NK Cell-Mediated Immunotherapeutic Intervention in Multiple Myeloma
- (2015) Cinzia Fionda et al. Biomed Research International
- Dual targeting of glioblastoma with chimeric antigen receptor-engineered natural killer cells overcomes heterogeneity of target antigen expression and enhances antitumor activity and survival
- (2015) Sabrina Genßler et al. OncoImmunology
- CAR-Engineered NK Cells Targeting Wild-Type EGFR and EGFRvIII Enhance Killing of Glioblastoma and Patient-Derived Glioblastoma Stem Cells
- (2015) Jianfeng Han et al. Scientific Reports
- Clearance of acute myeloid leukemia by haploidentical natural killer cells is improved using IL-2 diphtheria toxin fusion protein
- (2014) V. Bachanova et al. BLOOD
- Current concepts in the diagnosis and management of cytokine release syndrome
- (2014) D. W. Lee et al. BLOOD
- MicroRNA-218 inhibits cell invasion and migration of pancreatic cancer via regulating ROBO1
- (2014) Hang He et al. CANCER BIOLOGY & THERAPY
- Doxorubicin Eliminates Myeloid-Derived Suppressor Cells and Enhances the Efficacy of Adoptive T-Cell Transfer in Breast Cancer
- (2013) D. Alizadeh et al. CANCER RESEARCH
- A Chimeric Receptor with NKG2D Specificity Enhances Natural Killer Cell Activation and Killing of Tumor Cells
- (2013) Y.-H. Chang et al. CANCER RESEARCH
- Modulation of NKG2D ligand expression and metastasis in tumors by spironolactone via RXRγ activation
- (2013) Wai-Hang Leung et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Inhibition of Glycogen Synthase Kinase-3 Increases NKG2D Ligand MICA Expression and Sensitivity to NK Cell-Mediated Cytotoxicity in Multiple Myeloma Cells: Role of STAT3
- (2013) C. Fionda et al. JOURNAL OF IMMUNOLOGY
- Clinical-Scale Derivation of Natural Killer Cells From Human Pluripotent Stem Cells for Cancer Therapy
- (2013) David A. Knorr et al. Stem Cells Translational Medicine
- Cytokine activation induces human memory-like NK cells
- (2012) R. Romee et al. BLOOD
- Expression of IL-15 in NK cells results in rapid enrichment and selective cytotoxicity of gene-modified effectors that carry a tumor-specific antigen receptor
- (2012) Christiane Sahm et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Sustained effector function of IL-12/15/18–preactivated NK cells against established tumors
- (2012) Jing Ni et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Human Cytomegalovirus (CMV)-Induced Memory-like NKG2C+ NK Cells Are Transplantable and Expand In Vivo in Response to Recipient CMV Antigen
- (2012) B. Foley et al. JOURNAL OF IMMUNOLOGY
- The unique profile of cord blood natural killer cells balances incomplete maturation and effective killing function upon activation
- (2011) Martha Luevano et al. HUMAN IMMUNOLOGY
- Tumor Evasion from T Cell Surveillance
- (2011) Katrin Töpfer et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
- Modulation of NKG2D-ligand Cell Surface Expression Enhances Immune Cell Therapy of Cancer
- (2011) Baocheng Huang et al. JOURNAL OF IMMUNOTHERAPY
- 5-Fluorouracil Selectively Kills Tumor-Associated Myeloid-Derived Suppressor Cells Resulting in Enhanced T Cell-Dependent Antitumor Immunity
- (2010) J. Vincent et al. CANCER RESEARCH
- A phase II study of allogeneic natural killer cell therapy to treat patients with recurrent ovarian and breast cancer
- (2010) Melissa A. Geller et al. CYTOTHERAPY
- Sunitinib Mediates Reversal of Myeloid-Derived Suppressor Cell Accumulation in Renal Cell Carcinoma Patients
- (2009) J. S. Ko et al. CLINICAL CANCER RESEARCH
- Natural killer cell cytotoxicity: how do they pull the trigger?
- (2009) Nicola J. Topham et al. IMMUNOLOGY
- DAP10- and DAP12-associated receptors in innate immunity
- (2008) Lewis L. Lanier IMMUNOLOGICAL REVIEWS
- CD56brightnatural killer (NK) cells: an important NK cell subset
- (2008) Aurélie Poli et al. IMMUNOLOGY
- Permanent silencing of NKG2A expression for cell-based therapeutics
- (2008) Constança Figueiredo et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Functions of natural killer cells
- (2008) Eric Vivier et al. NATURE IMMUNOLOGY
- Engineering antigen-specific primary human NK cells against HER-2 positive carcinomas
- (2008) A. Kruschinski et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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