The Role of Fatty Acids in Non-Alcoholic Fatty Liver Disease Progression: An Update

Untargeted metabolomics as a diagnostic tool in NAFLD: discrimination of steatosis, steatohepatitis and cirrhosis

(2021) Mario Masarone et al.   Metabolomics

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2021) Hyuna Sung et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Non-alcoholic fatty liver disease in obese children and adolescents: a role for nutrition?

(2021) Luisa Bonsembiante et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Commentary: Anti-tumor Effect of Oleic Acid in Hepatocellular Carcinoma Cell Lines via Autophagy Reduction

(2021) Jiong Lin   Frontiers in Cell and Developmental Biology

Sodium butyrate supplementation inhibits hepatic steatosis by stimulating liver kinase B1 and insulin-induced gene

(2021) Ze-Hua Zhao et al.   Cellular and Molecular Gastroenterology and Hepatology

Rearrangements of Blood and Tissue Fatty Acid Profile in Colorectal Cancer - Molecular Mechanism and Diagnostic Potential

(2021) Adriana Mika et al.   Frontiers in Oncology

Biological Role of Unsaturated Fatty Acid Desaturases in Health and Disease

(2020) Aleksandra Czumaj et al.   Nutrients

The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Communication

(2020) Ygor Parladore Silva et al.   Frontiers in Endocrinology

Advances in non-invasive biomarkers for the diagnosis and monitoring of non-alcoholic fatty liver disease

(2020) Michelle T. Long et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Understanding lipotoxicity in NAFLD pathogenesis: is CD36 a key driver?

(2020) Patricia Rada et al.   Cell Death & Disease

Non-Alcoholic Steatohepatitis: A Review of Its Mechanism, Models and Medical Treatments

(2020) Cheng Peng et al.   Frontiers in Pharmacology

Remodeling Lipids in the Transition from Chronic Liver Disease to Hepatocellular Carcinoma

(2020) Israa T. Ismail et al.   Cancers

The Role of Mitochondrial Fat Oxidation in Cancer Cell Proliferation and Survival

(2020) Matheus Pinto De Oliveira et al.   Cells

Metabolic alterations and vulnerabilities in hepatocellular carcinoma

(2020) Daniel G Tenen et al.   Gastroenterology Report

Alterations of Fatty Acid Profile May Contribute to Dyslipidemia in Chronic Kidney Disease by Influencing Hepatocyte Metabolism

(2019) Aleksandra Czumaj et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Dietary butyrate suppresses inflammation through modulating gut microbiota in high-fat diet-fed mice

(2019) Shixiang Zhai et al.   FEMS MICROBIOLOGY LETTERS

Ultrasound-based techniques for the diagnosis of liver steatosis

(2019) Giovanna Ferraioli et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Dietary short-chain fatty acid intake improves the hepatic metabolic condition via FFAR3

(2019) Hidenori Shimizu et al.   Scientific Reports

Acetyl-CoA Carboxylase Inhibitor GS-0976 for 12 Weeks Reduces Hepatic De Novo Lipogenesis and Steatosis in Patients With Nonalcoholic Steatohepatitis

(2018) Eric J. Lawitz et al.   Clinical Gastroenterology and Hepatology

Bioactive Lipid Species and Metabolic Pathways in Progression and Resolution of Nonalcoholic Steatohepatitis

(2018) Giovanni Musso et al.   GASTROENTEROLOGY

Acetyl-CoA Carboxylase Inhibition Reverses NAFLD and Hepatic Insulin Resistance but Promotes Hypertriglyceridemia in Rodents

(2018) Leigh Goedeke et al.   HEPATOLOGY

A randomized, placebo-controlled trial of cenicriviroc for treatment of nonalcoholic steatohepatitis with fibrosis

(2018) Scott L. Friedman et al.   HEPATOLOGY

Cyclopropaneoctanoic Acid 2-Hexyl Upregulates the Expression of Genes Responsible for Lipid Synthesis and Release in Human Hepatic HepG2 Cells

(2018) Aleksandra Czumaj et al.   LIPIDS

Noninvasive biomarkers in NAFLD and NASH — current progress and future promise

(2018) Vincent Wai-Sun Wong et al.   Nature Reviews Gastroenterology & Hepatology

GS-0976 Reduces Hepatic Steatosis and Fibrosis Markers in Patients With Nonalcoholic Fatty Liver Disease

(2018) Rohit Loomba et al.   GASTROENTEROLOGY

Non-alcoholic fatty liver disease – A global public health perspective

(2018) Zobair M. Younossi   JOURNAL OF HEPATOLOGY

Lipid Metabolic Reprogramming in Hepatocellular Carcinoma

(2018) Hayato Nakagawa et al.   Cancers

Functional lipidomics: Palmitic acid impairs hepatocellular carcinoma development by modulating membrane fluidity and glucose metabolism

(2017) Ling Lin et al.   HEPATOLOGY

Free fatty acids profile among lean, overweight and obese non-alcoholic fatty liver disease patients: a case – control study

(2017) Rennan Feng et al.   Lipids in Health and Disease

Sodium butyrate attenuates high-fat diet-induced steatohepatitis in mice by improving gut microbiota and gastrointestinal barrier

(2017) Da Zhou et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Metabolism dysregulation induces a specific lipid signature of nonalcoholic steatohepatitis in patients

(2017) Franck Chiappini et al.   Scientific Reports

From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites

(2016) Ara Koh et al.   CELL

Noninvasive Detection of Nonalcoholic Steatohepatitis Using Clinical Markers and Circulating Levels of Lipids and Metabolites

(2016) You Zhou et al.   Clinical Gastroenterology and Hepatology

The severity of nonalcoholic fatty liver disease is associated with gut dysbiosis and shift in the metabolic function of the gut microbiota

(2016) Jérôme Boursier et al.   HEPATOLOGY

Molecular mechanisms of lipotoxicity and glucotoxicity in nonalcoholic fatty liver disease

(2016) Manoela Mota et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Nonalcoholic fatty liver disease and hepatocellular carcinoma

(2016) Heinz Zoller et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Importance of propionate for the repression of hepatic lipogenesis and improvement of insulin sensitivity in high-fat diet-induced obesity

(2016) Karolin Weitkunat et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Longitudinal metabolic imaging of hepatocellular carcinoma in transgenic mouse models identifies acylcarnitine as a potential biomarker for early detection

(2016) Jadegoud Yaligar et al.   Scientific Reports

Serum lipidomic profiling as a useful tool for screening potential biomarkers of hepatitis B-related hepatocellular carcinoma by ultraperformance liquid chromatography–mass spectrometry

(2015) Ana Maria Passos-Castilho et al.   BMC CANCER

Short-Chain Fatty Acids Protect Against High-Fat Diet–Induced Obesity via a PPARγ-Dependent Switch From Lipogenesis to Fat Oxidation

(2015) Gijs den Besten et al.   DIABETES

Functional Roles of Fatty Acids and Their Effects on Human Health

(2015) Philip C. Calder   JOURNAL OF PARENTERAL AND ENTERAL NUTRITION

Abnormalities in Plasma Phospholipid Fatty Acid Profiles of Patients with Hepatocellular Carcinoma

(2015) Jian-Feng Qiu et al.   LIPIDS

Role of bioactive fatty acids in nonalcoholic fatty liver disease

(2015) Eva Juárez-Hernández et al.   Nutrition Journal

Liver cirrhosis

(2014) Emmanuel A Tsochatzis et al.   LANCET

Characteristics of hepatic fatty acid compositions in patients with nonalcoholic steatohepatitis

(2014) Kazutoshi Yamada et al.   LIVER INTERNATIONAL

Gut-derived short-chain fatty acids are vividly assimilated into host carbohydrates and lipids

(2013) Gijs den Besten et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Intestinal microbiota in patients with nonalcoholic fatty liver disease

(2013) Marialena Mouzaki et al.   HEPATOLOGY

A gene variant ofPNPLA3, but not ofAPOC3, is associated with histological parameters of NAFLD in an obese population

(2013) A. Verrijken et al.   Obesity

Serum metabolomics reveals the deregulation of fatty acids metabolism in hepatocellular carcinoma and chronic liver diseases

(2012) Lina Zhou et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Intrahepatic Diacylglycerol Content Is Associated With Hepatic Insulin Resistance in Obese Subjects

(2012) Faidon Magkos et al.   GASTROENTEROLOGY

The diagnosis and management of non-alcoholic fatty liver disease: Practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association

(2012) Naga Chalasani et al.   HEPATOLOGY

Characterization of gut microbiomes in nonalcoholic steatohepatitis (NASH) patients: A connection between endogenous alcohol and NASH

(2012) Lixin Zhu et al.   HEPATOLOGY

Role of patatin-like phospholipase domain-containing 3 on lipid-induced hepatic steatosis and insulin resistance in rats

(2012) Naoki Kumashiro et al.   HEPATOLOGY

Resistance training restores the gene expression of molecules related to fat oxidation and lipogenesis in the liver of ovariectomized rats

(2011) Mateus Moraes Domingos et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Genetic factors associated with the presence and progression of nonalcoholic fatty liver disease: A narrative review

(2011) Ruben Hernaez   Gastroenterologia y Hepatologia

Liver fatty acid composition in mice with or without nonalcoholic fatty liver disease

(2011) Xin Wang et al.   Lipids in Health and Disease

Linking endoplasmic reticulum stress to cell death in hepatocytes: roles of C/EBP homologous protein and chemical chaperones in palmitate-mediated cell death

(2010) Kyle T. Pfaffenbach et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Long-chain saturated fatty acids induce pro-inflammatory responses and impact endothelial cell growth

(2009) Kevin A. Harvey et al.   CLINICAL NUTRITION

The plasma lipidomic signature of nonalcoholic steatohepatitis

(2009) Puneet Puri et al.   HEPATOLOGY

Stearoyl-Coenzyme A Desaturase 1 Gene Expression Increases after Pioglitazone Treatment and Is Associated with Peroxisomal Proliferator-Activated Receptor-γ Responsiveness

(2008) Aiwei Yao-Borengasser et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The Epidemiology of Nonalcoholic Fatty Liver Disease: A Global Perspective

(2008) Mariana Lazo et al.   SEMINARS IN LIVER DISEASE