Clemastine attenuates AD-like pathology in an AD model mouse via enhancing mTOR-mediated autophagy
出版年份 2021 全文链接
标题
Clemastine attenuates AD-like pathology in an AD model mouse via enhancing mTOR-mediated autophagy
作者
关键词
Clemastine, Autophagy, mTOR, Alzheimer's disease, Neurodegenerative disease
出版物
EXPERIMENTAL NEUROLOGY
Volume 342, Issue -, Pages 113742
出版商
Elsevier BV
发表日期
2021-05-07
DOI
10.1016/j.expneurol.2021.113742
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Multifarious roles of mTOR signaling in cognitive aging and cerebrovascular dysfunction of Alzheimer's disease
- (2020) Md. Sahab Uddin et al. IUBMB LIFE
- Molecular Mechanisms of ER Stress and UPR in the Pathogenesis of Alzheimer’s Disease
- (2020) Md. Sahab Uddin et al. MOLECULAR NEUROBIOLOGY
- Revisiting the role of brain and peripheral Aβ in the pathogenesis of Alzheimer's disease
- (2020) Md. Sahab Uddin et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Resveratrol and Neuroprotection: Impact and Its Therapeutic Potential in Alzheimer's Disease
- (2020) Md. Habibur Rahman et al. Frontiers in Pharmacology
- Targeting Autophagy for the Treatment of Alzheimer’s Disease: Challenges and Opportunities
- (2019) Jie Liu et al. Frontiers in Molecular Neuroscience
- Astrocytes autophagy in aging and neurodegenerative disorders
- (2019) Jun-Ling Wang et al. BIOMEDICINE & PHARMACOTHERAPY
- Absence of TRIM32 Leads to Reduced GABAergic Interneuron Generation and Autism-like Behaviors in Mice via Suppressing mTOR Signaling
- (2019) Jian-Wei Zhu et al. CEREBRAL CORTEX
- Progesterone suppresses Aβ 42 -induced neuroinflammation by enhancing autophagy in astrocytes
- (2018) Yang Hong et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- APOE and Alzheimer’s Disease: Evidence Mounts that Targeting APOE4 may Combat Alzheimer’s Pathogenesis
- (2018) Md. Sahab Uddin et al. MOLECULAR NEUROBIOLOGY
- Autophagy and Alzheimer’s Disease: From Molecular Mechanisms to Therapeutic Implications
- (2018) Md. Sahab Uddin et al. Frontiers in Aging Neuroscience
- Inhibition of sphingomyelin synthase 1 ameliorates alzheimer-like pathology in APP/PS1 transgenic mice through promoting lysosomal degradation of BACE1
- (2018) Mei-Hong Lu et al. EXPERIMENTAL NEUROLOGY
- Clemastine Alleviates Depressive-Like Behavior Through Reversing the Imbalance of Microglia-Related Pro-inflammatory State in Mouse Hippocampus
- (2018) Wen-Jun Su et al. Frontiers in Cellular Neuroscience
- Clemastine fumarate as a remyelinating therapy for multiple sclerosis (ReBUILD): a randomised, controlled, double-blind, crossover trial
- (2017) Ari J Green et al. LANCET
- Astemizole–Histamine induces Beclin-1-independent autophagy by targeting p53-dependent crosstalk between autophagy and apoptosis
- (2016) Rekha Jakhar et al. CANCER LETTERS
- Clemastine Enhances Myelination in the Prefrontal Cortex and Rescues Behavioral Changes in Socially Isolated Mice
- (2016) J. Liu et al. JOURNAL OF NEUROSCIENCE
- Inhibiting BACE1 to reverse synaptic dysfunctions in Alzheimer’s disease
- (2016) Riqiang Yan et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Stepping closer to treating Alzheimer’s disease patients with BACE1 inhibitor drugs
- (2016) Riqiang Yan Translational Neurodegeneration
- Involvement of inflammation in Alzheimer’s disease pathogenesis and therapeutic potential of anti-inflammatory agents
- (2015) Sina Shadfar et al. ARCHIVES OF PHARMACAL RESEARCH
- Three dimensions of the amyloid hypothesis: time, space and 'wingmen'
- (2015) Erik S Musiek et al. NATURE NEUROSCIENCE
- Disrupted-in-Schizophrenia-1 Attenuates Amyloid-β Generation and Cognitive Deficits in APP/PS1 Transgenic Mice by Reduction of β-Site APP-Cleaving Enzyme 1 Levels
- (2015) Qing-Shan Deng et al. NEUROPSYCHOPHARMACOLOGY
- Clemastine rescues behavioral changes and enhances remyelination in the cuprizone mouse model of demyelination
- (2015) Zhifang Li et al. Neuroscience Bulletin
- Autophagy in microglia degrades extracellular β-amyloid fibrils and regulates the NLRP3 inflammasome
- (2014) Mi-Hyang Cho et al. Autophagy
- Clemastine Confers Neuroprotection and Induces an Anti-Inflammatory Phenotype in SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis
- (2014) Savina Apolloni et al. MOLECULAR NEUROBIOLOGY
- Lamotrigine attenuates deficits in synaptic plasticity and accumulation of amyloid plaques in APP/PS1 transgenic mice
- (2014) Mao-Ying Zhang et al. NEUROBIOLOGY OF AGING
- Latrepirdine (Dimebon®), a potential Alzheimer therapeutic, regulates autophagy and neuropathology in an Alzheimer mouse model
- (2013) John W. Steele et al. Autophagy
- The role of autophagy in neurodegenerative disease
- (2013) Ralph A Nixon NATURE MEDICINE
- Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer's APP-CTF for terminal degradation via autophagy
- (2013) Y. Tian et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Neuronal autophagy and neurodegenerative diseases
- (2012) Jin H. Son et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- H1-antihistamines induce vacuolation in astrocytes through macroautophagy
- (2012) Wei-Wei Hu et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
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