Metabolic fate of docosahexaenoic acid (DHA; 22:6n-3) in human cells: direct retroconversion of DHA to eicosapentaenoic acid (20:5n-3) dominates over elongation to tetracosahexaenoic acid (24:6n-3)

Efficacy of omega-3 highly unsaturated fatty acids in the treatment of depression

(2016) Brian Hallahan et al.   BRITISH JOURNAL OF PSYCHIATRY

The fatty acid desaturase 2 (FADS2) gene product catalyzes Δ4 desaturation to yield n-3 docosahexaenoic acid and n-6 docosapentaenoic acid in human cells

(2015) Hui Gyu Park et al.   FASEB JOURNAL

β-oxidation and rapid metabolism, but not uptake regulate brain eicosapentaenoic acid levels

(2015) Chuck T. Chen et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Mitochondrial NADP(H) deficiency due to a mutation in NADK2 causes dienoyl-CoA reductase deficiency with hyperlysinemia

(2014) Sander M. Houten et al.   HUMAN MOLECULAR GENETICS

Retroconversion of Docosapentaenoic Acid (n-6): an Alternative Pathway for Biosynthesis of Arachidonic Acid in Daphnia magna

(2014) Ursula Strandberg et al.   LIPIDS

Marine polyunsaturated fatty acids and cancer therapy

(2013) V C Vaughan et al.   BRITISH JOURNAL OF CANCER

Incorporation of eicosapentaenoic and docosahexaenoic acids into lipid pools when given as supplements providing doses equivalent to typical intakes of oily fish

(2012) Lucy M Browning et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Functional redundancy of mitochondrial enoyl-CoA isomerases in the oxidation of unsaturated fatty acids

(2012) Michel van Weeghel et al.   FASEB JOURNAL

Carnitine palmitoyltransferase 1A prevents fatty acid-induced adipocyte dysfunction through suppression of c-Jun N-terminal kinase

(2011) Xuefei Gao et al.   BIOCHEMICAL JOURNAL

Establishing a relationship between prolactin and altered fatty acid β-Oxidation via carnitine palmitoyl transferase 1 in breast cancer cells

(2011) Katja Linher-Melville et al.   BMC CANCER

Identification of ACOX2 as a shared genetic risk factor for preeclampsia and cardiovascular disease

(2011) Åsa Johansson et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

DHA and EPA reverse cystic fibrosis-related FA abnormalities by suppressing FA desaturase expression and activity

(2011) Sarah W. Njoroge et al.   JOURNAL OF LIPID RESEARCH

Plasma incorporation, apparent retroconversion and β-oxidation of 13C-docosahexaenoic acid in the elderly

(2011) Mélanie Plourde et al.   Nutrition & Metabolism

Docosahexaenoic Acid Is Essential to Development of Critical Functions in Infants

(2010) Michael Thomas Clandinin et al.   JOURNAL OF PEDIATRICS

Functional significance of the two ACOX1 isoforms and their crosstalks with PPARα and RXRα

(2010) Aurore Vluggens et al.   LABORATORY INVESTIGATION

Rapid β-oxidation of eicosapentaenoic acid in mouse brain: An in situ study

(2009) Chuck T. Chen et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

The Metabolism and Distribution of Docosapentaenoic Acid (n-6) in the Liver and Testis of Growing Rats

(2008) Phyllis S. Y. TAM et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Lipid, sterols and fatty acid composition of abyssal holothurians and ophiuroids from the North-East Pacific Ocean: Food web implications

(2008) Jeffrey C. Drazen et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY

Effect of n-3 polyunsaturated fatty acids in patients with chronic heart failure (the GISSI-HF trial): a randomised, double-blind, placebo-controlled trial

(2008) GISSI-HF investigators   LANCET