Getting from A to B—exploring the activation motifs of the class B adhesion G protein-coupled receptor subfamily G member 4/GPR112

Functional elements of the gastric inhibitory polypeptide receptor: Comparison between secretin- and rhodopsin-like G protein-coupled receptors

(2015) Arnau Cordomí et al.   BIOCHEMICAL PHARMACOLOGY

Adhesion G protein-coupled receptors are activated by exposure of a cryptic tethered agonist

(2015) Hannah M. Stoveken et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generic GPCR residue numbers – aligning topology maps while minding the gaps

(2015) Vignir Isberg et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Domains for activation and inactivation in G protein-coupled receptors – A mutational analysis of constitutive activity of the adenosine A2B receptor

(2014) Miriam C. Peeters et al.   BIOCHEMICAL PHARMACOLOGY

A Tethered Agonist within the Ectodomain Activates the Adhesion G Protein-Coupled Receptors GPR126 and GPR133

(2014) Ines Liebscher et al.   Cell Reports

Meet the B family

(2013) Patrick M. Sexton et al.   NATURE

Structure of class B GPCR corticotropin-releasing factor receptor 1

(2013) Kaspar Hollenstein et al.   NATURE

Structure of the human glucagon class B G-protein-coupled receptor

(2013) Fai Yiu Siu et al.   NATURE

Molecular signatures of G-protein-coupled receptors

(2013) A. J. Venkatakrishnan et al.   NATURE

GPCRDB: an information system for G protein-coupled receptors

(2013) Vignir Isberg et al.   NUCLEIC ACIDS RESEARCH

Polar transmembrane interactions drive formation of ligand-specific and signal pathway-biased family B G protein-coupled receptor conformations

(2013) D. Wootten et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dissecting signaling and functions of adhesion G protein-coupled receptors

(2012) Demet Araç et al.   Annals of the New York Academy of Sciences

Similarity between class A and class B G-protein-coupled receptors exemplified through calcitonin gene-related peptide receptor modelling and mutagenesis studies

(2012) S. Vohra et al.   Journal of the Royal Society Interface

The Origin of GPCRs: Identification of Mammalian like Rhodopsin, Adhesion, Glutamate and Frizzled GPCRs in Fungi

(2012) Arunkumar Krishnan et al.   PLoS One

Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions

(2012) W. Liu et al.   SCIENCE

LPA Receptor Heterodimerizes with CD97 to Amplify LPA-Initiated RHO-Dependent Signaling and Invasion in Prostate Cancer Cells

(2011) Y. Ward et al.   CANCER RESEARCH

The N Terminus of the Adhesion G Protein-coupled Receptor GPR56 Controls Receptor Signaling Activity

(2011) Kevin J. Paavola et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Residues within the Transmembrane Domain of the Glucagon-Like Peptide-1 Receptor Involved in Ligand Binding and Receptor Activation: Modelling the Ligand-Bound Receptor

(2011) K. Coopman et al.   MOLECULAR ENDOCRINOLOGY

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology

Three “hotspots” important for adenosine A2B receptor activation: a mutational analysis of transmembrane domains 4 and 5 and the second extracellular loop

(2011) Miriam C. Peeters et al.   Purinergic Signalling

Brain-specific angiogenesis inhibitor 2 (BAI2) may be activated by proteolytic processing

(2010) Daisuke Okajima et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Evidence that Interaction between Conserved Residues in Transmembrane Helices 2, 3, and 7 Are Crucial for Human VPAC1 Receptor Activation

(2010) A. O. Chugunov et al.   MOLECULAR PHARMACOLOGY

An efficient one-step site-directed deletion, insertion, single and multiple-site plasmid mutagenesis protocol

(2009) Huanting Liu et al.   BMC BIOTECHNOLOGY

The Secretin GPCRs Descended from the Family of Adhesion GPCRs

(2008) K. J. V. Nordstrom et al.   MOLECULAR BIOLOGY AND EVOLUTION

Structure of a β1-adrenergic G-protein-coupled receptor

(2008) Tony Warne et al.   NATURE

Membrane lipids: where they are and how they behave

(2008) Gerrit van Meer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A Specific Cholesterol Binding Site Is Established by the 2.8 Å Structure of the Human β2-Adrenergic Receptor

(2008) Michael A. Hanson et al.   STRUCTURE

New G-protein-coupled receptor crystal structures: insights and limitations

(2008) B KOBILKA et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

G Protein Coupled Receptors as Drug Targets: The Role of β-Arrestins

(2008) Jasmin Dromey et al.   Endocrine Metabolic & Immune Disorders-Drug Targets