The phospholipase A2 activity of peroxiredoxin 6 modulates NADPH oxidase 2 activation via lysophosphatidic acid receptor signaling in the pulmonary endothelium and alveolar macrophages

Critical role of peroxiredoxin 6 in the repair of peroxidized cell membranes following oxidative stress

(2015) Haitao Li et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inhibition of the phospholipase A2 activity of peroxiredoxin 6 prevents lung damage with exposure to hyperoxia

(2015) Bavneet Benipal et al.   Redox Biology

Protection against LPS-induced acute lung injury by a mechanism-based inhibitor of NADPH oxidase (type 2)

(2014) Intae Lee et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Endothelial Cell–Specific Reactive Oxygen Species Production Increases Susceptibility to Aortic Dissection

(2014) Lampson M. Fan et al.   CIRCULATION

Nox family NADPH oxidases: Molecular mechanisms of activation

(2014) Ralf P. Brandes et al.   FREE RADICAL BIOLOGY AND MEDICINE

Endosomal H2O2 production leads to localized cysteine sulfenic acid formation on proteins during lysophosphatidic acid-mediated cell signaling

(2014) Chananat Klomsiri et al.   FREE RADICAL BIOLOGY AND MEDICINE

Arachidonic Acid Induces Direct Interaction of the p67phox-Rac Complex with the Phagocyte Oxidase Nox2, Leading to Superoxide Production

(2014) Rumi Matono et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LPA receptor signaling: pharmacology, physiology, and pathophysiology

(2014) Yun C. Yung et al.   JOURNAL OF LIPID RESEARCH

Lysophosphatidic acid induces integrin activation in vascular smooth muscle and alters arteriolar myogenic vasoconstriction

(2014) Marius C. Staiculescu et al.   Frontiers in Physiology

Possible Role of Lysophosphatidic Acid in Rat Model of Hypoxic Pulmonary Vascular Remodeling

(2014) Vadim Shlyonsky et al.   Pulmonary Circulation

Nox2-Induced Production of Mitochondrial Superoxide in Angiotensin II-Mediated Endothelial Oxidative Stress and Hypertension

(2013) Sergey I. Dikalov et al.   ANTIOXIDANTS & REDOX SIGNALING

NADPH Oxidases in Lung Health and Disease

(2013) Karen Bernard et al.   ANTIOXIDANTS & REDOX SIGNALING

Pulmonary Endothelial Cell NOX

(2012) Rachel Damico et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Lysophosphatidic acid causes endothelial dysfunction in porcine coronary arteries and human coronary artery endothelial cells

(2012) Chanygi Chen et al.   ATHEROSCLEROSIS

Lysoglycerophospholipids in chronic inflammatory disorders: The PLA2/LPC and ATX/LPA axes

(2012) Ioanna Sevastou et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Peroxiredoxin 6 translocates to the plasma membrane during neutrophil activation and is required for optimal NADPH oxidase activity

(2011) Daniel R. Ambruso et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Peroxiredoxin 6 Phosphorylation and Subsequent Phospholipase A2Activity Are Required for Agonist-mediated Activation of NADPH Oxidase in Mouse Pulmonary Microvascular Endothelium and Alveolar Macrophages

(2011) Shampa Chatterjee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insights into autotaxin: how to produce and present a lipid mediator

(2011) Wouter H. Moolenaar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A novel, orally active LPA1 receptor antagonist inhibits lung fibrosis in the mouse bleomycin model

(2010) JS Swaney et al.   BRITISH JOURNAL OF PHARMACOLOGY

Comparison of glutathione peroxidase 1 and peroxiredoxin 6 in protection against oxidative stress in the mouse lung

(2010) Geng Liu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Boronic acid-based inhibitor of autotaxin reveals rapid turnover of LPA in the circulation

(2010) H. M. H. G. Albers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitogen-activated protein kinase-mediated phosphorylation of peroxiredoxin 6 regulates its phospholipase A2activity

(2009) Yongzheng Wu et al.   BIOCHEMICAL JOURNAL

Role of acylglycerol kinase in LPA-induced IL-8 secretion and transactivation of epidermal growth factor-receptor in human bronchial epithelial cells

(2008) Satish Kalari et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Phospholipase A2structure/function, mechanism, and signaling

(2008) John E. Burke et al.   JOURNAL OF LIPID RESEARCH

Role of LPA4/p2y9/GPR23 in Negative Regulation of Cell Motility

(2008) Zendra Lee et al.   MOLECULAR BIOLOGY OF THE CELL

Composition and Functions of Vascular Nicotinamide Adenine Dinucleotide Phosphate Oxidases

(2008) Ralf P. Brandes et al.   TRENDS IN CARDIOVASCULAR MEDICINE