标题
Cellular mechanisms of mtDNA heteroplasmy dynamics
作者
关键词
-
出版物
CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
Volume 56, Issue 5, Pages 510-525
出版商
Informa UK Limited
发表日期
2021-06-14
DOI
10.1080/10409238.2021.1934812
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- A Naturally Heteroplasmic Clam Provides Clues about the Effects of Genetic Bottleneck on Paternal mtDNA
- (2021) Mariangela Iannello et al. Genome Biology and Evolution
- Mitochondrial DNA editing in mice with DddA-TALE fusion deaminases
- (2021) Hyunji Lee et al. Nature Communications
- Environmental factors for establishment of the dormant state in oocytes
- (2020) Katsuhiko Hayashi et al. DEVELOPMENT GROWTH & DIFFERENTIATION
- Mitochondrial fission and fusion: A dynamic role in aging and potential target for age-related disease
- (2020) Yasmine J. Liu et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Coordinating Proliferation, Polarity, and Cell Fate in the Drosophila Female Germline
- (2020) Taylor D. Hinnant et al. Frontiers in Cell and Developmental Biology
- Therapeutic Manipulation of mtDNA Heteroplasmy: A Shifting Perspective
- (2020) Christopher B. Jackson et al. TRENDS IN MOLECULAR MEDICINE
- Mitophagy: An Emerging Role in Aging and Age-Associated Diseases
- (2020) Guo Chen et al. Frontiers in Cell and Developmental Biology
- A bacterial cytidine deaminase toxin enables CRISPR-free mitochondrial base editing
- (2020) Beverly Y. Mok et al. NATURE
- Purifying Selection against Pathogenic Mitochondrial DNA in Human T Cells
- (2020) Melissa A. Walker et al. NEW ENGLAND JOURNAL OF MEDICINE
- Cell identity and nucleo-mitochondrial genetic context modulate OXPHOS performance and determine somatic heteroplasmy dynamics
- (2020) Ana Victoria Lechuga-Vieco et al. Science Advances
- Visualizing, quantifying and manipulating mitochondrial DNA in vivo.
- (2020) David L Prole et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Nutrient status shapes selfish mitochondrial genome dynamics across different levels of selection
- (2020) Bryan L Gitschlag et al. eLife
- PINK1 Inhibits Local Protein Synthesis to Limit Transmission of Deleterious Mitochondrial DNA Mutations
- (2019) Yi Zhang et al. MOLECULAR CELL
- Mitochondrial fragmentation drives selective removal of deleterious mtDNA in the germline
- (2019) Toby Lieber et al. NATURE
- Germline selection shapes human mitochondrial DNA diversity
- (2019) Wei Wei et al. SCIENCE
- Reversion after replacement of mitochondrial DNA
- (2019) Gavin Hudson et al. NATURE
- Regulation of Mother-to-Offspring Transmission of mtDNA Heteroplasmy
- (2019) Ana Latorre-Pellicer et al. Cell Metabolism
- A Genome-wide Screen Reveals that Reducing Mitochondrial DNA Polymerase Can Promote Elimination of Deleterious Mitochondrial Mutations
- (2019) Ason C.-Y. Chiang et al. CURRENT BIOLOGY
- Intracellular quality control of mitochondrial DNA: evidence and limitations
- (2019) Dmitry A. Knorre PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Faraway, so close. The comparative method and the potential of non-model animals in mitochondrial research
- (2019) Liliana Milani et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- The conflict within: origin, proliferation and persistence of a spontaneously arising selfish mitochondrial genome
- (2019) Joseph James Dubie et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Pronounced somatic bottleneck in mitochondrial DNA of human hair
- (2019) Alison Barrett et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- The mitochondrial DNA genetic bottleneck: inheritance and beyond
- (2018) Haixin Zhang et al. Essays in Biochemistry
- Mitochondrial DNA replication in mammalian cells: overview of the pathway
- (2018) Maria Falkenberg Essays in Biochemistry
- Segregation of mitochondrial DNA heteroplasmy through a developmental genetic bottleneck in human embryos
- (2018) Vasileios I. Floros et al. NATURE CELL BIOLOGY
- Affinity purification of cell-specific mitochondria from whole animals resolves patterns of genetic mosaicism
- (2018) Arnaud Ahier et al. NATURE CELL BIOLOGY
- Linear mitochondrial DNA is rapidly degraded by components of the replication machinery
- (2018) Viktoriya Peeva et al. Nature Communications
- The mitochondrial DNA polymerase gamma degrades linear DNA fragments precluding the formation of deletions
- (2018) Nadee Nissanka et al. Nature Communications
- Binucleate germ cells in Caenorhabditis elegans are removed by physiological apoptosis
- (2018) Stephan A. Raiders et al. PLoS Genetics
- MitoTALEN reduces mutant mtDNA load and restores tRNAAla levels in a mouse model of heteroplasmic mtDNA mutation
- (2018) Sandra R. Bacman et al. NATURE MEDICINE
- Genome editing in mitochondria corrects a pathogenic mtDNA mutation in vivo
- (2018) Payam A. Gammage et al. NATURE MEDICINE
- Clonal expansion of mtDNA deletions: different disease models assessed by digital droplet PCR in single muscle cells
- (2018) Selena Trifunov et al. Scientific Reports
- Current strategies towards therapeutic manipulation of mtDNA heteroplasmy
- (2017) Carlos T Moraes Frontiers in Bioscience-Landmark
- Mitochondrial energy generation disorders: genes, mechanisms and clues to pathology
- (2017) Ann E. Frazier et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Genetic Counselling for Maternally Inherited Mitochondrial Disorders
- (2017) Joanna Poulton et al. Molecular Diagnosis & Therapy
- The mitochondrial UPR: mechanisms, physiological functions and implications in ageing
- (2017) Tomer Shpilka et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- daf-16/FoxO promotes gluconeogenesis and trehalose synthesis during starvation to support survival
- (2017) Jonathan D Hibshman et al. eLife
- Characterization of the direct targets of FOXO transcription factors throughout evolution
- (2016) Ashley E. Webb et al. AGING CELL
- Expanding Our Understanding of mtDNA Deletions
- (2016) Martin Picard et al. Cell Metabolism
- Homeostatic Responses Regulate Selfish Mitochondrial Genome Dynamics in C. elegans
- (2016) Bryan L. Gitschlag et al. Cell Metabolism
- Genetic Drift Can Compromise Mitochondrial Replacement by Nuclear Transfer in Human Oocytes
- (2016) Mitsutoshi Yamada et al. Cell Stem Cell
- The mitochondrial outer membrane protein MDI promotes local protein synthesis and mtDNA replication
- (2016) Yi Zhang et al. EMBO JOURNAL
- The ageing neuromuscular system and sarcopenia: a mitochondrial perspective
- (2016) Karolina A. Rygiel et al. JOURNAL OF PHYSIOLOGY-LONDON
- Towards clinical application of pronuclear transfer to prevent mitochondrial DNA disease
- (2016) Louise A. Hyslop et al. NATURE
- Mitochondrial replacement in human oocytes carrying pathogenic mitochondrial DNA mutations
- (2016) Eunju Kang et al. NATURE
- Maintenance and propagation of a deleterious mitochondrial genome by the mitochondrial unfolded protein response
- (2016) Yi-Fan Lin et al. NATURE
- Selfish drive can trump function when animal mitochondrial genomes compete
- (2016) Hansong Ma et al. NATURE GENETICS
- Selective removal of deletion-bearing mitochondrial DNA in heteroplasmic Drosophila
- (2016) Nikolay P. Kandul et al. Nature Communications
- A Phenotype-Driven Approach to Generate Mouse Models with Pathogenic mtDNA Mutations Causing Mitochondrial Disease
- (2016) Johanna H.K. Kauppila et al. Cell Reports
- Mitochondrial diseases
- (2016) Gráinne S. Gorman et al. Nature Reviews Disease Primers
- Prevalence of nuclear and mitochondrial DNA mutations related to adult mitochondrial disease
- (2015) Gráinne S. Gorman et al. ANNALS OF NEUROLOGY
- Mitochondrial DNA: A disposable genome?
- (2015) Inna N. Shokolenko et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Selective Elimination of Mitochondrial Mutations in the Germline by Genome Editing
- (2015) Pradeep Reddy et al. CELL
- Quantitative Changes in Gimap3 and Gimap5 Expression Modify Mitochondrial DNA Segregation in Mice
- (2015) R. Jokinen et al. GENETICS
- Mitochondria: Biogenesis and mitophagy balance in segregation and clonal expansion of mitochondrial DNA mutations
- (2015) Valerio Carelli et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Parkin modulates heteroplasmy of truncated mtDNA in Caenorhabditis elegans
- (2015) Itay Valenci et al. MITOCHONDRION
- The dynamics of mitochondrial DNA heteroplasmy: implications for human health and disease
- (2015) James B. Stewart et al. NATURE REVIEWS GENETICS
- Extensive tissue-related and allele-related mtDNA heteroplasmy suggests positive selection for somatic mutations
- (2015) Mingkun Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Research into Policy: A Brief History of Mitochondrial Donation
- (2015) Lyndsey Craven et al. STEM CELLS
- UK is set to allow mitochondrial donation after MPs vote in favour
- (2015) C. Dyer BMJ-British Medical Journal
- UK is set to allow mitochondrial donation after MPs vote in favour
- (2015) C. Dyer BMJ-British Medical Journal
- Dissecting the mechanisms underlying the accumulation of mitochondrial DNA deletions in human skeletal muscle
- (2014) G. Campbell et al. HUMAN MOLECULAR GENETICS
- LC–MS Proteomics Analysis of the Insulin/IGF-1-Deficient Caenorhabditis elegans daf-2(e1370) Mutant Reveals Extensive Restructuring of Intermediary Metabolism
- (2014) Geert Depuydt et al. JOURNAL OF PROTEOME RESEARCH
- Selective propagation of functional mitochondrial DNA during oogenesis restricts the transmission of a deleterious mitochondrial variant
- (2014) Jahda H Hill et al. NATURE GENETICS
- Transmission of mitochondrial mutations and action of purifying selection in Drosophila melanogaster
- (2014) Hansong Ma et al. NATURE GENETICS
- mtDNA Segregation in Heteroplasmic Tissues Is Common In Vivo and Modulated by Haplotype Differences and Developmental Stage
- (2014) Joerg Patrick Burgstaller et al. Cell Reports
- Clonal Expansion of Early to Mid-Life Mitochondrial DNA Point Mutations Drives Mitochondrial Dysfunction during Human Ageing
- (2014) Laura C. Greaves et al. PLoS Genetics
- PQM-1 Complements DAF-16 as a Key Transcriptional Regulator of DAF-2-Mediated Development and Longevity
- (2013) Ronald G. Tepper et al. CELL
- Mitochondrial DNA Genetics and the Heteroplasmy Conundrum in Evolution and Disease
- (2013) D. C. Wallace et al. Cold Spring Harbor Perspectives in Biology
- Recurrent Tissue-Specific mtDNA Mutations Are Common in Humans
- (2013) David C. Samuels et al. PLoS Genetics
- Towards germline gene therapy of inherited mitochondrial diseases
- (2012) Masahito Tachibana et al. NATURE
- Variation in germline mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission
- (2012) Christoph Freyer et al. NATURE GENETICS
- Selfish Little Circles: Transmission Bias and Evolution of Large Deletion-Bearing Mitochondrial DNA in Caenorhabditis briggsae Nematodes
- (2012) Katie A. Clark et al. PLoS One
- Experimental evidence showing that no mitotically active female germline progenitors exist in postnatal mouse ovaries
- (2012) H. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mitochondrial Import Efficiency of ATFS-1 Regulates Mitochondrial UPR Activation
- (2012) A. M. Nargund et al. SCIENCE
- Natural variation in life history and aging phenotypes is associated with mitochondrial DNA deletion frequency in Caenorhabditis briggsae
- (2011) Suzanne Estes et al. BMC EVOLUTIONARY BIOLOGY
- Mitochondrial autophagy in cells with mtDNA mutations results from synergistic loss of transmembrane potential and mTORC1 inhibition
- (2011) Robert W. Gilkerson et al. HUMAN MOLECULAR GENETICS
- Evolution Meets Disease: Penetrance and Functional Epistasis of Mitochondrial tRNA Mutations
- (2011) Raquel Moreno-Loshuertos et al. PLoS Genetics
- The Mitochondrial Proteome and Human Disease
- (2010) Sarah E. Calvo et al. Annual Review of Genomics and Human Genetics
- Parkin overexpression selects against a deleterious mtDNA mutation in heteroplasmic cybrid cells
- (2010) D.-F. Suen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Gimap3 Regulates Tissue-Specific Mitochondrial DNA Segregation
- (2010) Riikka Jokinen et al. PLoS Genetics
- Mitochondrial DNA mutations and human disease
- (2009) Helen A.L. Tuppen et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Inhibition of mitochondrial fission favours mutant over wild-type mitochondrial DNA
- (2009) Adriana Malena et al. HUMAN MOLECULAR GENETICS
- Mitochondrial DNA level, but not active replicase, is essential for Caenorhabditis elegans development
- (2009) Ivana Bratic et al. NUCLEIC ACIDS RESEARCH
- foxo is required for resistance to amino acid starvation in Drosophila
- (2008) Jamie M. Kramer et al. GENOME
- Purifying selection of mtDNA and its implications for understanding evolution and mitochondrial disease
- (2008) James Bruce Stewart et al. NATURE REVIEWS GENETICS
- A Mouse Model of Mitochondrial Disease Reveals Germline Selection Against Severe mtDNA Mutations
- (2008) Weiwei Fan et al. SCIENCE
- Strong Purifying Selection in Transmission of Mammalian Mitochondrial DNA
- (2008) James Bruce Stewart et al. PLOS BIOLOGY
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