4.7 Review

Computer simulation of submicron fluid flows in microfluidic chips and their applications in food analysis

期刊

出版社

WILEY
DOI: 10.1111/1541-4337.12766

关键词

driving modes; food analysis; food products; microfluidic chip; simulation

资金

  1. National Key R&D Program of China [2018YFC1603400]
  2. Guangdong Basic and Applied Basic Research Foundation [2020A1515010936]
  3. Fundamental Research Funds for the Central Universities [D2190450]
  4. Contemporary International Collaborative Research Centre of Guangdong Province on Food Innovative Processing and Intelligent Control [2019A050519001]
  5. Common Technical Innovation Team of Guangdong Province on Preservation and Logistics of Agricultural Products [2020KJ145]

向作者/读者索取更多资源

In recent years, microfluidics technology has gained attention for its application in food analysis, ensuring better detection and analysis efficiency through various submicron fluid driving methods, numerical simulations, and traditional methods. The high sensitivity, high throughput, portable, and integrated microfluidic chips development will enable the practical application of this technology, reflecting the specific, multifunctional, and sensitive detection and analysis capability for food products in the market.
In recent years, countries around the world have maintained a zero-tolerance attitude toward safety problems in the food industry. In order to ensure human health, a fast, sensitive, and high-throughput analysis of food contaminants is necessary to ensure safe food products on the market. Microfluidics, as a high-efficiency and sensitive detection technology, has many advantages in the detection of food contaminants, including foodborne pathogens, pesticides, heavy metal ions, toxic substances, and so forth, especially in conjunction with a variety of submicron fluid driving methods, making food detection and analysis more efficient and accurate. This review introduces the principle of submicron fluid driving modes and discusses the driving simulation of submicron fluid in microfluidic chips. In addition, the latest developments in the application of simulation in food analysis from 2006 to 2020 are discussed, and the computer simulation of submicron fluid flow in microfluidic chips and its application and development trend in food analysis are also highlighted. The review indicates that microfluidic technology, using numerical simulation as an auxiliary tool, combined with traditional methods has greatly improved the detection and analysis of food products. In addition, microfluidics combined with a variety of control methods embodies the ability of specific, multifunctional, and sensitive detection and analysis of food products. The development of high-sensitivity, high-throughput, portable, integrated microfluidic chips will enable the technology to be applied in practice.

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