标题
MERS-CoV spike protein: a key target for antivirals
作者
关键词
-
出版物
EXPERT OPINION ON THERAPEUTIC TARGETS
Volume 21, Issue 2, Pages 131-143
出版商
Informa UK Limited
发表日期
2016-12-19
DOI
10.1080/14728222.2017.1271415
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Single-dose treatment with a humanized neutralizing antibody affords full protection of a human transgenic mouse model from lethal Middle East respiratory syndrome (MERS)-coronavirus infection
- (2016) Hongjie Qiu et al. ANTIVIRAL RESEARCH
- Glycopeptide Antibiotics Potently Inhibit Cathepsin L in the Late Endosome/Lysosome and Block the Entry of Ebola Virus, Middle East Respiratory Syndrome Coronavirus (MERS-CoV), and Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)
- (2016) Nan Zhou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Prophylaxis With a Middle East Respiratory Syndrome Coronavirus (MERS-CoV)–Specific Human Monoclonal Antibody Protects Rabbits From MERS-CoV Infection
- (2016) Katherine V. Houser et al. JOURNAL OF INFECTIOUS DISEASES
- MERS-CoV outbreak following a single patient exposure in an emergency room in South Korea: an epidemiological outbreak study
- (2016) Sun Young Cho et al. LANCET
- 3B11-N, a monoclonal antibody against MERS-CoV, reduces lung pathology in rhesus monkeys following intratracheal inoculation of MERS-CoV Jordan-n3/2012
- (2016) Reed F. Johnson et al. VIROLOGY
- Middle East Respiratory Syndrome Coronavirus (MERS-CoV) origin and animal reservoir
- (2016) Hamzah A. Mohd et al. Virology Journal
- Passive Transfer of A Germline-like Neutralizing Human Monoclonal Antibody Protects Transgenic Mice Against Lethal Middle East Respiratory Syndrome Coronavirus Infection
- (2016) Anurodh Shankar Agrawal et al. Scientific Reports
- Replication and shedding of MERS-CoV in Jamaican fruit bats (Artibeus jamaicensis)
- (2016) Vincent J. Munster et al. Scientific Reports
- A humanized neutralizing antibody against MERS-CoV targeting the receptor-binding domain of the spike protein
- (2015) Yan Li et al. CELL RESEARCH
- Estimating the risk of Middle East respiratory syndrome (MERS) death during the course of the outbreak in the Republic of Korea, 2015
- (2015) Kenji Mizumoto et al. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
- Probable transmission chains of Middle East respiratory syndrome coronavirus and the multiple generations of secondary infection in South Korea
- (2015) Shui Shan Lee et al. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
- Protective Effect of Intranasal Regimens Containing Peptidic Middle East Respiratory Syndrome Coronavirus Fusion Inhibitor Against MERS-CoV Infection
- (2015) Rudragouda Channappanavar et al. JOURNAL OF INFECTIOUS DISEASES
- Two Mutations Were Critical for Bat-to-Human Transmission of Middle East Respiratory Syndrome Coronavirus
- (2015) Yang Yang et al. JOURNAL OF VIROLOGY
- Characterization and Demonstration of the Value of a Lethal Mouse Model of Middle East Respiratory Syndrome Coronavirus Infection and Disease
- (2015) Xinrong Tao et al. JOURNAL OF VIROLOGY
- Intranasally administered peptidic viral fusion inhibitor protected hDPP4 transgenic mice from MERS-CoV infection
- (2015) Shibo Jiang et al. LANCET
- Middle East respiratory syndrome
- (2015) Alimuddin Zumla et al. LANCET
- MERS – A cautionary tale
- (2015) Sophia Häfner et al. MICROBES AND INFECTION
- Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus
- (2015) Davide Corti et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pre- and postexposure efficacy of fully human antibodies against Spike protein in a novel humanized mouse model of MERS-CoV infection
- (2015) Kristen E. Pascal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dromedary Camels and the Transmission of Middle East Respiratory Syndrome Coronavirus (MERS-CoV)
- (2015) M. G. Hemida et al. Transboundary and Emerging Diseases
- Bat-to-human: spike features determining ‘host jump’ of coronaviruses SARS-CoV, MERS-CoV, and beyond
- (2015) Guangwen Lu et al. TRENDS IN MICROBIOLOGY
- An Outbreak of Middle East Respiratory Syndrome Coronavirus Infection in South Korea, 2015
- (2015) Jun Yong Choi YONSEI MEDICAL JOURNAL
- Origin and Possible Genetic Recombination of the Middle East Respiratory Syndrome Coronavirus from the First Imported Case in China: Phylogenetics and Coalescence Analysis
- (2015) Yanqun Wang et al. mBio
- Junctional and allele-specific residues are critical for MERS-CoV neutralization by an exceptionally potent germline-like antibody
- (2015) Tianlei Ying et al. Nature Communications
- Evaluation of candidate vaccine approaches for MERS-CoV
- (2015) Lingshu Wang et al. Nature Communications
- Lessons to learn from MERS-CoV outbreak in South Korea
- (2015) Adnan Khan et al. Journal of Infection in Developing Countries
- Structural basis for the neutralization of MERS-CoV by a human monoclonal antibody MERS-27
- (2015) Xiaojuan Yu et al. Scientific Reports
- Be vigilant: New MERS-CoV outbreaks can occur in the Kingdom of Saudi Arabia
- (2015) Payman Salamati et al. Travel Medicine and Infectious Disease
- Urgent development of effective therapeutic and prophylactic agents to control the emerging threat of Middle East respiratory syndrome (MERS)
- (2015) Lu Lu et al. Emerging Microbes & Infections
- Bat Origins of MERS-CoV Supported by Bat Coronavirus HKU4 Usage of Human Receptor CD26
- (2014) Qihui Wang et al. Cell Host & Microbe
- An Observational, Laboratory-Based Study of Outbreaks of Middle East Respiratory Syndrome Coronavirus in Jeddah and Riyadh, Kingdom of Saudi Arabia, 2014
- (2014) C. Drosten et al. CLINICAL INFECTIOUS DISEASES
- Current advancements and potential strategies in the development of MERS-CoV vaccines
- (2014) Naru Zhang et al. Expert Review of Vaccines
- Inhibition of Proprotein Convertases Abrogates Processing of the Middle Eastern Respiratory Syndrome Coronavirus Spike Protein in Infected Cells but Does Not Reduce Viral Infectivity
- (2014) S. Gierer et al. JOURNAL OF INFECTIOUS DISEASES
- Host Species Restriction of Middle East Respiratory Syndrome Coronavirus through Its Receptor, Dipeptidyl Peptidase 4
- (2014) N. van Doremalen et al. JOURNAL OF VIROLOGY
- Receptor Variation and Susceptibility to Middle East Respiratory Syndrome Coronavirus Infection
- (2014) A. Barlan et al. JOURNAL OF VIROLOGY
- Receptor Recognition Mechanisms of Coronaviruses: a Decade of Structural Studies
- (2014) Fang Li JOURNAL OF VIROLOGY
- Exceptionally Potent Neutralization of Middle East Respiratory Syndrome Coronavirus by Human Monoclonal Antibodies
- (2014) Tianlei Ying et al. JOURNAL OF VIROLOGY
- A Conformation-Dependent Neutralizing Monoclonal Antibody Specifically Targeting Receptor-Binding Domain in Middle East Respiratory Syndrome Coronavirus Spike Protein
- (2014) L. Du et al. JOURNAL OF VIROLOGY
- Evidence for Camel-to-Human Transmission of MERS Coronavirus
- (2014) Esam I. Azhar et al. NEW ENGLAND JOURNAL OF MEDICINE
- Host cell entry of Middle East respiratory syndrome coronavirus after two-step, furin-mediated activation of the spike protein
- (2014) Jean Kaoru Millet et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of human neutralizing antibodies against MERS-CoV and their role in virus adaptive evolution
- (2014) X.-C. Tang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rapid generation of a mouse model for Middle East respiratory syndrome
- (2014) Jincun Zhao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Receptor usage and cell entry of bat coronavirus HKU4 provide insight into bat-to-human transmission of MERS coronavirus
- (2014) Y. Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Soaring MERS Cases in Saudi Arabia Raise Alarms
- (2014) K. Kupferschmidt SCIENCE
- Potent Neutralization of MERS-CoV by Human Neutralizing Monoclonal Antibodies to the Viral Spike Glycoprotein
- (2014) L. Jiang et al. Science Translational Medicine
- Middle East respiratory syndrome coronavirus (MERS-CoV) entry inhibitors targeting spike protein
- (2014) Shuai Xia et al. VIRUS RESEARCH
- IFITM Proteins Inhibit Entry Driven by the MERS-Coronavirus Spike Protein: Evidence for Cholesterol-Independent Mechanisms
- (2014) Florian Wrensch et al. Viruses-Basel
- Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor
- (2014) Lu Lu et al. Nature Communications
- Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP4
- (2013) Nianshuang Wang et al. CELL RESEARCH
- Evolution and Emergence of Therapeutic Monoclonal Antibodies
- (2013) Ian N. Foltz et al. CIRCULATION
- Proteolytic processing, deubiquitinase and interferon antagonist activities of Middle East respiratory syndrome coronavirus papain-like protease
- (2013) X. Yang et al. JOURNAL OF GENERAL VIROLOGY
- Adenosine Deaminase Acts as a Natural Antagonist for Dipeptidyl Peptidase 4-Mediated Entry of the Middle East Respiratory Syndrome Coronavirus
- (2013) V. S. Raj et al. JOURNAL OF VIROLOGY
- Middle East Respiratory Syndrome Coronavirus Infection Mediated by the Transmembrane Serine Protease TMPRSS2
- (2013) Kazuya Shirato et al. JOURNAL OF VIROLOGY
- Inhibition of Middle East Respiratory Syndrome Coronavirus Infection by Anti-CD26 Monoclonal Antibody
- (2013) K. Ohnuma et al. JOURNAL OF VIROLOGY
- Structure of the Fusion Core and Inhibition of Fusion by a Heptad Repeat Peptide Derived from the S Protein of Middle East Respiratory Syndrome Coronavirus
- (2013) J. Gao et al. JOURNAL OF VIROLOGY
- Identification of a Receptor-Binding Domain in the S Protein of the Novel Human Coronavirus Middle East Respiratory Syndrome Coronavirus as an Essential Target for Vaccine Development
- (2013) L. Du et al. JOURNAL OF VIROLOGY
- Crystal Structure of the Receptor-Binding Domain from Newly Emerged Middle East Respiratory Syndrome Coronavirus
- (2013) Y. Chen et al. JOURNAL OF VIROLOGY
- The Spike Protein of the Emerging Betacoronavirus EMC Uses a Novel Coronavirus Receptor for Entry, Can Be Activated by TMPRSS2, and Is Targeted by Neutralizing Antibodies
- (2013) S. Gierer et al. JOURNAL OF VIROLOGY
- Clinical features and viral diagnosis of two cases of infection with Middle East Respiratory Syndrome coronavirus: a report of nosocomial transmission
- (2013) Benoit Guery et al. LANCET
- Middle East respiratory syndrome coronavirus in dromedary camels: an outbreak investigation
- (2013) Bart L Haagmans et al. LANCET INFECTIOUS DISEASES
- Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26
- (2013) Guangwen Lu et al. NATURE
- Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC
- (2013) V. Stalin Raj et al. NATURE
- Role of the Spike Glycoprotein of Human Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in Virus Entry and Syncytia Formation
- (2013) Zhaohui Qian et al. PLoS One
- Reverse genetics with a full-length infectious cDNA of the Middle East respiratory syndrome coronavirus
- (2013) T. Scobey et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Engineering a Replication-Competent, Propagation-Defective Middle East Respiratory Syndrome Coronavirus as a Vaccine Candidate
- (2013) F. Almazan et al. mBio
- Is the discovery of the novel human betacoronavirus 2c EMC/2012 (HCoV-EMC) the beginning of another SARS-like pandemic?
- (2012) Jasper F.W. Chan et al. JOURNAL OF INFECTION
- Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia
- (2012) Ali M. Zaki et al. NEW ENGLAND JOURNAL OF MEDICINE
- Genetic relatedness of the novel human group C betacoronavirus to Tylonycteris bat coronavirus HKU4 and Pipistrellus bat coronavirus HKU5
- (2012) Patrick CY Woo et al. Emerging Microbes & Infections
- The safety and side effects of monoclonal antibodies
- (2010) Trevor T. Hansel et al. NATURE REVIEWS DRUG DISCOVERY
- Therapeutic antibodies: successes, limitations and hopes for the future
- (2009) Patrick Chames et al. BRITISH JOURNAL OF PHARMACOLOGY
- The spike protein of SARS-CoV — a target for vaccine and therapeutic development
- (2009) Lanying Du et al. NATURE REVIEWS MICROBIOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now