Hyperglycemia Induces Trained Immunity in Macrophages and Their Precursors and Promotes Atherosclerosis

Dietary sucrose induces metabolic inflammation and atherosclerotic cardiovascular diseases more than dietary fat in LDLr ApoB100/100 mice

(2020) Laís R. Perazza et al.   ATHEROSCLEROSIS

Transient Intermittent Hyperglycemia Accelerates Atherosclerosis by Promoting Myelopoiesis

(2020) Michelle C Flynn et al.   CIRCULATION RESEARCH

Inhibition of the RUNX1-CBFβ transcription factor complex compromises mammary epithelial cell identity: a phenotype potentially stabilized by mitotic gene bookmarking

(2020) Joshua T. Rose et al.   Oncotarget

Intensive Glucose Control in Patients with Type 2 Diabetes — 15-Year Follow-up

(2019) Peter D. Reaven et al.   NEW ENGLAND JOURNAL OF MEDICINE

Metabolic regulation of gene expression by histone lactylation

(2019) Di Zhang et al.   NATURE

Dysregulation of macrophage development and phenotype in diabetic human macrophages can be rescued by Hoxa3 protein transduction

(2019) Salma Alrdahe et al.   PLoS One

Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming

(2018) Anette Christ et al.   CELL

Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity

(2018) Ioannis Mitroulis et al.   CELL

Metabolic Induction of Trained Immunity through the Mevalonate Pathway

(2018) Siroon Bekkering et al.   CELL

The Changing Landscape of Diabetes Therapy for Cardiovascular Risk Reduction

(2018) Jonathan D. Newman et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The role of the interleukin-1 family in trained immunity

(2017) Simone J.C.F.M. Moorlag et al.   IMMUNOLOGICAL REVIEWS

Metabolic Hallmarks of Tumor and Immune Cells in the Tumor Microenvironment

(2017) Kathrin Renner et al.   Frontiers in Immunology

Monocyte Adhesion and Plaque Recruitment During Atherosclerosis Development Is Regulated by the Adapter Protein Chat-H/SHEP1Highlights

(2016) Olivier Herbin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Inducible chromatin priming is associated with the establishment of immunological memory in T cells

(2016) S. L. Bevington et al.   EMBO JOURNAL

Molecular control of activation and priming in macrophages

(2016) Christopher K Glass et al.   NATURE IMMUNOLOGY

Immunometabolic circuits in trained immunity

(2016) Rob J.W. Arts et al.   SEMINARS IN IMMUNOLOGY

Immunometabolic Pathways in BCG-Induced Trained Immunity

(2016) Rob J.W. Arts et al.   Cell Reports

The RUNX complex: reaching beyond haematopoiesis into immunity

(2015) Dominic Chih-Cheng Voon et al.   IMMUNOLOGY

Immunometabolism governs dendritic cell and macrophage function

(2015) Luke A.J. O’Neill et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Orchestrating high-throughput genomic analysis with Bioconductor

(2015) Wolfgang Huber et al.   NATURE METHODS

Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes

(2015) Bernard Zinman et al.   NEW ENGLAND JOURNAL OF MEDICINE

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

The IL-1 Pathway in Type 2 Diabetes and Cardiovascular Complications

(2015) Christian Herder et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Annexin A2 binds to endosomes and negatively regulates TLR4-triggered inflammatory responses via the TRAM-TRIF pathway

(2015) Shuang Zhang et al.   Scientific Reports

Human CD68 promoter GFP transgenic mice allow analysis of monocyte to macrophage differentiation in vivo

(2014) A. J. Iqbal et al.   BLOOD

Adipose Tissue Macrophages Promote Myelopoiesis and Monocytosis in Obesity

(2014) Prabhakara R. Nagareddy et al.   Cell Metabolism

8. Cardiovascular Disease and Risk Management

(2014)   DIABETES CARE

Metabolic Reprogramming of Macrophages

(2014) Alex J. Freemerman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LC–MS Metabolomics of Psoriasis Patients Reveals Disease Severity-Dependent Increases in Circulating Amino Acids That Are Ameliorated by Anti-TNFα Treatment

(2014) Muhammad Anas Kamleh et al.   JOURNAL OF PROTEOME RESEARCH

mTOR- and HIF-1 -mediated aerobic glycolysis as metabolic basis for trained immunity

(2014) S.-C. Cheng et al.   SCIENCE

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

(2013) G. M. Tannahill et al.   NATURE

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Candida albicans Infection Affords Protection against Reinfection via Functional Reprogramming of Monocytes

(2012) Jessica Quintin et al.   Cell Host & Microbe

Metaboloepigenetics: Interrelationships between energy metabolism and epigenetic control of gene expression

(2012) Dallas R. Donohoe et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Differential oestrogen receptor binding is associated with clinical outcome in breast cancer

(2012) Caryn S. Ross-Innes et al.   NATURE

Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation

(2012) Davis J. McCarthy et al.   NUCLEIC ACIDS RESEARCH

Regression of Atherosclerosis Is Characterized by Broad Changes in the Plaque Macrophage Transcriptome

(2012) Jonathan E. Feig et al.   PLoS One

Identification of benzodiazepine Ro5-3335 as an inhibitor of CBF leukemia through quantitative high throughput screen against RUNX1-CBF  interaction

(2012) L. Cunningham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MEME-ChIP: motif analysis of large DNA datasets

(2011) Philip Machanick et al.   BIOINFORMATICS

A Gene Expression Signature That Classifies Human Atherosclerotic Plaque by Relative Inflammation Status

(2011) Oscar Puig et al.   Circulation-Cardiovascular Genetics

Diabetes Adversely Affects Macrophages During Atherosclerotic Plaque Regression in Mice

(2011) S. Parathath et al.   DIABETES

Long-Term Effects of Intensive Glucose Lowering on Cardiovascular Outcomes

(2011)   NEW ENGLAND JOURNAL OF MEDICINE

Gender-Dependent Correlations of Carotid Intima–Media Thickness with Gene Expression in Blood

(2011) Renée J. Turner et al.   Translational Stroke Research

Assigning roles to DNA regulatory motifs using comparative genomics

(2010) Fabian A. Buske et al.   BIOINFORMATICS

GREAT improves functional interpretation of cis-regulatory regions

(2010) Cory Y McLean et al.   NATURE BIOTECHNOLOGY

UKPDS and the Legacy Effect

(2008) John Chalmers et al.   NEW ENGLAND JOURNAL OF MEDICINE

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY